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    transcription regulator [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 839244, updated on 18-Sep-2024

    Summary

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    Official Full Name
    transcription regulator
    Primary source
    TAIR:AT1G02080
    Locus tag
    AT1G02080
    See related
    Araport:AT1G02080
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    T7I23.15; T7I23_15
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    Genomic context

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    Location:
    chromosome: 1
    Exon count:
    50
    Sequence:
    Chromosome: 1; NC_003070.9 (373335..386913)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene squamosa promoter binding protein-like 8 Neighboring gene zinc ion-binding protein Neighboring gene Proteasome component (PCI) domain protein Neighboring gene Leucine carboxyl methyltransferase

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The CCR4-NOT complex component NOT1 regulates RNA-directed DNA methylation and transcriptional silencing by facilitating Pol IV-dependent siRNA production. Zhou HR, et al. Plant J, 2020 Aug. PMID 32412137
    2. AtNOT1 is required for gametophyte development in Arabidopsis. Pereira PA, et al. Plant J, 2020 Aug. PMID 32369648
    3. AtNOT1 Is a Novel Regulator of Gene Expression during Pollen Development. Motomura K, et al. Plant Cell Physiol, 2020 Apr 1. PMID 31879778
    4. Identification of Arabidopsis CCR4-NOT Complexes with Pumilio RNA-Binding Proteins, APUM5 and APUM2. Arae T, et al. Plant Cell Physiol, 2019 Sep 1. PMID 31093672
    5. Protein and metabolite composition of Arabidopsis stress granules. Kosmacz M, et al. New Phytol, 2019 May. PMID 30664249

    See all (9) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. The CCR4-NOT complex component NOT1 regulates RNA-directed DNA methylation and transcriptional silencing by facilitating Pol IV-dependent siRNA production.
      Title: The CCR4-NOT complex component NOT1 regulates RNA-directed DNA methylation and transcriptional silencing by facilitating Pol IV-dependent siRNA production.
    2. AtNOT1 is required for gametophyte development in Arabidopsis.
      Title: AtNOT1 is required for gametophyte development in Arabidopsis.
    3. AtNOT1 Is a Novel Regulator of Gene Expression during Pollen Development.
      Title: AtNOT1 Is a Novel Regulator of Gene Expression during Pollen Development.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_001197960.2
    NM_001331324.1
    NM_100088.5

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in negative regulation of translation IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    part_of CCR4-NOT core complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in cytoplasmic stress granule IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in extracellular region HDA PubMed 

    General protein information

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    Preferred Names
    transcription regulator
    NP_001184889.1
    • transcription regulators; FUNCTIONS IN: transcription regulator activity; EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: CCR4-Not complex component, Not1 (InterPro:IPR007196).
    NP_171710.4
    • transcription regulators; FUNCTIONS IN: transcription regulator activity; LOCATED IN: membrane; EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: CCR4-Not complex component, Not1 (InterPro:IPR007196); Has 1434 Blast hits to 680 proteins in 246 species: Archae - 0; Bacteria - 196; Metazoa - 419; Fungi - 362; Plants - 144; Viruses - 0; Other Eukaryotes - 313 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      373335..386913
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_100088.5 → NP_171710.4  transcription regulator [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_171710.4

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178WMT9, F4HVV6
      Conserved Domains (5) summary
      pfam04054
      Location:2048 → 2403
      Not1; CCR4-Not complex component, Not1
      pfam12842
      Location:1343 → 1483
      DUF3819; Domain of unknown function (DUF3819)
      pfam16415
      Location:995 → 1218
      CNOT1_CAF1_bind; CCR4-NOT transcription complex subunit 1 CAF1-binding domain
      pfam16417
      Location:700 → 877
      CNOT1_TTP_bind; CCR4-NOT transcription complex subunit 1 TTP binding domain
      pfam16418
      Location:527 → 674
      CNOT1_HEAT; CCR4-NOT transcription complex subunit 1 HEAT repeat

    2. NM_001197960.2 → NP_001184889.1  transcription regulator [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001184889.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178WMT9, F4HVV7
      Conserved Domains (5) summary
      pfam04054
      Location:1994 → 2349
      Not1; CCR4-Not complex component, Not1
      pfam12842
      Location:1289 → 1429
      DUF3819; Domain of unknown function (DUF3819)
      pfam16415
      Location:941 → 1164
      CNOT1_CAF1_bind; CCR4-NOT transcription complex subunit 1 CAF1-binding domain
      pfam16417
      Location:646 → 823
      CNOT1_TTP_bind; CCR4-NOT transcription complex subunit 1 TTP binding domain
      pfam16418
      Location:473 → 620
      CNOT1_HEAT; CCR4-NOT transcription complex subunit 1 HEAT repeat

    3. NM_001331324.1 → NP_001321578.1  transcription regulator [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178WMX0, A0A1P8ARB7
    Nucleotide Protein
    Heading Accession and Version

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