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    pigm-1 GPI mannosyltransferase 1 [ Caenorhabditis elegans ]

    Gene ID: 174736, updated on 9-Dec-2024

    Summary

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    Official Symbol
    pigm-1
    Official Full Name
    GPI mannosyltransferase 1
    Primary source
    WormBase:WBGene00007189
    Locus tag
    CELE_B0491.1
    See related
    AllianceGenome:WB:WBGene00007189
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable mannosyltransferase activity. Predicted to be involved in GPI anchor biosynthetic process. Predicted to be located in endoplasmic reticulum membrane. Predicted to be part of glycosylphosphatidylinositol-mannosyltransferase I complex. Orthologous to human PIGM (phosphatidylinositol glycan anchor biosynthesis class M). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See pigm-1 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    5
    Sequence:
    Chromosome: II; NC_003280.10 (11348445..11350057)

    Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene Complex I-B14.7 Neighboring gene DNA helicase Neighboring gene diphthine methyl ester synthase Neighboring gene Chloride channel protein Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003280.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
    2. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article
    3. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables alpha-1,4-mannosyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables glycolipid mannosyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables glycosyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables mannosyltransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in GPI anchor biosynthetic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in GPI anchor biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in GPI anchor metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in endoplasmic reticulum IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in endoplasmic reticulum membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of glycosylphosphatidylinositol-mannosyltransferase I complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    GPI mannosyltransferase 1
    NP_496426.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003280.10 Reference assembly

      Range
      11348445..11350057
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_064025.6 → NP_496426.1  GPI mannosyltransferase 1 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_496426.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q17515
      Conserved Domains (1) summary
      pfam05007
      Location:146 → 405
      Mannosyl_trans; Mannosyltransferase (PIG-M)
    Nucleotide Protein
    Heading Accession and Version

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