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    FRS2 fibroblast growth factor receptor substrate 2 [ Homo sapiens (human) ]

    Gene ID: 10818, updated on 10-Dec-2024

    Summary

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    Official Symbol
    FRS2provided by HGNC
    Official Full Name
    fibroblast growth factor receptor substrate 2provided by HGNC
    Primary source
    HGNC:HGNC:16971
    See related
    Ensembl:ENSG00000166225 MIM:607743; AllianceGenome:HGNC:16971
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    SNT; SNT1; FRS1A; FRS2A; SNT-1; FRS2alpha
    Summary
    Enables fibroblast growth factor receptor binding activity and neurotrophin TRKA receptor binding activity. Involved in negative regulation of cardiac muscle cell differentiation. Acts upstream of or within fibroblast growth factor receptor signaling pathway. Located in adherens junction. Biomarker of renal cell carcinoma. [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Ubiquitous expression in thyroid (RPKM 6.6), endometrium (RPKM 6.6) and 25 other tissues See more
    Orthologs
    mouse all
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    Genomic context

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    See FRS2 in Genome Data Viewer
    Location:
    12q15
    Exon count:
    19
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 12 NC_000012.12 (69470388..69579793)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 12 NC_060936.1 (69449328..69558701)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 12 NC_000012.11 (69864168..69973573)

    Chromosome 12 - NC_000012.12Genomic Context describing neighboring genes Neighboring gene YEATS domain containing 4 Neighboring gene ribosomal protein S26 pseudogene 45 Neighboring gene long intergenic non-protein coding RNA 2373 Neighboring gene OCT4-NANOG-H3K4me1 hESC enhancer GRCh37_chr12:69860555-69861168 Neighboring gene H3K27ac hESC enhancer GRCh37_chr12:69863839-69864340 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 6651 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 6652 Neighboring gene MPRA-validated peak1784 silencer Neighboring gene small nucleolar RNA, H/ACA box 113 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 6653 Neighboring gene microRNA 3913-1 Neighboring gene microRNA 3913-2 Neighboring gene chaperonin containing TCP1 subunit 2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Bibliography

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    Related articles in PubMed

    1. FGF-receptor substrate 2 functions as a molecular sensor integrating external regulatory signals into the FGF pathway. Zhou W, et al. Cell Res, 2009 Oct. PMID 19652666
    2. Pharmacologically targeting the myristoylation of the scaffold protein FRS2α inhibits FGF/FGFR-mediated oncogenic signaling and tumor progression. Li Q, et al. J Biol Chem, 2018 Apr 27. PMID 29540482, Free PMC Article
    3. Expression of fibroblast growth factor receptor substrate 2 (FRS2) in primary retroperitoneal liposarcoma and its clinical implications. Chen WD, et al. Eur Rev Med Pharmacol Sci, 2023 Jul. PMID 37458641
    4. FGF signaling contributes to atherosclerosis by enhancing the inflammatory response in vascular smooth muscle cells. Qi M, et al. Mol Med Rep, 2019 Jul. PMID 31115530, Free PMC Article
    5. High-resolution genomic mapping reveals consistent amplification of the fibroblast growth factor receptor substrate 2 gene in well-differentiated and dedifferentiated liposarcoma. Wang X, et al. Genes Chromosomes Cancer, 2011 Nov. PMID 21793095

    See all (123) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. FRS2 regulated by miR-429 and miR-206 promotes angiogenesis in osteosarcoma.
      Title: FRS2 regulated by miR-429 and miR-206 promotes angiogenesis in osteosarcoma.
    2. Over-expression of microRNA-145 Elevating Autophagy Activities via Downregulating FRS2 Expression.
      Title: Over-expression of microRNA-145 Elevating Autophagy Activities via Downregulating FRS2 Expression.
    3. Expression of fibroblast growth factor receptor substrate 2 (FRS2) in primary retroperitoneal liposarcoma and its clinical implications.
      Title: Expression of fibroblast growth factor receptor substrate 2 (FRS2) in primary retroperitoneal liposarcoma and its clinical implications.
    4. Hsa_circ_0093741 competes with FRS2 for miR-562 binding sites to promote nephroblastoma progression.
      Title: Hsa_circ_0093741 competes with FRS2 for miR-562 binding sites to promote nephroblastoma progression.
    5. Expression of FRS2 in atypical lipomatous tumor/well-differentiated liposarcoma and dedifferentiated liposarcoma: an immunohistochemical analysis of 182 cases with genetic data.
      Title: Expression of FRS2 in atypical lipomatous tumor/well-differentiated liposarcoma and dedifferentiated liposarcoma: an immunohistochemical analysis of 182 cases with genetic data.
    6. Circular RNA circUBR4 regulates ox-LDL-induced proliferation and migration of vascular smooth muscle cells through miR-185-5p/FRS2 axis.
      Title: Circular RNA circUBR4 regulates ox-LDL-induced proliferation and migration of vascular smooth muscle cells through miR-185-5p/FRS2 axis.
    7. Long non-coding RNA (lncRNA) nuclear enriched abundant transcript 1 (NEAT1) regulates fibroblast growth factor receptor substrate 2 (FRS2) by targeting microRNA (miR)-29-3p in hypertrophic scar fibroblasts.
      Title: Long non-coding RNA (lncRNA) nuclear enriched abundant transcript 1 (NEAT1) regulates fibroblast growth factor receptor substrate 2 (FRS2) by targeting microRNA (miR)-29-3p in hypertrophic scar fibroblasts.
    8. Upregulation of lncRNA ZFAS1 promotes lung adenocarcinoma progression by sponging miR-1271-5p and upregulating FRS2.
      Title: Upregulation of lncRNA ZFAS1 promotes lung adenocarcinoma progression by sponging miR-1271-5p and upregulating FRS2.
    9. LncRNA ANRIL regulates cell proliferation and migration via sponging miR-339-5p and regulating FRS2 expression in atherosclerosis.
      Title: LncRNA ANRIL regulates cell proliferation and migration via sponging miR-339-5p and regulating FRS2 expression in atherosclerosis.
    10. MiR-140-5p and miR-92a-3p suppress the cell proliferation, migration and invasion and promoted apoptosis in Wilms' tumor by targeting FRS2.
      Title: MiR-140-5p and miR-92a-3p suppress the cell proliferation, migration and invasion and promoted apoptosis in Wilms' tumor by targeting FRS2.
    Submit: New GeneRIF Correction See all GeneRIFs (42)

    Phenotypes

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    Review eQTL and phenotype association data in this region using PheGenI

    EBI GWAS Catalog

    Description
    Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.
    EBI GWAS Catalog
    Genomic association analysis suggests chromosome 12 locus influencing antihypertensive response to thiazide diuretic.
    EBI GWAS Catalog
    Hundreds of variants clustered in genomic loci and biological pathways affect human height.
    EBI GWAS Catalog
    Many sequence variants affecting diversity of adult human height.
    EBI GWAS Catalog
    Meta-analysis of genome-wide association studies of adult height in East Asians identifies 17 novel loci.
    EBI GWAS Catalog

    Variation

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    See variants in ClinVar

    See studies and variants in dbVar

    See Variation Viewer (GRCh37.p13)

    See Variation Viewer (GRCh38)

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    • D12S1680 (e-PCR), detects polymorphism

    Homology

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    enables fibroblast growth factor receptor binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables fibroblast growth factor receptor binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables neurotrophin TRKA receptor binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables phosphatase activator activity TAS
    Traceable Author Statement
    more info
    		 PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables transmembrane receptor protein tyrosine kinase adaptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables transmembrane receptor protein tyrosine kinase adaptor activity TAS
    Traceable Author Statement
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in G protein-coupled receptor signaling pathway TAS
    Traceable Author Statement
    more info
    		 PubMed 
    involved_in anterior/posterior axis specification, embryo IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in cell surface receptor protein tyrosine phosphatase signaling pathway TAS
    Traceable Author Statement
    more info
    		 PubMed 
    involved_in fibroblast growth factor receptor signaling pathway IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    acts_upstream_of_or_within fibroblast growth factor receptor signaling pathway IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    involved_in fibroblast growth factor receptor signaling pathway TAS
    Traceable Author Statement
    more info
    		 PubMed 
    involved_in forebrain development IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in gastrulation with mouth forming second IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in lens fiber cell development IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in lens placode formation involved in camera-type eye formation IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in negative regulation of cardiac muscle cell differentiation IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    involved_in neuroblast proliferation IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in organ induction IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in positive regulation of MAPK cascade IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in positive regulation of vascular associated smooth muscle cell proliferation IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in regulation of ERK1 and ERK2 cascade IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in regulation of apoptotic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in regulation of epithelial cell proliferation IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in ventricular septum development IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in adherens junction IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in cell-cell junction IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in cytosol TAS
    Traceable Author Statement
    more info
    		  
    located_in endomembrane system IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in membrane TAS
    Traceable Author Statement
    more info
    		 PubMed 
    located_in plasma membrane TAS
    Traceable Author Statement
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    fibroblast growth factor receptor substrate 2
    Names
    FGFR signalling adaptor
    FGFR substrate 2
    FGFR-signaling adaptor SNT
    epididymis secretory sperm binding protein
    suc1-associated neurotrophic factor target 1

    NCBI Reference Sequences (RefSeq)

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    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001042555.3 → NP_001036020.1  fibroblast growth factor receptor substrate 2

      See identical proteins and their annotated locations for NP_001036020.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) has multiple differences in the 5' UTR, compared to variant 3. All variants encode the same protein.
      Source sequence(s)
      AC018921, BC021562, BP363404, CD677411, DA311708
      Consensus CDS
      CCDS41809.1
      UniProtKB/Swiss-Prot
      B0LPF2, B2R684, O43558, Q7LDQ6, Q8WU20
      UniProtKB/TrEMBL
      A0A384NQ31, L7RTG7
      Conserved Domains (1) summary
      cd01202
      Location:15 → 106
      PTB_FRS2; Fibroblast growth factor receptor substrate 2 phosphotyrosine-binding domain

    2. NM_001278351.2 → NP_001265280.1  fibroblast growth factor receptor substrate 2

      See identical proteins and their annotated locations for NP_001265280.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) represents the longest transcript. All variants encode the same protein.
      Source sequence(s)
      AC018921, BC021562, CD677411, DA189114, DR003634
      Consensus CDS
      CCDS41809.1
      UniProtKB/Swiss-Prot
      B0LPF2, B2R684, O43558, Q7LDQ6, Q8WU20
      UniProtKB/TrEMBL
      A0A384NQ31, L7RTG7
      Conserved Domains (1) summary
      cd01202
      Location:15 → 106
      PTB_FRS2; Fibroblast growth factor receptor substrate 2 phosphotyrosine-binding domain

    3. NM_001278353.2 → NP_001265282.1  fibroblast growth factor receptor substrate 2

      See identical proteins and their annotated locations for NP_001265282.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (4) has multiple differences in the 5' UTR, compared to variant 3. All variants encode the same protein.
      Source sequence(s)
      AC018921, BC021562, BP230333, BU166503, CD677411, DA189114, DA311708
      Consensus CDS
      CCDS41809.1
      UniProtKB/Swiss-Prot
      B0LPF2, B2R684, O43558, Q7LDQ6, Q8WU20
      UniProtKB/TrEMBL
      A0A384NQ31, L7RTG7
      Conserved Domains (1) summary
      cd01202
      Location:15 → 106
      PTB_FRS2; Fibroblast growth factor receptor substrate 2 phosphotyrosine-binding domain

    4. NM_001278354.2 → NP_001265283.1  fibroblast growth factor receptor substrate 2

      See identical proteins and their annotated locations for NP_001265283.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (5) lacks an exon in the 5' UTR, compared to variant 3. All variants encode the same protein.
      Source sequence(s)
      AC018921, BC021562, CD677411, DA189114, DA721439, DR003634
      Consensus CDS
      CCDS41809.1
      UniProtKB/Swiss-Prot
      B0LPF2, B2R684, O43558, Q7LDQ6, Q8WU20
      UniProtKB/TrEMBL
      A0A384NQ31, L7RTG7
      Conserved Domains (1) summary
      cd01202
      Location:15 → 106
      PTB_FRS2; Fibroblast growth factor receptor substrate 2 phosphotyrosine-binding domain

    5. NM_001278355.2 → NP_001265284.1  fibroblast growth factor receptor substrate 2

      See identical proteins and their annotated locations for NP_001265284.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (6) has multiple differences in the 5' UTR, compared to variant 3. All variants encode the same protein.
      Source sequence(s)
      AC018921, AK312477, BP311537, CD677411, DA311708, DB081843
      Consensus CDS
      CCDS41809.1
      UniProtKB/Swiss-Prot
      B0LPF2, B2R684, O43558, Q7LDQ6, Q8WU20
      UniProtKB/TrEMBL
      A0A384NQ31, L7RTG7
      Conserved Domains (1) summary
      cd01202
      Location:15 → 106
      PTB_FRS2; Fibroblast growth factor receptor substrate 2 phosphotyrosine-binding domain

    6. NM_001278356.2 → NP_001265285.1  fibroblast growth factor receptor substrate 2

      See identical proteins and their annotated locations for NP_001265285.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (7) lacks two exons in the 5' UTR, compared to variant 3. All variants encode the same protein.
      Source sequence(s)
      AC018921, AK312477, BP363404, CD677411, DA311708
      Consensus CDS
      CCDS41809.1
      UniProtKB/Swiss-Prot
      B0LPF2, B2R684, O43558, Q7LDQ6, Q8WU20
      UniProtKB/TrEMBL
      A0A384NQ31, L7RTG7
      Related
      ENSP00000450048.1, ENST00000549921.6
      Conserved Domains (1) summary
      cd01202
      Location:15 → 106
      PTB_FRS2; Fibroblast growth factor receptor substrate 2 phosphotyrosine-binding domain

    7. NM_001278357.2 → NP_001265286.1  fibroblast growth factor receptor substrate 2

      See identical proteins and their annotated locations for NP_001265286.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (8) lacks four exons in the 5' UTR, compared to variant 3. All variants encode the same protein.
      Source sequence(s)
      AC018921, AK312477, BC021562, CD677411, DA189114, DA311708
      Consensus CDS
      CCDS41809.1
      UniProtKB/Swiss-Prot
      B0LPF2, B2R684, O43558, Q7LDQ6, Q8WU20
      UniProtKB/TrEMBL
      A0A384NQ31, L7RTG7
      Related
      ENSP00000447241.1, ENST00000550389.5
      Conserved Domains (1) summary
      cd01202
      Location:15 → 106
      PTB_FRS2; Fibroblast growth factor receptor substrate 2 phosphotyrosine-binding domain

    8. NM_006654.5 → NP_006645.3  fibroblast growth factor receptor substrate 2

      See identical proteins and their annotated locations for NP_006645.3

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) lacks an exon in the 5' UTR, compared to variant 3. All variants encode the same protein.
      Source sequence(s)
      AC018921, BC021562, BP230333, BP363404, CD677411, DA311708
      Consensus CDS
      CCDS41809.1
      UniProtKB/Swiss-Prot
      B0LPF2, B2R684, O43558, Q7LDQ6, Q8WU20
      UniProtKB/TrEMBL
      A0A384NQ31, L7RTG7
      Conserved Domains (1) summary
      cd01202
      Location:15 → 106
      PTB_FRS2; Fibroblast growth factor receptor substrate 2 phosphotyrosine-binding domain

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000012.12 Reference GRCh38.p14 Primary Assembly

      Range
      69470388..69579793
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017018718.2 → XP_016874207.1  fibroblast growth factor receptor substrate 2 isoform X1

      UniProtKB/Swiss-Prot
      B0LPF2, B2R684, O43558, Q7LDQ6, Q8WU20
      UniProtKB/TrEMBL
      A0A384NQ31, L7RTG7
      Conserved Domains (1) summary
      cd01202
      Location:15 → 106
      PTB_FRS2; Fibroblast growth factor receptor substrate 2 phosphotyrosine-binding domain

    2. XM_047428121.1 → XP_047284077.1  fibroblast growth factor receptor substrate 2 isoform X1

      UniProtKB/Swiss-Prot
      B0LPF2, B2R684, O43558, Q7LDQ6, Q8WU20
      UniProtKB/TrEMBL
      A0A384NQ31, L7RTG7

    3. XM_017018717.2 → XP_016874206.1  fibroblast growth factor receptor substrate 2 isoform X1

      UniProtKB/Swiss-Prot
      B0LPF2, B2R684, O43558, Q7LDQ6, Q8WU20
      UniProtKB/TrEMBL
      A0A384NQ31, L7RTG7
      Conserved Domains (1) summary
      cd01202
      Location:15 → 106
      PTB_FRS2; Fibroblast growth factor receptor substrate 2 phosphotyrosine-binding domain

    4. XM_047428118.1 → XP_047284074.1  fibroblast growth factor receptor substrate 2 isoform X1

      UniProtKB/Swiss-Prot
      B0LPF2, B2R684, O43558, Q7LDQ6, Q8WU20
      UniProtKB/TrEMBL
      A0A384NQ31, L7RTG7

    5. XM_047428122.1 → XP_047284078.1  fibroblast growth factor receptor substrate 2 isoform X1

      UniProtKB/Swiss-Prot
      B0LPF2, B2R684, O43558, Q7LDQ6, Q8WU20
      UniProtKB/TrEMBL
      A0A384NQ31, L7RTG7

    6. XM_047428119.1 → XP_047284075.1  fibroblast growth factor receptor substrate 2 isoform X1

      UniProtKB/Swiss-Prot
      B0LPF2, B2R684, O43558, Q7LDQ6, Q8WU20
      UniProtKB/TrEMBL
      A0A384NQ31, L7RTG7

    7. XM_047428120.1 → XP_047284076.1  fibroblast growth factor receptor substrate 2 isoform X1

      UniProtKB/Swiss-Prot
      B0LPF2, B2R684, O43558, Q7LDQ6, Q8WU20
      UniProtKB/TrEMBL
      A0A384NQ31, L7RTG7

    8. XM_047428123.1 → XP_047284079.1  fibroblast growth factor receptor substrate 2 isoform X1

      UniProtKB/Swiss-Prot
      B0LPF2, B2R684, O43558, Q7LDQ6, Q8WU20
      UniProtKB/TrEMBL
      A0A384NQ31, L7RTG7

    9. XM_017018719.2 → XP_016874208.1  fibroblast growth factor receptor substrate 2 isoform X1

      UniProtKB/Swiss-Prot
      B0LPF2, B2R684, O43558, Q7LDQ6, Q8WU20
      UniProtKB/TrEMBL
      A0A384NQ31, L7RTG7
      Conserved Domains (1) summary
      cd01202
      Location:15 → 106
      PTB_FRS2; Fibroblast growth factor receptor substrate 2 phosphotyrosine-binding domain

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060936.1 Alternate T2T-CHM13v2.0

      Range
      69449328..69558701
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_054370826.1 → XP_054226801.1  fibroblast growth factor receptor substrate 2 isoform X1

      UniProtKB/Swiss-Prot
      B0LPF2, B2R684, O43558, Q7LDQ6, Q8WU20
      UniProtKB/TrEMBL
      A0A384NQ31, L7RTG7

    2. XM_054370830.1 → XP_054226805.1  fibroblast growth factor receptor substrate 2 isoform X1

      UniProtKB/Swiss-Prot
      B0LPF2, B2R684, O43558, Q7LDQ6, Q8WU20
      UniProtKB/TrEMBL
      A0A384NQ31, L7RTG7

    3. XM_054370824.1 → XP_054226799.1  fibroblast growth factor receptor substrate 2 isoform X1

      UniProtKB/Swiss-Prot
      B0LPF2, B2R684, O43558, Q7LDQ6, Q8WU20
      UniProtKB/TrEMBL
      A0A384NQ31, L7RTG7

    4. XM_054370825.1 → XP_054226800.1  fibroblast growth factor receptor substrate 2 isoform X1

      UniProtKB/Swiss-Prot
      B0LPF2, B2R684, O43558, Q7LDQ6, Q8WU20
      UniProtKB/TrEMBL
      A0A384NQ31, L7RTG7

    5. XM_054370831.1 → XP_054226806.1  fibroblast growth factor receptor substrate 2 isoform X1

      UniProtKB/Swiss-Prot
      B0LPF2, B2R684, O43558, Q7LDQ6, Q8WU20
      UniProtKB/TrEMBL
      A0A384NQ31, L7RTG7

    6. XM_054370827.1 → XP_054226802.1  fibroblast growth factor receptor substrate 2 isoform X1

      UniProtKB/Swiss-Prot
      B0LPF2, B2R684, O43558, Q7LDQ6, Q8WU20
      UniProtKB/TrEMBL
      A0A384NQ31, L7RTG7

    7. XM_054370828.1 → XP_054226803.1  fibroblast growth factor receptor substrate 2 isoform X1

      UniProtKB/Swiss-Prot
      B0LPF2, B2R684, O43558, Q7LDQ6, Q8WU20
      UniProtKB/TrEMBL
      A0A384NQ31, L7RTG7

    8. XM_054370832.1 → XP_054226807.1  fibroblast growth factor receptor substrate 2 isoform X1

      UniProtKB/Swiss-Prot
      B0LPF2, B2R684, O43558, Q7LDQ6, Q8WU20
      UniProtKB/TrEMBL
      A0A384NQ31, L7RTG7

    9. XM_054370829.1 → XP_054226804.1  fibroblast growth factor receptor substrate 2 isoform X1

      UniProtKB/Swiss-Prot
      B0LPF2, B2R684, O43558, Q7LDQ6, Q8WU20
      UniProtKB/TrEMBL
      A0A384NQ31, L7RTG7
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8WU20.4 GenPept UniProtKB/Swiss-Prot:Q8WU20

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