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These reference sequences exist independently of genome builds. Explain
These reference sequences are curated independently of the genome
annotation cycle, so their versions may not match the RefSeq versions in the current
genome build. Identify version mismatches by comparing the version of the RefSeq in
this section to the one reported in Genomic regions,
transcripts, and products above.
mRNA and Protein(s)
-
NM_001042600.3 → NP_001036065.1 mitogen-activated protein kinase kinase kinase kinase 1 isoform 1
See identical proteins and their annotated locations for NP_001036065.1
Status: VALIDATED
- Description
- Transcript Variant: This variant (1) lacks an exon in the 3' coding region, which results in a frameshift, compared to variant 2. The encoded isoform (1) has a shorter and distinct C-terminus, compared to isoform 2.
- Source sequence(s)
-
HY074876, U66464
- Consensus CDS
-
CCDS42564.1
- UniProtKB/TrEMBL
-
K7ER95
- Related
- ENSP00000380066.1, ENST00000396857.7
- Conserved Domains (3) summary
-
- smart00036
Location:500 → 807
- CNH; Domain found in NIK1-like kinases, mouse citron and yeast ROM1, ROM2
- smart00220
Location:17 → 274
- S_TKc; Serine/Threonine protein kinases, catalytic domain
- cd06613
Location:16 → 274
- STKc_MAP4K3_like; Catalytic domain of Mitogen-activated protein kinase kinase kinase kinase (MAP4K) 3-like Serine/Threonine Kinases
-
NM_007181.6 → NP_009112.1 mitogen-activated protein kinase kinase kinase kinase 1 isoform 2
See identical proteins and their annotated locations for NP_009112.1
Status: VALIDATED
- Description
- Transcript Variant: This variant (2) represents the longer transcript and encodes the longer isoform (2).
- Source sequence(s)
-
HY074876, U66464
- Consensus CDS
-
CCDS59385.1
- UniProtKB/Swiss-Prot
-
Q92918
- UniProtKB/TrEMBL
-
K7ER95
- Related
- ENSP00000465039.1, ENST00000591517.5
- Conserved Domains (3) summary
-
- smart00036
Location:500 → 807
- CNH; Domain found in NIK1-like kinases, mouse citron and yeast ROM1, ROM2
- smart00220
Location:17 → 274
- S_TKc; Serine/Threonine protein kinases, catalytic domain
- cd06613
Location:16 → 274
- STKc_MAP4K3_like; Catalytic domain of Mitogen-activated protein kinase kinase kinase kinase (MAP4K) 3-like Serine/Threonine Kinases
The following sections contain reference sequences that belong to a
specific genome build. Explain
This section includes genomic Reference
Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as
RefSeqs for chromosomes and scaffolds (contigs) from both reference and alternate
assemblies. Model RNAs and proteins are also reported here.
Reference GRCh38.p14 Primary Assembly
Genomic
-
NC_000019.10 Reference GRCh38.p14 Primary Assembly
- Range
-
38587641..38617953 complement
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
XM_011526404.2 → XP_011524706.1 mitogen-activated protein kinase kinase kinase kinase 1 isoform X1
- UniProtKB/TrEMBL
-
K7ER95
- Conserved Domains (3) summary
-
- smart00036
Location:540 → 847
- CNH; Domain found in NIK1-like kinases, mouse citron and yeast ROM1, ROM2
- smart00220
Location:17 → 274
- S_TKc; Serine/Threonine protein kinases, catalytic domain
- cd06613
Location:16 → 274
- STKc_MAP4K3_like; Catalytic domain of Mitogen-activated protein kinase kinase kinase kinase (MAP4K) 3-like Serine/Threonine Kinases
Reference GRCh38.p14 PATCHES
Genomic
-
NW_014040929.1 Reference GRCh38.p14 PATCHES
- Range
-
1476..27589 complement
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
Alternate T2T-CHM13v2.0
Genomic
-
NC_060943.1 Alternate T2T-CHM13v2.0
- Range
-
41391622..41421931 complement
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
XM_054319680.1 → XP_054175655.1 mitogen-activated protein kinase kinase kinase kinase 1 isoform X1
- UniProtKB/TrEMBL
-
K7ER95
-
XM_054319681.1 → XP_054175656.1 mitogen-activated protein kinase kinase kinase kinase 1 isoform X2
- UniProtKB/TrEMBL
-
K7ER95
-
XM_054319682.1 → XP_054175657.1 mitogen-activated protein kinase kinase kinase kinase 1 isoform X3
- UniProtKB/TrEMBL
-
K7ER95