Cep85l centrosomal protein 85-like [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Cep85lprovided by MGI
Official Full Name: centrosomal protein 85-likeprovided by MGI
Primary source: MGI:MGI:3642684
See related: Ensembl:ENSMUSG00000038594 AllianceGenome:MGI:3642684
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: Gm9766; 1700003O08Rik
Summary: Predicted to be involved in neuron migration. Predicted to be located in pericentriolar material. Predicted to be active in centrosome. Human ortholog(s) of this gene implicated in lissencephaly 10. Orthologous to human CEP85L (centrosomal protein 85 like). [provided by Alliance of Genome Resources, Dec 2024]
Expression: Broad expression in testis adult (RPKM 10.2), lung adult (RPKM 1.5) and 18 other tissues See more
Orthologs: human all
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Genomic context

Location:: 10 B3; 10

Exon count:: 17

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	10	NC_000076.7 (53149537..53256765, complement)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	10	NC_000076.6 (53273441..53379883, complement)

Chromosome 10 - NC_000076.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Mouse ENCODE transcriptome data
Description: RNA profiling data sets generated by the Mouse ENCODE project.
BioProject: PRJNA66167
Publication: PMID 25409824
Analysis date: n/a

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics (MGI)

Endonuclease-mediated (3)

Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables molecular_function	ND No biological Data available more info

Process	Evidence Code	Pubs
involved_in neuron migration	IEA Inferred from Electronic Annotation more info
involved_in neuron migration	ISO Inferred from Sequence Orthology more info

Component	Evidence Code	Pubs
is_active_in centrosome	IBA Inferred from Biological aspect of Ancestor more info
located_in cytoplasm	IEA Inferred from Electronic Annotation more info
located_in pericentriolar material	IEA Inferred from Electronic Annotation more info
located_in pericentriolar material	ISO Inferred from Sequence Orthology more info

General protein information

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Preferred Names: centrosomal protein of 85 kDa-like

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001204983.2 → NP_001191912.1 centrosomal protein of 85 kDa-like

See identical proteins and their annotated locations for NP_001191912.1

Status: VALIDATED

Source sequence(s)

AC105169, AC153524

Consensus CDS

CCDS56701.1

UniProtKB/Swiss-Prot

A0A1W2P884

Related

ENSMUSP00000151909.2, ENSMUST00000220443.2

Conserved Domains (1) summary

COG1196
Location:442 → 742

Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

NC_000076.7 Reference GRCm39 C57BL/6J

Range

53149537..53256765 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_006512494.5 → XP_006512557.1 centrosomal protein of 85 kDa-like isoform X2

UniProtKB/TrEMBL

E9QA61

Related

ENSMUSP00000152032.2, ENSMUST00000220376.2

Conserved Domains (1) summary

COG1196
Location:340 → 640

Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
XM_036155444.1 → XP_036011337.1 centrosomal protein of 85 kDa-like isoform X1

Conserved Domains (1) summary

COG1196
Location:430 → 730

Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
XM_017313744.3 → XP_017169233.1 centrosomal protein of 85 kDa-like isoform X2

UniProtKB/TrEMBL

E9QA61

Related

ENSMUSP00000093356.7, ENSMUST00000095691.7

Conserved Domains (1) summary

COG1196
Location:340 → 640

Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
XM_017313743.3 → XP_017169232.1 centrosomal protein of 85 kDa-like isoform X2

UniProtKB/TrEMBL

E9QA61

Conserved Domains (1) summary

COG1196
Location:340 → 640

Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]