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    Rps23 ribosomal protein S23 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 124323, updated on 27-Nov-2024

    Summary

    Official Symbol
    Rps23provided by RGD
    Official Full Name
    ribosomal protein S23provided by RGD
    Primary source
    RGD:621039
    See related
    EnsemblRapid:ENSRNOG00000016580 AllianceGenome:RGD:621039
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to be a structural constituent of ribosome. Predicted to be involved in ribosomal small subunit biogenesis; stress granule assembly; and translation. Part of cytosolic small ribosomal subunit. Human ortholog(s) of this gene implicated in brachycephaly, trichomegaly, and developmental delay. Orthologous to human RPS23 (ribosomal protein S23). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in Spleen (RPKM 7904.4), Thymus (RPKM 5956.5) and 9 other tissues See more
    Orthologs
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    Genomic context

    See Rps23 in Genome Data Viewer
    Location:
    2q12
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 2 NC_086020.1 (23814517..23816087)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 2 NC_051337.1 (22079339..22080909)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 2 NC_005101.4 (19823234..19824804)

    Chromosome 2 - NC_086020.1Genomic Context describing neighboring genes Neighboring gene small nucleolar RNA U109 Neighboring gene transmembrane protein 167A Neighboring gene uncharacterized LOC134485712 Neighboring gene ATPase H+ transporting accessory protein 1 like Neighboring gene autophagy related 10 Neighboring gene uncharacterized LOC120100664 Neighboring gene uncharacterized LOC134485814

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables structural constituent of ribosome IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables structural constituent of ribosome IEA
    Inferred from Electronic Annotation
    more info
     
    enables structural constituent of ribosome ISO
    Inferred from Sequence Orthology
    more info
     
    enables structural constituent of ribosome ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    enables translation regulator activity NAS
    Non-traceable Author Statement
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
     
    involved_in cytoplasmic translation ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in cytoplasmic translation ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in maintenance of translational fidelity ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in maintenance of translational fidelity ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in regulation of translation IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in ribosomal small subunit biogenesis ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in ribosomal small subunit biogenesis ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in stress granule assembly ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in translation IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in translation IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in translation ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in translation ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    Component Evidence Code Pubs
    located_in cytoplasmic side of rough endoplasmic reticulum membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cytosolic ribosome ISO
    Inferred from Sequence Orthology
    more info
     
    part_of cytosolic small ribosomal subunit IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of cytosolic small ribosomal subunit IDA
    Inferred from Direct Assay
    more info
    PubMed 
    part_of cytosolic small ribosomal subunit ISO
    Inferred from Sequence Orthology
    more info
     
    located_in endoplasmic reticulum ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleolus IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in ribosome IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in ribosome NAS
    Non-traceable Author Statement
    more info
    PubMed 
    located_in rough endoplasmic reticulum IEA
    Inferred from Electronic Annotation
    more info
     
    part_of small ribosomal subunit IDA
    Inferred from Direct Assay
    more info
    PubMed 
    part_of small ribosomal subunit IEA
    Inferred from Electronic Annotation
    more info
     
    part_of small-subunit processome ISO
    Inferred from Sequence Orthology
    more info
     
    part_of small-subunit processome ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    is_active_in synapse ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    small ribosomal subunit protein uS12
    Names
    40S ribosomal protein S23

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_078617.3NP_511172.1  small ribosomal subunit protein uS12

      See identical proteins and their annotated locations for NP_511172.1

      Status: PROVISIONAL

      Source sequence(s)
      BC058134
      UniProtKB/Swiss-Prot
      P62268
      UniProtKB/TrEMBL
      A6I4N9
      Related
      ENSRNOP00000022348.6, ENSRNOT00000022348.8
      Conserved Domains (1) summary
      PTZ00067
      Location:1143
      PTZ00067; 40S ribosomal S23; Provisional

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086020.1 Reference GRCr8

      Range
      23814517..23816087
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)