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    WAK4 wall associated kinase 4 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 838716, updated on 18-Sep-2024

    Summary

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    Official Symbol
    WAK4
    Official Full Name
    wall associated kinase 4
    Primary source
    TAIR:AT1G21210
    Locus tag
    AT1G21210
    See related
    Araport:AT1G21210
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    F16F4.10; F16F4_10; wall associated kinase 4
    Summary
    cell wall-associated ser/thr kinase involved in cell elongation and lateral root development
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    Genomic context

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    See WAK4 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    4
    Sequence:
    Chromosome: 1; NC_003070.9 (7423704..7427041)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene Small nuclear ribonucleoprotein family protein Neighboring gene sequence-specific DNA binding transcription factor Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene pseudo Neighboring gene wall associated kinase 5

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Antisense expression of a cell wall-associated protein kinase, WAK4, inhibits cell elongation and alters morphology. Lally D, et al. Plant Cell, 2001 Jun. PMID 11402163, Free PMC Article
    2. A cluster of five cell wall-associated receptor kinase genes, Wak1-5, are expressed in specific organs of Arabidopsis. He ZH, et al. Plant Mol Biol, 1999 Apr. PMID 10380805
    3. Border control--a membrane-linked interactome of Arabidopsis. Jones AM, et al. Science, 2014 May 16. PMID 24833385
    4. Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana. Theologis A, et al. Nature, 2000 Dec 14. PMID 11130712

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables calcium ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables polysaccharide binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in cell surface receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within lateral root development IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within unidimensional cell growth IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in extracellular region ISM
    Inferred from Sequence Model
    more info
    		  
    located_in plasma membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    wall associated kinase 4
    NP_173544.1
    • wall associated kinase 4 (WAK4); FUNCTIONS IN: protein serine/threonine kinase activity, protein kinase activity, ATP binding, calcium ion binding; INVOLVED IN: protein amino acid phosphorylation, unidimensional cell growth, lateral root development; LOCATED IN: plasma membrane; EXPRESSED IN: root, trichome; CONTAINS InterPro DOMAIN/s: EGF-like calcium-binding (InterPro:IPR001881), EGF-like, type 3 (InterPro:IPR000742), Serine-threonine/tyrosine-protein kinase (InterPro:IPR001245), Protein kinase-like domain (InterPro:IPR011009), Serine/threonine-protein kinase, active site (InterPro:IPR008271), Protein kinase, catalytic domain (InterPro:IPR000719), EGF-like calcium-binding, conserved site (InterPro:IPR018097), EGF-type aspartate/asparagine hydroxylation site (InterPro:IPR000152), EGF calcium-binding (InterPro:IPR013091), EGF-like (InterPro:IPR006210); BEST Arabidopsis thaliana protein match is: wall-associated kinase 2 (TAIR:AT1G21270.1); Has 129683 Blast hits to 121711 proteins in 4745 species: Archae - 127; Bacteria - 14044; Metazoa - 54379; Fungi - 9626; Plants - 33474; Viruses - 427; Other Eukaryotes - 17606 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      7423704..7427041
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_101974.3 → NP_173544.1  wall associated kinase 4 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_173544.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O81819, Q9LMN6
      UniProtKB/TrEMBL
      A0A178W780
      Conserved Domains (3) summary
      cd14066
      Location:416 → 683
      STKc_IRAK; Catalytic domain of the Serine/Threonine kinases, Interleukin-1 Receptor Associated Kinases and related STKs
      pfam07645
      Location:279 → 324
      EGF_CA; Calcium-binding EGF domain
      pfam13947
      Location:25 → 125
      GUB_WAK_bind; Wall-associated receptor kinase galacturonan-binding
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9LMN6.1

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