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    Zfp652 zinc finger protein 652 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 497984, updated on 27-Nov-2024

    Summary

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    Official Symbol
    Zfp652provided by RGD
    Official Full Name
    zinc finger protein 652provided by RGD
    Primary source
    RGD:1566329
    See related
    EnsemblRapid:ENSRNOG00000017001 AllianceGenome:RGD:1566329
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Znf652; RGD1566329
    Summary
    Predicted to enable DNA-binding transcription factor activity and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Orthologous to human ZNF652 (zinc finger protein 652). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in Lung (RPKM 120.4), Spleen (RPKM 98.8) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Zfp652 in Genome Data Viewer
    Location:
    10q26
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 10 NC_086028.1 (81123326..81203153)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 10 NC_051345.1 (80626555..80706397)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 10 NC_005109.4 (83556809..83572014)

    Chromosome 10 - NC_086028.1Genomic Context describing neighboring genes Neighboring gene nerve growth factor receptor Neighboring gene prohibitin 1 Neighboring gene uncharacterized LOC120095179 Neighboring gene uncharacterized LOC102547047 Neighboring gene phosphoethanolamine/phosphocholine phosphatase 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334, Free PMC Article
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Clone Names

    • MGC156681

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    zinc finger protein 652

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001080207.1 → NP_001073676.1  zinc finger protein 652

      See identical proteins and their annotated locations for NP_001073676.1

      Status: PROVISIONAL

      Source sequence(s)
      BC129097
      UniProtKB/Swiss-Prot
      A1L1J6
      UniProtKB/TrEMBL
      A6HIA9
      Conserved Domains (3) summary
      COG5048
      Location:438 → 487
      COG5048; FOG: Zn-finger [General function prediction only]
      COG5189
      Location:380 → 463
      SFP1; Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning]
      sd00017
      Location:386 → 406
      ZF_C2H2; C2H2 Zn finger [structural motif]

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086028.1 Reference GRCr8

      Range
      81123326..81203153
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039086629.2 → XP_038942557.1  zinc finger protein 652 isoform X1

      UniProtKB/Swiss-Prot
      A1L1J6
      UniProtKB/TrEMBL
      A6HIA9
      Conserved Domains (3) summary
      COG5048
      Location:438 → 487
      COG5048; FOG: Zn-finger [General function prediction only]
      COG5189
      Location:380 → 463
      SFP1; Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning]
      sd00017
      Location:386 → 406
      ZF_C2H2; C2H2 Zn finger [structural motif]

    2. XM_039086628.2 → XP_038942556.1  zinc finger protein 652 isoform X1

      UniProtKB/Swiss-Prot
      A1L1J6
      UniProtKB/TrEMBL
      A6HIA9
      Related
      ENSRNOP00000111957.1, ENSRNOT00000137800.1
      Conserved Domains (3) summary
      COG5048
      Location:438 → 487
      COG5048; FOG: Zn-finger [General function prediction only]
      COG5189
      Location:380 → 463
      SFP1; Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning]
      sd00017
      Location:386 → 406
      ZF_C2H2; C2H2 Zn finger [structural motif]

    3. XM_039086627.2 → XP_038942555.1  zinc finger protein 652 isoform X1

      UniProtKB/Swiss-Prot
      A1L1J6
      UniProtKB/TrEMBL
      A6HIA9
      Related
      ENSRNOP00000052376.2, ENSRNOT00000022811.8
      Conserved Domains (3) summary
      COG5048
      Location:438 → 487
      COG5048; FOG: Zn-finger [General function prediction only]
      COG5189
      Location:380 → 463
      SFP1; Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning]
      sd00017
      Location:386 → 406
      ZF_C2H2; C2H2 Zn finger [structural motif]

    4. XM_039086630.2 → XP_038942558.1  zinc finger protein 652 isoform X2

      UniProtKB/TrEMBL
      A0A8I6G674
      Conserved Domains (3) summary
      COG5048
      Location:258 → 307
      COG5048; FOG: Zn-finger [General function prediction only]
      COG5189
      Location:200 → 283
      SFP1; Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning]
      sd00017
      Location:206 → 226
      ZF_C2H2; C2H2 Zn finger [structural motif]
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A1L1J6.1 GenPept UniProtKB/Swiss-Prot:A1L1J6

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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