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    PUM6 pumilio 6 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 828694, updated on 18-Sep-2024

    Summary

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    Official Symbol
    PUM6
    Official Full Name
    pumilio 6
    Primary source
    TAIR:AT4G25880
    Locus tag
    AT4G25880
    See related
    Araport:AT4G25880
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    APUM6; F14M19.160; F14M19_160; pumilio 6
    Summary
    Encodes a member of the Arabidopsis Pumilio (APUM) proteins containing PUF domain (eight repeats of approximately 36 amino acids each). PUF proteins regulate both mRNA stability and translation through sequence-specific binding to the 3' UTR of target mRNA transcripts.
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    Genomic context

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    See PUM6 in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    10
    Sequence:
    Chromosome: 4; NC_003075.7 (13154708..13159382)

    Chromosome 4 - NC_003075.7Genomic Context describing neighboring genes Neighboring gene miscRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene 60S acidic ribosomal protein family Neighboring gene Galactose mutarotase-like superfamily protein Neighboring gene NFU domain protein 3

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003075.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Plant PUF RNA-binding proteins: A wealth of diversity for post-transcriptional gene regulation. Joshna CR, et al. Plant Sci, 2020 Aug. PMID 32563454
    2. Molecular characterization of Arabidopsis thaliana PUF proteins--binding specificity and target candidates. Francischini CW, et al. FEBS J, 2009 Oct. PMID 19682068
    3. In Planta Determination of the mRNA-Binding Proteome of Arabidopsis Etiolated Seedlings. Reichel M, et al. Plant Cell, 2016 Oct. PMID 27729395, Free PMC Article
    4. Discovering the RNA-Binding Proteome of Plant Leaves with an Improved RNA Interactome Capture Method. Bach-Pages M, et al. Biomolecules, 2020 Apr 24. PMID 32344669, Free PMC Article
    5. Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana. Mayer K, et al. Nature, 1999 Dec 16. PMID 10617198

    GeneRIFs: Gene References Into Functions

    General gene information

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    NM_001036643.2
    NM_001341767.1
    NM_001341768.1
    NM_118721.3
    NM_202889.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables mRNA binding HDA PubMed 
    enables mRNA binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in endoplasmic reticulum IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    pumilio 6
    NP_001031720.1
    • pumilio 6 (PUM6); FUNCTIONS IN: RNA binding, binding; LOCATED IN: chloroplast; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Pumilio RNA-binding repeat (InterPro:IPR001313), Armadillo-like helical (InterPro:IPR011989), Armadillo-type fold (InterPro:IPR016024); BEST Arabidopsis thaliana protein match is: pumilio 5 (TAIR:AT3G20250.1); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).
    NP_567733.1
    • pumilio 6 (PUM6); FUNCTIONS IN: RNA binding, binding; LOCATED IN: chloroplast; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Pumilio RNA-binding repeat (InterPro:IPR001313), Armadillo-like helical (InterPro:IPR011989), Armadillo-type fold (InterPro:IPR016024); BEST Arabidopsis thaliana protein match is: pumilio 5 (TAIR:AT3G20250.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).
    NP_974618.2
    • pumilio 6 (PUM6); FUNCTIONS IN: RNA binding, binding; LOCATED IN: chloroplast; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Pumilio RNA-binding repeat (InterPro:IPR001313), Armadillo-like helical (InterPro:IPR011989), Armadillo-type fold (InterPro:IPR016024); BEST Arabidopsis thaliana protein match is: pumilio 5 (TAIR:AT3G20250.1); Has 3872 Blast hits to 2064 proteins in 251 species: Archae - 0; Bacteria - 18; Metazoa - 936; Fungi - 1249; Plants - 864; Viruses - 0; Other Eukaryotes - 805 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003075.7 Reference assembly

      Range
      13154708..13159382
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_118721.3 → NP_567733.1  pumilio 6 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_567733.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      C0Z2M6, Q2V3E7, Q3E9W4, Q9C5E7, Q9SVZ7
      UniProtKB/TrEMBL
      A0A178V2V1
      Conserved Domains (2) summary
      cd07920
      Location:527 → 848
      Pumilio; Pumilio-family RNA binding domain
      COG5099
      Location:71 → 850
      COG5099; RNA-binding protein of the Puf family, translational repressor [Translation, ribosomal structure and biogenesis]

    2. NM_202889.3 → NP_974618.2  pumilio 6 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_974618.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178V2V1
      Conserved Domains (2) summary
      cd07920
      Location:527 → 842
      Pumilio; Pumilio-family RNA binding domain
      COG5099
      Location:71 → 844
      COG5099; RNA-binding protein of the Puf family, translational repressor [Translation, ribosomal structure and biogenesis]

    3. NM_001036643.2 → NP_001031720.1  pumilio 6 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001031720.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178V537
      Conserved Domains (2) summary
      cd07920
      Location:527 → 842
      Pumilio; Pumilio-family RNA binding domain
      COG5099
      Location:71 → 844
      COG5099; RNA-binding protein of the Puf family, translational repressor [Translation, ribosomal structure and biogenesis]

    4. NM_001341767.1 → NP_001329827.1  pumilio 6 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178V537

    5. NM_001341768.1 → NP_001329828.1  pumilio 6 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      C0Z2M6, Q2V3E7, Q3E9W4, Q9C5E7, Q9SVZ7
      UniProtKB/TrEMBL
      A0A178V2V1
      Conserved Domains (2) summary
      cd07920
      Location:527 → 848
      Pumilio; Pumilio-family RNA binding domain
      COG5099
      Location:71 → 850
      COG5099; RNA-binding protein of the Puf family, translational repressor [Translation, ribosomal structure and biogenesis]
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9C5E7.1

    Gene LinkOut

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