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    Protein phosphatase 2C family protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 832860, updated on 18-Sep-2024

    Summary

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    Official Full Name
    Protein phosphatase 2C family protein
    Primary source
    TAIR:AT5G27930
    Locus tag
    AT5G27930
    See related
    Araport:AT5G27930
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    F15F15.3
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    Genomic context

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    Location:
    chromosome: 5
    Exon count:
    6
    Sequence:
    Chromosome: 5; NC_003076.8 (9957816..9961374, complement)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene pseudo Neighboring gene ncRNA Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. EGR2 phosphatase regulates OST1 kinase activity and freezing tolerance in Arabidopsis. Ding Y, et al. EMBO J, 2019 Jan 3. PMID 30429206, Free PMC Article
    2. Spatial differences in stoichiometry of EGR phosphatase and Microtubule-associated Stress Protein 1 control root meristem activity during drought stress. Longkumer T, et al. Plant Cell, 2022 Feb 3. PMID 34865106, Free PMC Article
    3. Protein Phosphatase 2Cs and Microtubule-Associated Stress Protein 1 Control Microtubule Stability, Plant Growth, and Drought Response. Bhaskara GB, et al. Plant Cell, 2017 Jan. PMID 28011693, Free PMC Article
    4. Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana. Tabata S, et al. Nature, 2000 Dec 14. PMID 11130714

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Spatial differences in stoichiometry of EGR phosphatase and Microtubule-associated Stress Protein 1 control root meristem activity during drought stress.
      Title: Spatial differences in stoichiometry of EGR phosphatase and Microtubule-associated Stress Protein 1 control root meristem activity during drought stress.
    2. A molecular mechanism underlying cold activation of OST1 by membrane-localized EGR2 and this suggests a myristoyl switch on EGR2 helps plants to adapt to cold stress.
      Title: EGR2 phosphatase regulates OST1 kinase activity and freezing tolerance in Arabidopsis.
    3. The EGR (clade E growth-regulating (EGR) type 2C protein phosphatases)-MASP1 (microtubule-associated stress protein 1 (MASP1; AT4G03260) system selectively regulates microtubule recovery and stability to adjust plant growth and cell expansion in response to changing environmental conditions.
      Title: Protein Phosphatase 2Cs and Microtubule-Associated Stress Protein 1 Control Microtubule Stability, Plant Growth, and Drought Response.
    Submit: New GeneRIF Correction

    General gene information

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    NM_001344046.1
    NM_122675.4
    NM_180755.2

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables myosin phosphatase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables protein serine/threonine phosphatase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within drought recovery IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within microtubule cytoskeleton organization IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within negative regulation of growth IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within protein dephosphorylation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm ISM
    Inferred from Sequence Model
    more info
    		  
    located_in plasma membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    Protein phosphatase 2C family protein
    NP_568503.1
    • Protein phosphatase 2C family protein; FUNCTIONS IN: protein serine/threonine phosphatase activity, catalytic activity; INVOLVED IN: biological_process unknown; LOCATED IN: cellular_component unknown; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Protein phosphatase 2C-related (InterPro:IPR001932), Protein phosphatase 2C (InterPro:IPR015655), Protein phosphatase 2C, N-terminal (InterPro:IPR014045); BEST Arabidopsis thaliana protein match is: Protein phosphatase 2C family protein (TAIR:AT3G05640.2); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).
    NP_851086.1
    • Protein phosphatase 2C family protein; FUNCTIONS IN: protein serine/threonine phosphatase activity, catalytic activity; INVOLVED IN: biological_process unknown; LOCATED IN: cellular_component unknown; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Protein phosphatase 2C-related (InterPro:IPR001932), Protein phosphatase 2C (InterPro:IPR015655), Protein phosphatase 2C, N-terminal (InterPro:IPR014045); BEST Arabidopsis thaliana protein match is: Protein phosphatase 2C family protein (TAIR:AT3G05640.2); Has 5854 Blast hits to 5851 proteins in 292 species: Archae - 2; Bacteria - 6; Metazoa - 1439; Fungi - 687; Plants - 2519; Viruses - 5; Other Eukaryotes - 1196 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      9957816..9961374 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_122675.4 → NP_568503.1  Protein phosphatase 2C family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_568503.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q0WM64, Q0WRB2, Q8GX49, Q8LD08, Q8SBC4
      UniProtKB/TrEMBL
      A0A7G2FD10
      Conserved Domains (1) summary
      cd00143
      Location:62 → 353
      PP2Cc; Serine/threonine phosphatases, family 2C, catalytic domain; The protein architecture and deduced catalytic mechanism of PP2C phosphatases are similar to the PP1, PP2A, PP2B family of protein Ser/Thr phosphatases, with which PP2C shares no sequence ...

    2. NM_001344046.1 → NP_001332736.1  Protein phosphatase 2C family protein [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1R7T3I5, A0A7G2FD10
      Conserved Domains (1) summary
      cd00143
      Location:62 → 301
      PP2Cc; Serine/threonine phosphatases, family 2C, catalytic domain; The protein architecture and deduced catalytic mechanism of PP2C phosphatases are similar to the PP1, PP2A, PP2B family of protein Ser/Thr phosphatases, with which PP2C shares no sequence ...

    3. NM_180755.2 → NP_851086.1  Protein phosphatase 2C family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_851086.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q0WM64, Q0WRB2, Q8GX49, Q8LD08, Q8SBC4
      UniProtKB/TrEMBL
      A0A7G2FD10
      Conserved Domains (1) summary
      cd00143
      Location:62 → 353
      PP2Cc; Serine/threonine phosphatases, family 2C, catalytic domain; The protein architecture and deduced catalytic mechanism of PP2C phosphatases are similar to the PP1, PP2A, PP2B family of protein Ser/Thr phosphatases, with which PP2C shares no sequence ...
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q0WRB2.1

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