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    Uqcc1 ubiquinol-cytochrome c reductase complex assembly factor 1 [ Mus musculus (house mouse) ]

    Gene ID: 56046, updated on 9-Dec-2024

    Summary

    Official Symbol
    Uqcc1provided by MGI
    Official Full Name
    ubiquinol-cytochrome c reductase complex assembly factor 1provided by MGI
    Primary source
    MGI:MGI:1929472
    See related
    Ensembl:ENSMUSG00000005882 AllianceGenome:MGI:1929472
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Bfzb; Bfzp; Cbp3; Uqcc; 2310079L17Rik; 2410003P15Rik; 3110038N19Rik
    Summary
    Predicted to be involved in mitochondrial respiratory chain complex III assembly. Located in cytoplasmic vesicle. Is expressed in several structures, including eye and nervous system. Orthologous to human UQCC1 (ubiquinol-cytochrome c reductase complex assembly factor 1). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Ubiquitous expression in heart adult (RPKM 12.1), cerebellum adult (RPKM 6.0) and 28 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Uqcc1 in Genome Data Viewer
    Location:
    2 H1; 2 77.26 cM
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 2 NC_000068.8 (155688806..155772230, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 2 NC_000068.7 (155846886..155930310, complement)

    Chromosome 2 - NC_000068.8Genomic Context describing neighboring genes Neighboring gene eukaryotic translation initiation factor 6 Neighboring gene family with sequence similarity 83, member C Neighboring gene predicted gene, 54125 Neighboring gene STARR-seq mESC enhancer starr_06151 Neighboring gene STARR-seq mESC enhancer starr_06152 Neighboring gene growth differentiation factor 5 Neighboring gene centrosomal protein 250 Neighboring gene predicted gene, 50621

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Interactions

    General gene information

    Gene Ontology Provided by MGI

    Component Evidence Code Pubs
    located_in cytoplasmic vesicle PubMed 
    located_in mitochondrial inner membrane  
    located_in mitochondrial inner membrane  
    located_in mitochondrion PubMed 
    is_active_in mitochondrion  

    General protein information

    Preferred Names
    ubiquinol-cytochrome c reductase complex assembly factor 1
    Names
    basic FGF repressed, zinc binding protein
    basic FGF-repressed Zic-binding protein
    ubiquinol-cytochrome c reductase complex chaperone, CBP3 homolog

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001355441.1NP_001342370.1  ubiquinol-cytochrome c reductase complex assembly factor 1 isoform b

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) differs in the 5' UTR and coding sequence compared to variant 4. The resulting isoform (b) is shorter at the N-terminus compared to isoform c. Variants 2 and 3 both encode the same isoform (b).
      Source sequence(s)
      AL845445
      UniProtKB/TrEMBL
      A6PWX7
      Conserved Domains (1) summary
      pfam03981
      Location:37172
      Ubiq_cyt_C_chap; Ubiquinol-cytochrome C chaperone
    2. NM_001355442.1NP_001342371.1  ubiquinol-cytochrome c reductase complex assembly factor 1 isoform b

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) differs in the 5' UTR and coding sequence compared to variant 4. The resulting isoform (b) is shorter at the N-terminus compared to isoform c. Variants 2 and 3 both encode the same isoform (b).
      Source sequence(s)
      AL845445
      UniProtKB/TrEMBL
      A6PWX7
      Conserved Domains (1) summary
      pfam03981
      Location:37172
      Ubiq_cyt_C_chap; Ubiquinol-cytochrome C chaperone
    3. NM_001355443.1NP_001342372.1  ubiquinol-cytochrome c reductase complex assembly factor 1 isoform c

      Status: VALIDATED

      Description
      Transcript Variant: This variant (4) represents the longest transcript and encodes the longest isoform (c).
      Source sequence(s)
      AL845445
      UniProtKB/TrEMBL
      A6PWX8
      Conserved Domains (1) summary
      pfam03981
      Location:152291
      Ubiq_cyt_C_chap; Ubiquinol-cytochrome C chaperone
    4. NM_018888.4NP_061376.2  ubiquinol-cytochrome c reductase complex assembly factor 1 isoform a

      See identical proteins and their annotated locations for NP_061376.2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) uses an alternate splice junction in the 5' end compared to variant 4. The resulting isoform (a) has a shorter and distinct N-terminus compared to isoform c.
      Source sequence(s)
      AK139488, BB761198
      Consensus CDS
      CCDS16957.2
      UniProtKB/Swiss-Prot
      A2ARK1, Q3TET9, Q9CRP2, Q9CWU6, Q9JK78
      UniProtKB/TrEMBL
      A6PWX9
      Related
      ENSMUSP00000105264.5, ENSMUST00000109636.11
      Conserved Domains (1) summary
      pfam03981
      Location:132271
      Ubiq_cyt_C_chap; Ubiquinol-cytochrome C chaperone

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000068.8 Reference GRCm39 C57BL/6J

      Range
      155688806..155772230 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_030251889.1XP_030107749.1  ubiquinol-cytochrome c reductase complex assembly factor 1 isoform X4

      Conserved Domains (1) summary
      pfam03981
      Location:132196
      Ubiq_cyt_C_chap; Ubiquinol-cytochrome C chaperone
    2. XM_011239706.3XP_011238008.1  ubiquinol-cytochrome c reductase complex assembly factor 1 isoform X3

      Conserved Domains (1) summary
      pfam03981
      Location:152216
      Ubiq_cyt_C_chap; Ubiquinol-cytochrome C chaperone
    3. XM_006499922.4XP_006499985.1  ubiquinol-cytochrome c reductase complex assembly factor 1 isoform X2

      Conserved Domains (1) summary
      pfam03981
      Location:132194
      Ubiq_cyt_C_chap; Ubiquinol-cytochrome C chaperone
    4. XM_011239705.3XP_011238007.1  ubiquinol-cytochrome c reductase complex assembly factor 1 isoform X1

      Conserved Domains (1) summary
      pfam03981
      Location:152214
      Ubiq_cyt_C_chap; Ubiquinol-cytochrome C chaperone

    RNA

    1. XR_003953679.1 RNA Sequence

      Related
      ENSMUST00000136933.8
    2. XR_003953678.1 RNA Sequence

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