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    ST7-OT3 ST7 overlapping transcript 3 [ Homo sapiens (human) ]

    Gene ID: 93655, updated on 10-Dec-2024

    Summary

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    Official Symbol
    ST7-OT3provided by HGNC
    Official Full Name
    ST7 overlapping transcript 3provided by HGNC
    Primary source
    HGNC:HGNC:16045
    See related
    Ensembl:ENSG00000004866 AllianceGenome:HGNC:16045
    Gene type
    ncRNA
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    ST7; ST7OT3; NCRNA00026
    Expression
    Ubiquitous expression in thyroid (RPKM 6.6), lung (RPKM 6.3) and 25 other tissues See more
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    Genomic context

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    See ST7-OT3 in Genome Data Viewer
    Location:
    7q31.2
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 7 NC_000007.14 (117182681..117209937)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 7 NC_060931.1 (118498346..118525279)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 7 NC_000007.13 (116822735..116849991)

    Chromosome 7 - NC_000007.14Genomic Context describing neighboring genes Neighboring gene suppression of tumorigenicity 7 Neighboring gene MED14-independent group 3 enhancer GRCh37_chr7:116659304-116660503 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 26541 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 26542 Neighboring gene microRNA 6132 Neighboring gene H3K27ac hESC enhancer GRCh37_chr7:116716803-116717302 Neighboring gene greater CFTR locus negative regulatory element NR4 Neighboring gene uncharacterized LOC124901732 Neighboring gene ST7 antisense RNA 2 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 26543 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 26544 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr7:116794856-116795649 Neighboring gene greater CFTR locus negative regulatory element CR10 Neighboring gene greater CFTR locus negative regulatory element CR11 Neighboring gene uncharacterized LOC105375466 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 26545 Neighboring gene heterogeneous nuclear ribonucleoprotein A1 like 2 pseudogene Neighboring gene MT-ND2 pseudogene 37

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Tissue-specific circular RNA induction during human fetal development
    • Description: 35 human fetal samples from 6 tissues (3 - 7 replicates per tissue) collected between 10 and 20 weeks gestational time were sequenced using Illumina TruSeq Stranded Total RNA
    • BioProject: PRJNA270632
    • Publication: PMID 26076956
    • Analysis date: Mon Apr 2 22:54:59 2018

    Bibliography

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    Related articles in PubMed

    1. Chromosome 7q: where autism meets language disorder? Folstein SE, et al. Am J Hum Genet, 2000 Aug. PMID 10889044, Free PMC Article
    2. Identification of a novel gene on chromosome 7q31 that is interrupted by a translocation breakpoint in an autistic individual. Vincent JB, et al. Am J Hum Genet, 2000 Aug. PMID 10889047, Free PMC Article
    3. Recognition of unknown conserved alternatively spliced exons. Ohler U, et al. PLoS Comput Biol, 2005 Jul. PMID 16110330, Free PMC Article
    4. The RAY1/ST7 tumor-suppressor locus on chromosome 7q31 represents a complex multi-transcript system. Vincent JB, et al. Genomics, 2002 Sep. PMID 12213198
    5. Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing. Fei T, et al. Proc Natl Acad Sci U S A, 2017 Jun 27. PMID 28611215, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Phenotypes

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    Review eQTL and phenotype association data in this region using PheGenI

    Variation

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    See variants in ClinVar

    See studies and variants in dbVar

    See Variation Viewer (GRCh37.p13)

    See Variation Viewer (GRCh38)

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Other Names

    • ST7 overlapping transcript 3 (non-coding RNA)
    • ST7 overlapping transcript 3 (non-protein coding)
    • suppression of tumorigenicity 7

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    RNA

    1. NR_002332.2 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC002542, AF400044
      Related
      ENST00000543837.5

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000007.14 Reference GRCh38.p14 Primary Assembly

      Range
      117182681..117209937
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060931.1 Alternate T2T-CHM13v2.0

      Range
      118498346..118525279
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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