GGT3P gamma-glutamyltransferase 3 pseudogene [Homo sapiens (human)] - Gene

Summary

Official Symbol: GGT3Pprovided by HGNC
Official Full Name: gamma-glutamyltransferase 3 pseudogeneprovided by HGNC
Primary source: HGNC:HGNC:4252
See related: Ensembl:ENSG00000197421 AllianceGenome:HGNC:4252
Gene type: pseudo
RefSeq status: VALIDATED
Organism: Homo sapiens
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as: GGT3
Summary: Predicted to enable glutathione hydrolase activity. Predicted to be involved in several processes, including glutathione catabolic process; leukotriene D4 biosynthetic process; and peptide modification. Located in extracellular exosome. [provided by Alliance of Genome Resources, Dec 2024]
Expression: Biased expression in kidney (RPKM 10.5), small intestine (RPKM 4.5) and 12 other tissues See more
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Genomic context

Location:: 22q11.21

Exon count:: 13

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCh38.p14 (GCF_000001405.40)	22	NC_000022.11 (18773689..18791961, complement)
RS_2024_08	current	T2T-CHM13v2.0 (GCF_009914755.1)	22	NC_060946.1 (19147114..19165401, complement)
RS_2024_09	previous assembly	GRCh37.p13 (GCF_000001405.25)	22	NC_000022.10 (18761202..18779474, complement)

Chromosome 22 - NC_000022.11 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Tissue-specific circular RNA induction during human fetal development
Description: 35 human fetal samples from 6 tissues (3 - 7 replicates per tissue) collected between 10 and 20 weeks gestational time were sequenced using Illumina TruSeq Stranded Total RNA
BioProject: PRJNA270632
Publication: PMID 26076956
Analysis date: Mon Apr 2 22:54:59 2018

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

General gene information

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Markers

J05235 (e-PCR)
- UniSTS:31837

RH69116 (e-PCR)
- UniSTS:79980

D22S732 (e-PCR)
- UniSTS:42929

RH79893 (e-PCR)
- UniSTS:87241

GDB:190922 (e-PCR)
- UniSTS:155632

NoName (e-PCR)
- UniSTS:485874

Gene Ontology Provided by GOA

Function	Evidence Code	Pubs
enables glutathione hydrolase activity	IBA Inferred from Biological aspect of Ancestor more info
enables leukotriene C4 gamma-glutamyl transferase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in glutathione biosynthetic process	IEA Inferred from Electronic Annotation more info
involved_in glutathione catabolic process	IBA Inferred from Biological aspect of Ancestor more info
involved_in leukotriene D4 biosynthetic process	ISS Inferred from Sequence or Structural Similarity more info
involved_in peptide modification	IBA Inferred from Biological aspect of Ancestor more info
involved_in proteolysis	IEA Inferred from Electronic Annotation more info
involved_in regulation of immune system process	IBA Inferred from Biological aspect of Ancestor more info
involved_in regulation of inflammatory response	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
located_in extracellular exosome	HDA more info	PubMed
is_active_in plasma membrane	IBA Inferred from Biological aspect of Ancestor more info

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.