PEX19-1 peroxin 19-1 [Arabidopsis thaliana (thale cress)] - Gene

Summary

Official Symbol: PEX19-1
Official Full Name: peroxin 19-1
Primary source: TAIR:AT3G03490
Locus tag: AT3G03490
See related: Araport:AT3G03490
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Arabidopsis thaliana (ecotype: Columbia)
Lineage: Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as: AtPEX19-1; peroxin 19-1; T21P5.9; T21P5_9
Summary: Encodes one of two PEX19 peroxin isoforms. It is predominantly cytosolic and forms dimers.
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Chromosome 3 - NC_003074.8 Genomic Context describing neighboring genes

Go to nucleotide: Graphics FASTA GenBank

PEX19 promotes peroxisome function and is essential for viability in Arabidopsis thaliana.
Title: The Early-Acting Peroxin PEX19 Is Redundantly Encoded, Farnesylated, and Essential for Viability in Arabidopsis thaliana.
Pseudo half-molecules of the ABC transporter, COMATOSE, bind Pex19 and target to peroxisomes independently but are both required for activity
Title: Pseudo half-molecules of the ABC transporter, COMATOSE, bind Pex19 and target to peroxisomes independently but are both required for activity.
AtPEX19-1 was shown to bind to the Arabidopsis peroxisomal membrane protein PEX10. (AtPex19-1)
Title: Arabidopsis PEX19 is a dimeric protein that binds the peroxin PEX10.

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

NM_111220.4

Function	Evidence Code	Pubs
enables identical protein binding	IPI Inferred from Physical Interaction more info	PubMed
enables protein binding	IPI Inferred from Physical Interaction more info	PubMed

Process	Evidence Code	Pubs
acts_upstream_of_or_within peroxisome organization	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
located_in cytosol	IDA Inferred from Direct Assay more info	PubMed
located_in nucleus	ISM Inferred from Sequence Model more info

NP_186999.1

peroxin 19-1 (PEX19-1); CONTAINS InterPro DOMAIN/s: Pex19 protein (InterPro:IPR006708); BEST Arabidopsis thaliana protein match is: peroxin 19-2 (TAIR:AT5G17550.1); Has 637 Blast hits to 625 proteins in 250 species: Archae - 3; Bacteria - 161; Metazoa - 169; Fungi - 149; Plants - 43; Viruses - 0; Other Eukaryotes - 112 (source: NCBI BLink).