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    IMPA-8 importin alpha isoform 8 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 835275, updated on 18-Sep-2024

    Summary

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    Official Symbol
    IMPA-8
    Official Full Name
    importin alpha isoform 8
    Primary source
    TAIR:AT5G52000
    Locus tag
    AT5G52000
    See related
    Araport:AT5G52000
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    importin alpha isoform 8; MSG15.24; MSG15_24
    Summary
    Putative importin alpha isoform. When overexpressed can rescue the impa-4 decreased transformation susceptibility phenotype. Target promoter of the male germline-specific transcription factor DUO1.
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    Genomic context

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    See IMPA-8 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    10
    Sequence:
    Chromosome: 5; NC_003076.8 (21118946..21121119, complement)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene GroES-like zinc-binding alcohol dehydrogenase family protein Neighboring gene Transducin/WD40 repeat-like superfamily protein Neighboring gene C-repeat-binding factor 4 Neighboring gene C2H2-like zinc finger protein Neighboring gene Integrase-type DNA-binding superfamily protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The R2R3 MYB transcription factor DUO1 activates a male germline-specific regulon essential for sperm cell differentiation in Arabidopsis. Borg M, et al. Plant Cell, 2011 Feb. PMID 21285328, Free PMC Article
    2. A Pan-plant Protein Complex Map Reveals Deep Conservation and Novel Assemblies. McWhite CD, et al. Cell, 2020 Apr 16. PMID 32191846, Free PMC Article
    3. Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana. Tabata S, et al. Nature, 2000 Dec 14. PMID 11130714

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables nuclear import signal receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within pollen sperm cell differentiation IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    involved_in protein import into nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in cytoplasm ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    importin alpha isoform 8
    NP_200013.1
    • importin alpha isoform 8 (IMPA-8); FUNCTIONS IN: protein transporter activity, binding; INVOLVED IN: intracellular protein transport; LOCATED IN: cellular_component unknown; EXPRESSED IN: sperm cell, flower; EXPRESSED DURING: petal differentiation and expansion stage; CONTAINS InterPro DOMAIN/s: Armadillo-like helical (InterPro:IPR011989), Armadillo (InterPro:IPR000225), HEAT, type 2 (InterPro:IPR021133), Armadillo-type fold (InterPro:IPR016024); BEST Arabidopsis thaliana protein match is: importin alpha isoform 1 (TAIR:AT3G06720.2); Has 3277 Blast hits to 2522 proteins in 278 species: Archae - 2; Bacteria - 4; Metazoa - 1316; Fungi - 608; Plants - 711; Viruses - 0; Other Eukaryotes - 636 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      21118946..21121119 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_124579.2 → NP_200013.1  importin alpha isoform 8 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_200013.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9FJ92
      UniProtKB/TrEMBL
      A0A5S9YD78
      Conserved Domains (5) summary
      cd00020
      Location:171 → 284
      ARM; Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin, ...
      pfam13646
      Location:51 → 156
      HEAT_2; HEAT repeats
      pfam16186
      Location:382 → 421
      Arm_3; Atypical Arm repeat
      sd00044
      Location:14 → 39
      HEAT; HEAT repeat [structural motif]
      sd00043
      Location:172 → 197
      ARM; armadillo repeat [structural motif]
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9FJ92.1

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