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    RERGL RERG like [ Homo sapiens (human) ]

    Gene ID: 79785, updated on 10-Dec-2024

    Summary

    Official Symbol
    RERGLprovided by HGNC
    Official Full Name
    RERG likeprovided by HGNC
    Primary source
    HGNC:HGNC:26213
    See related
    Ensembl:ENSG00000111404 AllianceGenome:HGNC:26213
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Summary
    Predicted to enable G protein activity and GTP binding activity. [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Broad expression in endometrium (RPKM 13.0), fat (RPKM 12.7) and 18 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See RERGL in Genome Data Viewer
    Location:
    12p12.3
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 12 NC_000012.12 (18080869..18090193, complement)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 12 NC_060936.1 (17957086..17966409, complement)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 12 NC_000012.11 (18233803..18243127, complement)

    Chromosome 12 - NC_000012.12Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC124902888 Neighboring gene uncharacterized LOC124902889 Neighboring gene VISTA enhancer hs579 Neighboring gene VISTA enhancer hs980 Neighboring gene microRNA 3974 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr12:18102760-18103303 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr12:18306612-18307209 Neighboring gene uncharacterized LOC124903122 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr12:18355246-18356201 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr12:18356202-18357156 Neighboring gene uncharacterized LOC124902890 Neighboring gene phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 gamma

    Genomic regions, transcripts, and products

    Expression

    • Project title: Tissue-specific circular RNA induction during human fetal development
    • Description: 35 human fetal samples from 6 tissues (3 - 7 replicates per tissue) collected between 10 and 20 weeks gestational time were sequenced using Illumina TruSeq Stranded Total RNA
    • BioProject: PRJNA270632
    • Publication: PMID 26076956
    • Analysis date: Mon Apr 2 22:54:59 2018

    General gene information

    Clone Names

    • FLJ22655

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    enables G protein activity  
    enables GTP binding  

    General protein information

    Preferred Names
    ras-related and estrogen-regulated growth inhibitor-like protein
    Names
    RERG/RAS-like
    NP_001273130.1
    NP_079006.1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    Genomic

    1. NG_052618.1 RefSeqGene

      Range
      5001..14325
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001286201.2NP_001273130.1  ras-related and estrogen-regulated growth inhibitor-like protein isoform b

      See identical proteins and their annotated locations for NP_001273130.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) differs in the 5' UTR, lacks a portion of the 5' coding region, and initiates translation at an alternate upstream start codon, compared to variant 1. The encoded isoform (b) has a distinct N-terminus and is shorter than isoform a.
      Source sequence(s)
      BC042888, BX422875, DT220095
      Consensus CDS
      CCDS66332.1
      UniProtKB/TrEMBL
      F5H686
      Related
      ENSP00000437814.1, ENST00000538724.6
      Conserved Domains (1) summary
      cd04146
      Location:5173
      RERG_RasL11_like; Ras-related and Estrogen-Regulated Growth inhibitor (RERG) and Ras-like 11 (RasL11)-like families
    2. NM_024730.4NP_079006.1  ras-related and estrogen-regulated growth inhibitor-like protein isoform a

      See identical proteins and their annotated locations for NP_079006.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (a).
      Source sequence(s)
      BC042888, DT220095
      Consensus CDS
      CCDS8679.1
      UniProtKB/Swiss-Prot
      Q9H628
      Related
      ENSP00000229002.2, ENST00000229002.6
      Conserved Domains (1) summary
      cd04146
      Location:6174
      RERG_RasL11_like; Ras-related and Estrogen-Regulated Growth inhibitor (RERG) and Ras-like 11 (RasL11)-like families

    RNA

    1. NR_104413.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AA220227, BC042888, BX422875, DT220095

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000012.12 Reference GRCh38.p14 Primary Assembly

      Range
      18080869..18090193 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060936.1 Alternate T2T-CHM13v2.0

      Range
      17957086..17966409 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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