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    Alyreffm10 Aly/REF export factor family member 10 [ Mus musculus (house mouse) ]

    Gene ID: 100043292, updated on 4-Jan-2025

    Summary

    Official Symbol
    Alyreffm10provided by MGI
    Official Full Name
    Aly/REF export factor family member 10provided by MGI
    Primary source
    MGI:MGI:3782524
    See related
    Ensembl:ENSMUSG00000090854 AllianceGenome:MGI:3782524
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Gm4340
    Summary
    Predicted to enable C5-methylcytidine-containing RNA reader activity and mRNA binding activity. Predicted to be involved in mRNA export from nucleus. Predicted to be located in cytoplasm. Predicted to be part of catalytic step 2 spliceosome; exon-exon junction complex; and transcription export complex. Predicted to be active in nucleus. Predicted to colocalize with chromosome, telomeric region. Orthologous to human ALYREF (Aly/REF export factor). [provided by Alliance of Genome Resources, Jan 2025]
    Expression
    Low expression observed in reference dataset See more
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    Genomic context

    See Alyreffm10 in Genome Data Viewer
    Location:
    10 D1; 10 54.72 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 10 NC_000076.7 (104029903..104032383)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 10 NC_000076.6 (104194042..104196522)

    Chromosome 10 - NC_000076.7Genomic Context describing neighboring genes Neighboring gene Aly/REF export factor family member 17 Neighboring gene Aly/REF export factor family member 15 Neighboring gene predicted gene, 22339 Neighboring gene microRNA 6411

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables C5-methylcytidine-containing RNA reader activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables mRNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Process Evidence Code Pubs
    involved_in RNA export from nucleus ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in mRNA export from nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in mRNA export from nucleus ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    part_of catalytic step 2 spliceosome ISO
    Inferred from Sequence Orthology
    more info
     
    colocalizes_with chromosome, telomeric region ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    part_of exon-exon junction complex ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
     
    part_of transcription export complex ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    RNA and export factor-binding protein 2-like

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001177535.1NP_001171006.1  RNA and export factor-binding protein 2-like

      Status: VALIDATED

      Source sequence(s)
      AC141428
      Consensus CDS
      CCDS88081.1
      UniProtKB/TrEMBL
      M0QWS9
      Related
      ENSMUSP00000137824.4, ENSMUST00000181615.8
      Conserved Domains (3) summary
      COG0724
      Location:79186
      RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
      cd12680
      Location:86160
      RRM_THOC4; RNA recognition motif in THO complex subunit 4 (THOC4) and similar proteins
      pfam07078
      Location:659
      FYTT; Forty-two-three protein

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000076.7 Reference GRCm39 C57BL/6J

      Range
      104029903..104032383
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017313746.1XP_017169235.1  RNA and export factor-binding protein 2-like isoform X1

      UniProtKB/TrEMBL
      M0QWB2, M0QWR4
      Conserved Domains (3) summary
      cd12680
      Location:86160
      RRM_THOC4; RNA recognition motif in THO complex subunit 4 (THOC4) and similar proteins
      TIGR01648
      Location:26179
      hnRNP-R-Q; heterogeneous nuclear ribonucleoprotein R, Q family
      pfam13865
      Location:169230
      FoP_duplication; C-terminal duplication domain of Friend of PRMT1
    2. XM_030244788.1XP_030100648.1  RNA and export factor-binding protein 2-like isoform X2

      UniProtKB/TrEMBL
      M0QWB2, M0QWR4
      Conserved Domains (3) summary
      cd12680
      Location:86160
      RRM_THOC4; RNA recognition motif in THO complex subunit 4 (THOC4) and similar proteins
      TIGR01648
      Location:26179
      hnRNP-R-Q; heterogeneous nuclear ribonucleoprotein R, Q family
      pfam13865
      Location:169229
      FoP_duplication; C-terminal duplication domain of Friend of PRMT1