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    TIM8 translocase inner membrane subunit 8 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 835153, updated on 18-Sep-2024

    Summary

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    Official Symbol
    TIM8
    Official Full Name
    translocase inner membrane subunit 8
    Primary source
    TAIR:AT5G50810
    Locus tag
    AT5G50810
    See related
    Araport:AT5G50810
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    K7B16.3; K7B16_3; translocase inner membrane subunit 8
    Summary
    Encodes a small zinc finger-like protein that is a component of the mitochondrial protein import apparatus.
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    Genomic context

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    See TIM8 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    2
    Sequence:
    Chromosome: 5; NC_003076.8 (20675605..20676702, complement)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene Nodulin MtN3 family protein Neighboring gene tRNA-Gln Neighboring gene NAC domain containing protein 97 Neighboring gene nuclear polyadenylated RNA-binding protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A transcriptomic and proteomic characterization of the Arabidopsis mitochondrial protein import apparatus and its response to mitochondrial dysfunction. Lister R, et al. Plant Physiol, 2004 Feb. PMID 14730085, Free PMC Article
    2. Putative glycosyltransferases and other plant Golgi apparatus proteins are revealed by LOPIT proteomics. Nikolovski N, et al. Plant Physiol, 2012 Oct. PMID 22923678, Free PMC Article
    3. A proteomic strategy for global analysis of plant protein complexes. Aryal UK, et al. Plant Cell, 2014 Oct. PMID 25293756, Free PMC Article
    4. A Pan-plant Protein Complex Map Reveals Deep Conservation and Novel Assemblies. McWhite CD, et al. Cell, 2020 Apr 16. PMID 32191846, Free PMC Article
    5. Evidence for network evolution in an Arabidopsis interactome map. Arabidopsis Interactome Mapping Consortium. Science, 2011 Jul 29. PMID 21798944, Free PMC Article

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_124459.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    located_in chloroplast ISM
    Inferred from Sequence Model
    more info
    		  
    located_in cytosol HDA PubMed 
    located_in mitochondrial intermembrane space HDA PubMed 
    located_in mitochondrion HDA PubMed 
    located_in plastid HDA PubMed 

    General protein information

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    Preferred Names
    translocase inner membrane subunit 8
    NP_199894.1
    • translocase inner membrane subunit 8 (TIM8); FUNCTIONS IN: P-P-bond-hydrolysis-driven protein transmembrane transporter activity; INVOLVED IN: protein targeting to mitochondrion, protein import into mitochondrial inner membrane; LOCATED IN: mitochondrion, mitochondrial inner membrane, mitochondrial intermembrane space; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Mitochondrial inner membrane translocase complex, Tim8/9/10/13-zinc finger-like (InterPro:IPR004217); Has 688 Blast hits to 688 proteins in 171 species: Archae - 0; Bacteria - 0; Metazoa - 361; Fungi - 183; Plants - 116; Viruses - 0; Other Eukaryotes - 28 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      20675605..20676702 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_124459.4 → NP_199894.1  translocase inner membrane subunit 8 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_199894.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9XGY4
      UniProtKB/TrEMBL
      A0A5S9YCZ4, A0A654GA21
      Conserved Domains (1) summary
      pfam02953
      Location:13 → 74
      zf-Tim10_DDP; Tim10/DDP family zinc finger
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9XGY4.1

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