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    Fhip1a FHF complex subunit HOOK interacting protein 1A [ Mus musculus (house mouse) ]

    Gene ID: 229488, updated on 27-Nov-2024

    Summary

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    Official Symbol
    Fhip1aprovided by MGI
    Official Full Name
    FHF complex subunit HOOK interacting protein 1Aprovided by MGI
    Primary source
    MGI:MGI:2444746
    See related
    Ensembl:ENSMUSG00000051000 AllianceGenome:MGI:2444746
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Fam160a1; 9930021J17Rik
    Summary
    Predicted to be involved in protein localization to perinuclear region of cytoplasm. Orthologous to human FHIP1A (FHF complex subunit HOOK interacting protein 1A). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Broad expression in mammary gland adult (RPKM 10.7), heart adult (RPKM 10.2) and 17 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Fhip1a in Genome Data Viewer
    Location:
    3 F1; 3 37.83 cM
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 3 NC_000069.7 (85567370..85653516, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 3 NC_000069.6 (85660063..85785302, complement)

    Chromosome 3 - NC_000069.7Genomic Context describing neighboring genes Neighboring gene predicted gene 3740 Neighboring gene STARR-positive B cell enhancer ABC_E6064 Neighboring gene predicted gene, 54168 Neighboring gene predicted gene, 46809 Neighboring gene glutamyl-tRNA amidotransferase subunit B Neighboring gene STARR-seq mESC enhancer starr_08111 Neighboring gene predicted gene, 40082 Neighboring gene STARR-seq mESC enhancer starr_08112 Neighboring gene proteasome (prosome, macropain) subunit, alpha type 1 pseudogene Neighboring gene STARR-seq mESC enhancer starr_08114 Neighboring gene glycosyltransferase 28 domain containing 2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Cell-type-specific consequences of Reelin deficiency in the mouse neocortex, hippocampus, and amygdala. Boyle MP, et al. J Comp Neurol, 2011 Aug 1. PMID 21491433
    2. Placentation defects are highly prevalent in embryonic lethal mouse mutants. Perez-Garcia V, et al. Nature, 2018 Mar 22. PMID 29539633, Free PMC Article
    3. Cracking the egg: molecular dynamics and evolutionary aspects of the transition from the fully grown oocyte to embryo. Evsikov AV, et al. Genes Dev, 2006 Oct 1. PMID 17015433, Free PMC Article
    4. Mouse screen reveals multiple new genes underlying mouse and human hearing loss. Ingham NJ, et al. PLoS Biol, 2019 Apr. PMID 30973865, Free PMC Article
    5. Genetic determinants of micronucleus formation in vivo. Adams DJ, et al. Nature, 2024 Mar. PMID 38355793, Free PMC Article

    See all (14) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (3) 
    • Targeted (2) 

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in protein localization to perinuclear region of cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in protein localization to perinuclear region of cytoplasm ISO
    Inferred from Sequence Orthology
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    FHF complex subunit HOOK-interacting protein 1A
    Names
    family with sequence similarity 160, member A1
    protein FAM160A1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_172682.3 → NP_766270.2  FHF complex subunit HOOK-interacting protein 1A

      See identical proteins and their annotated locations for NP_766270.2

      Status: VALIDATED

      Source sequence(s)
      AI481830, AK036881, DV651332, DV659303
      Consensus CDS
      CCDS17442.2
      UniProtKB/Swiss-Prot
      Q505K2, Q8BZ23
      Related
      ENSMUSP00000113235.2, ENSMUST00000118408.8
      Conserved Domains (2) summary
      pfam10257
      Location:88 → 411
      RAI16-like; Retinoic acid induced 16-like protein
      pfam11489
      Location:658 → 792
      Aim21; Altered inheritance of mitochondria protein 21

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000069.7 Reference GRCm39 C57BL/6J

      Range
      85567370..85653516 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q505K2.2 GenPept UniProtKB/Swiss-Prot:Q505K2

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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