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    Slc35a1 solute carrier family 35 member A1 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 313139, updated on 9-Dec-2024

    Summary

    Official Symbol
    Slc35a1provided by RGD
    Official Full Name
    solute carrier family 35 member A1provided by RGD
    Primary source
    RGD:1311359
    See related
    EnsemblRapid:ENSRNOG00000008908 AllianceGenome:RGD:1311359
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable CMP-N-acetylneuraminate transmembrane transporter activity and antiporter activity. Predicted to be involved in CMP-N-acetylneuraminate transmembrane transport. Predicted to be located in membrane. Predicted to be active in Golgi membrane. Human ortholog(s) of this gene implicated in congenital disorder of glycosylation type IIf. Orthologous to human SLC35A1 (solute carrier family 35 member A1). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Kidney (RPKM 153.0), Adrenal (RPKM 88.4) and 9 other tissues See more
    Orthologs
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    Genomic context

    See Slc35a1 in Genome Data Viewer
    Location:
    5q21
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 5 NC_086023.1 (54021896..54044677, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 5 NC_051340.1 (49225599..49248382, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 5 NC_005104.4 (50119880..50142689, complement)

    Chromosome 5 - NC_086023.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC134478957 Neighboring gene akirin 2 Neighboring gene origin recognition complex, subunit 3 Neighboring gene arginyl-tRNA synthetase 2, mitochondrial Neighboring gene cilia and flagella associated protein 206 Neighboring gene similar to human chromosome 6 open reading frame 163

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Gene Ontology Provided by RGD

    Component Evidence Code Pubs
    is_active_in Golgi membrane  
    located_in Golgi membrane  
    located_in membrane  

    General protein information

    Preferred Names
    CMP-sialic acid transporter
    Names
    solute carrier family 35 (CMP-sialic acid transporter), member 1
    solute carrier family 35 (CMP-sialic acid transporter), member A1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001107924.2NP_001101394.2  CMP-sialic acid transporter

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000005
      UniProtKB/TrEMBL
      A0A0G2JZH4, D3ZZ48
      Related
      ENSRNOP00000071048.1, ENSRNOT00000081150.3
      Conserved Domains (1) summary
      pfam04142
      Location:8314
      Nuc_sug_transp; Nucleotide-sugar transporter

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086023.1 Reference GRCr8

      Range
      54021896..54044677 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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