U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    UPB1 transcription factor UPBEAT protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 819340, updated on 18-Sep-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    UPB1
    Official Full Name
    transcription factor UPBEAT protein
    Primary source
    TAIR:AT2G47270
    Locus tag
    AT2G47270
    See related
    Araport:AT2G47270
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    T8I13.11; UPBEAT1
    Summary
    Encodes UPBEAT1 (UPB1), a transcription factor with a bHLH domain. Regulates the expression of a set of peroxidases that modulate the balance of reactive oxygen species (ROS) between the zones of cell proliferation and the zone of cell elongation where differentiation begins. Disruption of UPB1 activity alters this ROS balance, leading to a delay in the onset of differentiation.
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See UPB1 in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    1
    Sequence:
    Chromosome: 2; NC_003071.7 (19411430..19412328, complement)

    Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene RNA helicase family protein Neighboring gene WRKY DNA-binding protein 23 Neighboring gene ncRNA Neighboring gene ncRNA

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_003071.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Root-specific photoreception directs early root development by HY5-regulated ROS balance. Li J, et al. Proc Natl Acad Sci U S A, 2024 Feb 6. PMID 38300870, Free PMC Article
    2. The bHLH transcription factor gene AtUPB1 regulates growth by mediating cell cycle progression in Arabidopsis. Li T, et al. Biochem Biophys Res Commun, 2019 Oct 20. PMID 31445703
    3. Transcriptional regulation of ROS controls transition from proliferation to differentiation in the root. Tsukagoshi H, et al. Cell, 2010 Nov 12. PMID 21074051
    4. Brassinosteroids regulate root meristem development by mediating BIN2-UPB1 module in Arabidopsis. Li T, et al. PLoS Genet, 2020 Jul. PMID 32609718, Free PMC Article
    5. The Arabidopsis basic/helix-loop-helix transcription factor family. Toledo-Ortiz G, et al. Plant Cell, 2003 Aug. PMID 12897250, Free PMC Article

    See all (10) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Brassinosteroids regulate root meristem development by mediating BIN2-UPB1 module in Arabidopsis.
      Title: Brassinosteroids regulate root meristem development by mediating BIN2-UPB1 module in Arabidopsis.
    2. The transcription factor gene UPB1 is involved in mediating cell cycle progression and root development. UPB1 change the cell cycle progress in G2-M phase to regulate root growth.
      Title: The bHLH transcription factor gene AtUPB1 regulates growth by mediating cell cycle progression in Arabidopsis.
    3. UPB1 provides a direct transcriptional link between ROS distribution and the proliferation status of the cells in the root tip. [UPBEAT1] [UPB1]
      Title: Transcriptional regulation of ROS controls transition from proliferation to differentiation in the root.
    Submit: New GeneRIF Correction

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help
    NM_130295.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables DNA-binding transcription factor activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables protein dimerization activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables transcription cis-regulatory region binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within regulation of DNA-templated transcription TAS
    Traceable Author Statement
    more info
    		 PubMed 
    acts_upstream_of_or_within regulation of root development IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in response to absence of light IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in mitochondrion ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    transcription factor UPBEAT protein
    NP_566098.1
    • sequence-specific DNA binding transcription factors;transcription regulators; Has 43 Blast hits to 43 proteins in 10 species: Archae - 0; Bacteria - 0; Metazoa - 0; Fungi - 0; Plants - 43; Viruses - 0; Other Eukaryotes - 0 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003071.7 Reference assembly

      Range
      19411430..19412328 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_130295.3 → NP_566098.1  transcription factor UPBEAT protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_566098.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      C0SV93, O22901, Q8LDJ3
      UniProtKB/TrEMBL
      A0A178VV95, A0A5S9X7T4
      Conserved Domains (1) summary
      cd11444
      Location:39 → 93
      bHLH_AtIBH1_like; basic helix-loop-helix (bHLH) domain found in Arabidopsis thaliana ILI1-BINDING BHLH 1 (IBH1) and similar proteins
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    O22901.1

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.