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    Ankrd34a ankyrin repeat domain 34A [ Mus musculus (house mouse) ]

    Gene ID: 545554, updated on 27-Nov-2024

    Summary

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    Official Symbol
    Ankrd34aprovided by MGI
    Official Full Name
    ankyrin repeat domain 34Aprovided by MGI
    Primary source
    MGI:MGI:3617846
    See related
    Ensembl:ENSMUSG00000049097 AllianceGenome:MGI:3617846
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Ankrd34
    Summary
    Is expressed in cerebral cortex subventricular zone; cerebral cortex ventricular layer; and cortical plate. Orthologous to human ANKRD34A (ankyrin repeat domain 34A). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in cortex adult (RPKM 9.9), cerebellum adult (RPKM 9.5) and 9 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Ankrd34a in Genome Data Viewer
    Location:
    3 F2.1; 3 41.93 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 3 NC_000069.7 (96503599..96507442)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 3 NC_000069.6 (96595928..96600126)

    Chromosome 3 - NC_000069.7Genomic Context describing neighboring genes Neighboring gene CapStarr-seq enhancer MGSCv37_chr3:96361830-96361983 Neighboring gene predicted gene 15441 Neighboring gene STARR-seq mESC enhancer starr_08439 Neighboring gene CapStarr-seq enhancer MGSCv37_chr3:96368663-96368826 Neighboring gene thioredoxin interacting protein Neighboring gene STARR-seq mESC enhancer starr_08441 Neighboring gene STARR-positive B cell enhancer ABC_E6083 Neighboring gene polymerase (RNA) III (DNA directed) polypeptide G like Neighboring gene STARR-seq mESC enhancer starr_08442 Neighboring gene STARR-positive B cell enhancer ABC_E3451 Neighboring gene predicted gene, 52628 Neighboring gene RIKEN cDNA 6330549D23 gene Neighboring gene Lix1-like Neighboring gene STARR-positive B cell enhancer ABC_E7929 Neighboring gene RNA binding motif protein 8a

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development. Bedogni F, et al. Front Mol Neurosci, 2021. PMID 34321999, Free PMC Article
    2. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article
    3. Normalization and subtraction: two approaches to facilitate gene discovery. Bonaldo MF, et al. Genome Res, 1996 Sep. PMID 8889548
    4. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article
    5. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, et al. Nature, 2002 Dec 5. PMID 12466851

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 
    • Targeted (1) 

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    ankyrin repeat domain-containing protein 34A
    Names
    ankyrin repeat domain 34

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001024851.4 → NP_001020022.2  ankyrin repeat domain-containing protein 34A

      See identical proteins and their annotated locations for NP_001020022.2

      Status: VALIDATED

      Source sequence(s)
      AC122037
      Consensus CDS
      CCDS38556.1
      UniProtKB/TrEMBL
      B2RW11
      Related
      ENSMUSP00000102707.3, ENSMUST00000058943.8
      Conserved Domains (2) summary
      COG0666
      Location:9 → 133
      ANKYR; Ankyrin repeat [Signal transduction mechanisms]
      sd00045
      Location:8 → 35
      ANK; ANK repeat [structural motif]

    2. NM_001411495.1 → NP_001398424.1  ankyrin repeat domain-containing protein 34A

      Status: VALIDATED

      Source sequence(s)
      AC122037
      UniProtKB/TrEMBL
      B2RW11

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000069.7 Reference GRCm39 C57BL/6J

      Range
      96503599..96507442
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006501711.4 → XP_006501774.1  ankyrin repeat domain-containing protein 34A isoform X1

      See identical proteins and their annotated locations for XP_006501774.1

      UniProtKB/TrEMBL
      B2RW11
      Conserved Domains (2) summary
      COG0666
      Location:9 → 133
      ANKYR; Ankyrin repeat [Signal transduction mechanisms]
      sd00045
      Location:8 → 35
      ANK; ANK repeat [structural motif]
    Nucleotide Protein Strain
    Heading Accession and Version

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