Phyhip phytanoyl-CoA 2-hydroxylase interacting protein [Rattus norvegicus (Norway rat)] - Gene

Summary

Symbol: Phyhipprovided by RGD
Full Name: phytanoyl-CoA 2-hydroxylase interacting proteinprovided by RGD
Primary source: RGD:1305790
See related: EnsemblRapid:ENSRNOG00000010555 AllianceGenome:RGD:1305790
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary: Predicted to enable protein tyrosine kinase binding activity. Predicted to be involved in protein localization. Predicted to be active in cytoplasm. Orthologous to human PHYHIP (phytanoyl-CoA 2-hydroxylase interacting protein). [provided by Alliance of Genome Resources, Nov 2024]
Expression: Biased expression in Brain (RPKM 317.4) and Heart (RPKM 40.9) See more
Orthologs: human mouse all
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Genomic context

Location:: 15p11

Exon count:: 6

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	15	NC_086033.1 (51943670..51954921)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	15	NC_051350.1 (45533974..45545223)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	15	NC_005114.4 (52148737..52160283)

Chromosome 15 - NC_086033.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

AW049870 (e-PCR)
- UniSTS:180693

RH129401 (e-PCR)
- UniSTS:212708

Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables protein tyrosine kinase binding	ISO Inferred from Sequence Orthology more info

Process	Evidence Code	Pubs
involved_in protein localization	ISO Inferred from Sequence Orthology more info
involved_in protein localization	ISS Inferred from Sequence or Structural Similarity more info

Component	Evidence Code	Pubs
is_active_in cytoplasm	IBA Inferred from Biological aspect of Ancestor more info
located_in cytoplasm	ISO Inferred from Sequence Orthology more info
located_in cytoplasm	ISS Inferred from Sequence or Structural Similarity more info

General protein information

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Preferred Names: phytanoyl-CoA hydroxylase-interacting protein

Names: PAHX-AP1; PAHXAP1; phytanoyl-CoA hydroxylase-associated protein 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001017376.1 → NP_001017376.1 phytanoyl-CoA hydroxylase-interacting protein

Status: PROVISIONAL

Source sequence(s)

BC092627

UniProtKB/Swiss-Prot

Q568Z9

UniProtKB/TrEMBL

A6HTK5

Related

ENSRNOP00000014441.2, ENSRNOT00000014441.6

Conserved Domains (1) summary

cd00063
Location:5 → 112

FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

NC_086033.1 Reference GRCr8

Range

51943670..51954921

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_039093159.2 → XP_038949087.1 phytanoyl-CoA hydroxylase-interacting protein isoform X1

UniProtKB/Swiss-Prot

Q568Z9

UniProtKB/TrEMBL

A6HTK5

Related

ENSRNOP00000107566.1, ENSRNOT00000147354.1

Conserved Domains (1) summary

cd00063
Location:5 → 112

FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...