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    IGPD imidazoleglycerol-phosphate dehydratase [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 821812, updated on 18-Sep-2024

    Summary

    Official Symbol
    IGPD
    Official Full Name
    imidazoleglycerol-phosphate dehydratase
    Primary source
    TAIR:AT3G22425
    Locus tag
    AT3G22425
    See related
    Araport:AT3G22425
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    HISN5A; imidazoleglycerol-phosphate dehydratase; IMIDAZOLEGLYCEROLPHOSPHATE DEHYDRATASE
    Summary
    Encodes imidazoleglycerolphosphate dehydratase.
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    Genomic context

    See IGPD in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    8
    Sequence:
    Chromosome: 3; NC_003074.8 (7951023..7953223)

    Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene with no lysine (K) kinase 2 Neighboring gene F-box/associated interaction domain protein Neighboring gene RNA recognition motif XS domain protein Neighboring gene uncharacterized protein Neighboring gene miscRNA

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    NM_180293.1
    NM_180294.2

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables imidazoleglycerol-phosphate dehydratase activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in chloroplast ISM
    Inferred from Sequence Model
    more info
     

    General protein information

    Preferred Names
    imidazoleglycerol-phosphate dehydratase
    NP_850624.1
    • imidazoleglycerol-phosphate dehydratase (IGPD); FUNCTIONS IN: imidazoleglycerol-phosphate dehydratase activity; INVOLVED IN: histidine biosynthetic process; LOCATED IN: chloroplast; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Imidazoleglycerol-phosphate dehydratase, conserved site (InterPro:IPR020565), Ribosomal protein S5 domain 2-type fold (InterPro:IPR020568), Imidazoleglycerol-phosphate dehydratase (InterPro:IPR000807); BEST Arabidopsis thaliana protein match is: HISTIDINE BIOSYNTHESIS 5B (TAIR:AT4G14910.1); Has 6614 Blast hits to 6614 proteins in 2210 species: Archae - 198; Bacteria - 4100; Metazoa - 4; Fungi - 195; Plants - 86; Viruses - 0; Other Eukaryotes - 2031 (source: NCBI BLink).
    NP_850625.1
    • imidazoleglycerol-phosphate dehydratase (IGPD); FUNCTIONS IN: imidazoleglycerol-phosphate dehydratase activity; INVOLVED IN: histidine biosynthetic process; LOCATED IN: chloroplast; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Imidazoleglycerol-phosphate dehydratase, conserved site (InterPro:IPR020565), Ribosomal protein S5 domain 2-type fold (InterPro:IPR020568), Imidazoleglycerol-phosphate dehydratase (InterPro:IPR000807); BEST Arabidopsis thaliana protein match is: HISTIDINE BIOSYNTHESIS 5B (TAIR:AT4G14910.1); Has 6872 Blast hits to 6870 proteins in 2212 species: Archae - 198; Bacteria - 4110; Metazoa - 4; Fungi - 197; Plants - 87; Viruses - 0; Other Eukaryotes - 2276 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003074.8 Reference assembly

      Range
      7951023..7953223
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_180294.2NP_850625.1  imidazoleglycerol-phosphate dehydratase [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_850625.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P34047, Q67YN9, Q67YZ9, Q8VYM1
      UniProtKB/TrEMBL
      A0A178VKN0, A0A654FBJ8
      Conserved Domains (1) summary
      PLN02800
      Location:8269
      PLN02800; imidazoleglycerol-phosphate dehydratase
    2. NM_180293.1NP_850624.1  imidazoleglycerol-phosphate dehydratase [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_850624.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P34047
      Conserved Domains (2) summary
      PLN02800
      Location:8264
      PLN02800; imidazoleglycerol-phosphate dehydratase
      PRK00951
      Location:74204
      hisB; imidazoleglycerol-phosphate dehydratase; Validated