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    SLC25A51 solute carrier family 25 member 51 [ Homo sapiens (human) ]

    Gene ID: 92014, updated on 10-Dec-2024

    Summary

    Official Symbol
    SLC25A51provided by HGNC
    Official Full Name
    solute carrier family 25 member 51provided by HGNC
    Primary source
    HGNC:HGNC:23323
    See related
    Ensembl:ENSG00000122696 MIM:619153; AllianceGenome:HGNC:23323
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    CG7943; MCART1
    Summary
    Enables NAD transmembrane transporter activity. Involved in mitochondrial NAD transmembrane transport. Located in mitochondrion. Is active in mitochondrial inner membrane. [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Ubiquitous expression in fat (RPKM 3.6), testis (RPKM 1.8) and 25 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See SLC25A51 in Genome Data Viewer
    Location:
    9p13.2-p13.1
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 9 NC_000009.12 (37877575..37904127, complement)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 9 NC_060933.1 (37901485..37928037, complement)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 9 NC_000009.11 (37877572..37904124, complement)

    Chromosome 9 - NC_000009.12Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105376037 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr9:37800323-37800924 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 19913 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 28404 Neighboring gene DDB1 and CUL4 associated factor 10 Neighboring gene mitochondrial ribosomal protein S10 pseudogene 5 Neighboring gene phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase pseudogene 1 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 19914 Neighboring gene thioredoxin related transmembrane protein 2 pseudogene 1 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 28405 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr9:37923197-37923808 Neighboring gene RNA, U7 small nuclear 124 pseudogene Neighboring gene SH2 domain containing adaptor protein B Neighboring gene H3K4me1 hESC enhancer GRCh37_chr9:37951849-37952348 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 28406 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 28407 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr9:37997675-37998176 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 28408 Neighboring gene Sharpr-MPRA regulatory region 5136 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr9:38008584-38009525 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr9:38010092-38010724 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 19915 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr9:38016883-38017646 Neighboring gene Sharpr-MPRA regulatory region 2787 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr9:38021463-38021972 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr9:38026045-38026553 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr9:38026554-38027063 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr9:38027064-38027572 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr9:38027573-38028081 Neighboring gene ReSE screen-validated silencer GRCh37_chr9:38028793-38028962 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr9:38030139-38030638 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr9:38032069-38032570 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr9:38037811-38038416 Neighboring gene VISTA enhancer hs2062 Neighboring gene P300/CBP strongly-dependent group 1 enhancer GRCh37_chr9:38047203-38048402 Neighboring gene H3K27ac hESC enhancer GRCh37_chr9:38048927-38049920 Neighboring gene CDK7 strongly-dependent group 2 enhancer GRCh37_chr9:38058891-38060090 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr9:38067661-38068464 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 19917 Neighboring gene uncharacterized LOC105376039

    Genomic regions, transcripts, and products

    Expression

    • Project title: Tissue-specific circular RNA induction during human fetal development
    • Description: 35 human fetal samples from 6 tissues (3 - 7 replicates per tissue) collected between 10 and 20 weeks gestational time were sequenced using Illumina TruSeq Stranded Total RNA
    • BioProject: PRJNA270632
    • Publication: PMID 26076956
    • Analysis date: Mon Apr 2 22:54:59 2018

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Interactions

    General gene information

    Clone Names

    • FLJ37273, MGC14836

    Gene Ontology Provided by GOA

    Component Evidence Code Pubs
    is_active_in mitochondrial inner membrane PubMed 
    located_in mitochondrion PubMed 
    is_active_in mitochondrion  
    located_in mitochondrion PubMed 

    General protein information

    Preferred Names
    mitochondrial nicotinamide adenine dinucleotide transporter SLC25A51
    Names
    mitochondrial NAD(+) transporter SLC25A51
    mitochondrial NAD+ transporter
    mitochondrial carrier triple repeat 1
    mitochondrial carrier triple repeat protein 1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_033412.4 → NP_219480.1  mitochondrial nicotinamide adenine dinucleotide transporter SLC25A51

      See identical proteins and their annotated locations for NP_219480.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the shortest transcript and encodes the functional protein.
      Source sequence(s)
      AL138752, BG953457
      Consensus CDS
      CCDS6614.1
      UniProtKB/Swiss-Prot
      Q9H1U9
      UniProtKB/TrEMBL
      B4DYA5
      Related
      ENSP00000242275.6, ENST00000242275.7
      Conserved Domains (1) summary
      pfam00153
      Location:31 → 112
      Mito_carr; Mitochondrial carrier protein

    RNA

    1. NR_024872.3 RNA Sequence

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) contains 3 alternate exons in the 5' and 3' regions and lacks the coding exon, compared to variant 1. This variant is represented as non-coding because it completely lacks the coding region found in variant 1.
      Source sequence(s)
      AK091407, AK098185, AL138752, KF459922
    2. NR_024873.3 RNA Sequence

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) contains 2 alternate exons at the 3' end and lacks the coding exon, compared to variant 1. This variant is represented as non-coding because it completely lacks the coding region found in variant 1.
      Source sequence(s)
      AK098185, AL138752, BC063563, KF459922

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000009.12 Reference GRCh38.p14 Primary Assembly

      Range
      37877575..37904127 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060933.1 Alternate T2T-CHM13v2.0

      Range
      37901485..37928037 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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