Putative AT-hook DNA-binding family protein [Arabidopsis thaliana (thale cress)] - Gene

Summary

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Official Full Name: Putative AT-hook DNA-binding family protein
Primary source: TAIR:AT2G42940
Locus tag: AT2G42940
See related: Araport:AT2G42940
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Arabidopsis thaliana (ecotype: Columbia)
Lineage: Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as: AHL16; AT-hook motif nuclear-localized protein 16; F23E6.8; F23E6_8; TEK; TRANSPOSABLE ELEMENT SILENCING VIA AT-HOOK
Summary: Encodes a nuclear matrix protein with AT-hook DNA binding motifs that acts in the maintenance of genomic integrity by silencing TEs and repeat-containing genes through epigenetic machinery. It interacts with FVE and MSI5 which are components of HDAC corepressor complexes. It is expressed in tapetum during the tetrad stage.
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Genomic context

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See in Genome Data Viewer

Location:: chromosome: 2

Exon count:: 1

Sequence:: Chromosome: 2; NC_003071.7 (17862254..17863456, complement)

Chromosome 2 - NC_003071.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003071.7

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Results showed that the correct regulation of timing of TEK expression is required for pollen wall exine patterning and is coordinated with other pollen developmental events for the processes of pollen wall formation and pollen grain maturation.
Title: The temporal regulation of TEK contributes to pollen wall exine patterning.
MADS AFFECTING FLOWERING 4 (MAF4) and MAF5 are upregulated in TEK knockdown plants. TEK negatively regulates floral repressors including MAF4 and MAF5. [TEK]
Title: The AT-hook/PPC domain protein TEK negatively regulates floral repressors including MAF4 and MAF5.

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Homology

Orthologs from OrthoDB

NM_129855.3

Supported by ESTs:

Gene Ontology Provided by TAIR

Function	Evidence Code	Pubs
enables chromatin DNA binding	IDA Inferred from Direct Assay more info	PubMed
enables minor groove of adenine-thymine-rich DNA binding	IEA Inferred from Electronic Annotation more info
enables protein binding	IPI Inferred from Physical Interaction more info	PubMed

Process	Evidence Code	Pubs
acts_upstream_of_or_within epigenetic regulation of gene expression	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within pollen wall assembly	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in pollen wall assembly	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within transposable element silencing by heterochromatin formation	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within vegetative to reproductive phase transition of meristem	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in vegetative to reproductive phase transition of meristem	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
located_in nucleus	IDA Inferred from Direct Assay more info	PubMed
located_in nucleus	ISM Inferred from Sequence Model more info

General protein information

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Preferred Names: Putative AT-hook DNA-binding family protein

NP_181822.1

Predicted AT-hook DNA-binding family protein; FUNCTIONS IN: DNA binding; INVOLVED IN: biological_process unknown; LOCATED IN: chloroplast; EXPRESSED IN: leaf whorl, sepal, flower; EXPRESSED DURING: petal differentiation and expansion stage; CONTAINS InterPro DOMAIN/s: Protein of unknown function DUF296 (InterPro:IPR005175), AT hook, DNA-binding motif (InterPro:IPR017956), Predicted AT-hook DNA-binding (InterPro:IPR014476); BEST Arabidopsis thaliana protein match is: Predicted AT-hook DNA-binding family protein (TAIR:AT2G35270.1); Has 767 Blast hits to 762 proteins in 28 species: Archae - 0; Bacteria - 10; Metazoa - 0; Fungi - 0; Plants - 756; Viruses - 0; Other Eukaryotes - 1 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003071.7 Reference assembly

Range

17862254..17863456 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_129855.3 → NP_181822.1 Putative AT-hook DNA-binding family protein [Arabidopsis thaliana]

See identical proteins and their annotated locations for NP_181822.1

Status: REVIEWED

UniProtKB/Swiss-Prot

Q9SJG4

UniProtKB/TrEMBL

A0A178VQG3, A0A5S9X6J0

Conserved Domains (1) summary

pfam03479
Location:84 → 194

DUF296; Domain of unknown function (DUF296)