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    ADGRE2 adhesion G protein-coupled receptor E2 [ Homo sapiens (human) ]

    Gene ID: 30817, updated on 10-Dec-2024

    Summary

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    Official Symbol
    ADGRE2provided by HGNC
    Official Full Name
    adhesion G protein-coupled receptor E2provided by HGNC
    Primary source
    HGNC:HGNC:3337
    See related
    Ensembl:ENSG00000127507 MIM:606100; AllianceGenome:HGNC:3337
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    VBU; CD97; EMR2; CD312
    Summary
    This gene encodes a member of the class B seven-span transmembrane (TM7) subfamily of G-protein coupled receptors. These proteins are characterized by an extended extracellular region with a variable number of N-terminal epidermal growth factor-like domains coupled to a TM7 domain via a mucin-like spacer domain. The encoded protein is expressed mainly in myeloid cells where it promotes cell-cell adhesion through interaction with chondroitin sulfate chains. This gene is situated in a cluster of related genes on chromosome 19. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Aug 2012]
    Expression
    Broad expression in appendix (RPKM 10.8), spleen (RPKM 6.1) and 16 other tissues See more
    Orthologs
    all
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    Genomic context

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    See ADGRE2 in Genome Data Viewer
    Location:
    19p13.12
    Exon count:
    26
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 19 NC_000019.10 (14724171..14778560, complement)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 19 NC_060943.1 (14850478..14906112, complement)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 19 NC_000019.9 (14843204..14889372, complement)

    Chromosome 19 - NC_000019.10Genomic Context describing neighboring genes Neighboring gene adhesion G protein-coupled receptor E3 Neighboring gene small nucleolar RNA, H/ACA box 104 Neighboring gene integrin subunit beta 1 pseudogene 1 Neighboring gene YPEL5 pseudogene 4 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 10262 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 10263 Neighboring gene zinc finger protein 333 Neighboring gene P300/CBP strongly-dependent group 1 enhancer GRCh37_chr19:14841378-14842577 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr19:14869525-14870048 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr19:14870049-14870574 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr19:14884311-14884812 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 14179 Neighboring gene CRISPRi-validated cis-regulatory element chr19.2424 Neighboring gene TMEM167A pseudogene 2 Neighboring gene MED14-independent group 3 enhancer GRCh37_chr19:14910875-14912074 Neighboring gene olfactory receptor family 7 subfamily C member 1 Neighboring gene olfactory receptor family 7 subfamily A member 5

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Tissue-specific circular RNA induction during human fetal development
    • Description: 35 human fetal samples from 6 tissues (3 - 7 replicates per tissue) collected between 10 and 20 weeks gestational time were sequenced using Illumina TruSeq Stranded Total RNA
    • BioProject: PRJNA270632
    • Publication: PMID 26076956
    • Analysis date: Mon Apr 2 22:54:59 2018

    Bibliography

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    Related articles in PubMed

    1. The Posttraumatic Increase of the Adhesion GPCR EMR2/ADGRE2 on Circulating Neutrophils Is Not Related to Injury Severity. Zheng L, et al. Cells, 2023 Nov 20. PMID 37998392, Free PMC Article
    2. The human EGF-TM7 family member EMR2 is a heterodimeric receptor expressed on myeloid cells. Kwakkenbos MJ, et al. J Leukoc Biol, 2002 May. PMID 11994511
    3. Detection of alternatively spliced EMR2 mRNAs in colorectal tumor cell lines but rare expression of the molecule in colorectal adenocarcinomas. Aust G, et al. Virchows Arch, 2003 Jul. PMID 12761622
    4. Proteolytic cleavage of the EMR2 receptor requires both the extracellular stalk and the GPS motif. Chang GW, et al. FEBS Lett, 2003 Jul 17. PMID 12860403
    5. Autocatalytic cleavage of the EMR2 receptor occurs at a conserved G protein-coupled receptor proteolytic site motif. Lin HH, et al. J Biol Chem, 2004 Jul 23. PMID 15150276

    See all (53) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Adhesion GPCR ADGRE2 Maintains Proteostasis to Promote Progression in Acute Myeloid Leukemia.
      Title: Adhesion GPCR ADGRE2 Maintains Proteostasis to Promote Progression in Acute Myeloid Leukemia.
    2. The Posttraumatic Increase in the Adhesion of GPCR EMR2/ADGRE2 to Circulating Neutrophils Is Not Related to Injury Severity.
      Title: The Posttraumatic Increase of the Adhesion GPCR EMR2/ADGRE2 on Circulating Neutrophils Is Not Related to Injury Severity.
    3. Stimulation of Vibratory Urticaria-Associated Adhesion-GPCR, EMR2/ADGRE2, Triggers the NLRP3 Inflammasome Activation Signal in Human Monocytes.
      Title: Stimulation of Vibratory Urticaria-Associated Adhesion-GPCR, EMR2/ADGRE2, Triggers the NLRP3 Inflammasome Activation Signal in Human Monocytes.
    4. Critical Signaling Events in the Mechanoactivation of Human Mast Cells through p.C492Y-ADGRE2.
      Title: Critical Signaling Events in the Mechanoactivation of Human Mast Cells through p.C492Y-ADGRE2.
    5. Tethered agonist exposure in intact adhesion/class B2 GPCRs through intrinsic structural flexibility of the GAIN domain.
      Title: Tethered agonist exposure in intact adhesion/class B2 GPCRs through intrinsic structural flexibility of the GAIN domain.
    6. G Protein-Coupling of Adhesion GPCRs ADGRE2/EMR2 and ADGRE5/CD97, and Activation of G Protein Signalling by an Anti-EMR2 Antibody.
      Title: G Protein-Coupling of Adhesion GPCRs ADGRE2/EMR2 and ADGRE5/CD97, and Activation of G Protein Signalling by an Anti-EMR2 Antibody.
    7. EMR2 stimulates tumor angiogenesis through RGD motif-dependent mechanism.EMR2 promotes tumor angiogenesis by overexpressing MMP-9.
      Title: The role of the RGD motif in CD97/ADGRE5-and EMR2/ADGRE2-modulated tumor angiogenesis.
    8. The ADGRE2 mutation causing familiar vibratory angioedema is not responsible for the frequent nonfamilial form.
      Title: Ordinary vibratory angioedema is not generally associated with ADGRE2 mutation.
    9. Results show that the membrane-associated EMR2-NTF displays a distinct N-glycosylation pattern. Moreover, its membrane-association ability is found to be regulated by site-specific N-glycosylation in the GAIN domain. The membrane-association of EMR2-NTF takes place in post-ER compartments and identify a unique amphipathic alpha-helix at the GAIN sub-domain A as a putative in-plane membrane anchor.
      Title: Membrane-association of EMR2/ADGRE2-NTF is regulated by site-specific N-glycosylation.
    10. miR-99a reveals two novel targets E2F2 and EMR2 that play a key role in lung tumourigenesis. By inhibiting E2F2 and EMR2, miR-99a represses in vivo the transition of epithelial cells through an EMT process concomitantly with the inhibition of stemness features and consequently decreasing the CSC population.
      Title: miR-99a reveals two novel oncogenic proteins E2F2 and EMR2 and represses stemness in lung cancer.
    Submit: New GeneRIF Correction See all GeneRIFs (25)

    Phenotypes

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    Find tests for this gene in the NIH Genetic Testing Registry (GTR)

    Review eQTL and phenotype association data in this region using PheGenI

    Associated conditions

    Description Tests
    Vibratory urticaria
    MedGen: C0157743 OMIM: 125630 GeneReviews: Not available
    		Compare labs

    Variation

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    See variants in ClinVar

    See studies and variants in dbVar

    See Variation Viewer (GRCh37.p13)

    See Variation Viewer (GRCh38)

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Clone Names

    • DKFZp781B135

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    enables G protein-coupled receptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables calcium ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables chondroitin sulfate binding IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in G protein-coupled receptor signaling pathway TAS
    Traceable Author Statement
    more info
    		 PubMed 
    involved_in adenylate cyclase-activating G protein-coupled receptor signaling pathway IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in cell adhesion IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in cell migration IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in cell surface receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in granulocyte chemotaxis IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in inflammatory response IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in regulation of mast cell degranulation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in leading edge membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in membrane TAS
    Traceable Author Statement
    more info
    		 PubMed 
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in plasma membrane TAS
    Traceable Author Statement
    more info
    		  
    located_in ruffle membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    adhesion G protein-coupled receptor E2
    Names
    CD97 antigen
    EGF-like module-containing mucin-like hormone receptor-like 2
    Leukocyte antigen CD97
    egf-like module containing, mucin-like, hormone receptor-like 2

    NCBI Reference Sequences (RefSeq)

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    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    Genomic

    1. NG_047146.1 RefSeqGene

      Range
      4982..51150
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001271052.1 → NP_001257981.1  adhesion G protein-coupled receptor E2 isoform h precursor

      Status: REVIEWED

      Description
      Transcript Variant: This variant (8) differs in the 5' UTR and lacks an alternate in-frame exon in the coding region, compared to variant 1. The encoded isoform (h) is shorter than isoform a.
      Source sequence(s)
      AC005327, AC090427, AK298700, BC127004, CN480316
      Consensus CDS
      CCDS59361.1
      UniProtKB/TrEMBL
      A0JNV7
      Related
      ENSP00000376692.3, ENST00000392965.7
      Conserved Domains (4) summary
      cd00054
      Location:119 → 154
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
      cd15439
      Location:475 → 737
      7tmB2_EMR; epidermal growth factor-like module-containing mucin-like hormone receptors, member of the class B2 family of seven-transmembrane G protein-coupled receptors
      pfam07645
      Location:212 → 243
      EGF_CA; Calcium-binding EGF domain
      pfam12662
      Location:186 → 215
      cEGF; Complement Clr-like EGF-like

    2. NM_013447.4 → NP_038475.2  adhesion G protein-coupled receptor E2 isoform a precursor

      See identical proteins and their annotated locations for NP_038475.2

      Status: REVIEWED

      Description
      Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (a).
      Source sequence(s)
      AC005327, AC090427, AK298700, BC127004, BG721006, CN480316
      Consensus CDS
      CCDS32935.1
      UniProtKB/Swiss-Prot
      B4DQ96, E7ESD7, E9PBR1, E9PEL6, E9PFQ5, E9PG91, Q8NG96, Q9UHX3, Q9Y4B1
      UniProtKB/TrEMBL
      A0JNV7
      Related
      ENSP00000319883.3, ENST00000315576.8
      Conserved Domains (4) summary
      smart00303
      Location:479 → 529
      GPS; G-protein-coupled receptor proteolytic site domain
      cd00054
      Location:119 → 154
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
      pfam07645
      Location:163 → 210
      EGF_CA; Calcium-binding EGF domain
      cl21561
      Location:533 → 774
      7tm_4; Olfactory receptor

    3. NM_152916.2 → NP_690880.1  adhesion G protein-coupled receptor E2 isoform b precursor

      Status: REVIEWED

      Source sequence(s)
      AC005327, AC090427
      Consensus CDS
      CCDS32934.1
      UniProtKB/TrEMBL
      A0JNV7
      Related
      ENSP00000470725.1, ENST00000594294.5

    4. NM_152917.2 → NP_690881.1  adhesion G protein-coupled receptor E2 isoform c precursor

      Status: REVIEWED

      Source sequence(s)
      AC005327, AC090427
      Consensus CDS
      CCDS32933.1
      UniProtKB/TrEMBL
      A0JNV7
      Related
      ENSP00000472735.1, ENST00000594076.5

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000019.10 Reference GRCh38.p14 Primary Assembly

      Range
      14724171..14778560 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_047438720.1 → XP_047294676.1  adhesion G protein-coupled receptor E2 isoform X3

      UniProtKB/TrEMBL
      A0JNV7

    2. XM_047438731.1 → XP_047294687.1  adhesion G protein-coupled receptor E2 isoform X17

      UniProtKB/TrEMBL
      Q53GP0

    3. XM_047438728.1 → XP_047294684.1  adhesion G protein-coupled receptor E2 isoform X13

      UniProtKB/TrEMBL
      Q53GP0

    4. XM_047438725.1 → XP_047294681.1  adhesion G protein-coupled receptor E2 isoform X11

      UniProtKB/TrEMBL
      A0JNV7

    5. XM_047438729.1 → XP_047294685.1  adhesion G protein-coupled receptor E2 isoform X14

      UniProtKB/TrEMBL
      Q53GP0

    6. XM_047438733.1 → XP_047294689.1  adhesion G protein-coupled receptor E2 isoform X19

      UniProtKB/TrEMBL
      A0JNV7

    7. XM_047438732.1 → XP_047294688.1  adhesion G protein-coupled receptor E2 isoform X18

      UniProtKB/TrEMBL
      Q53GP0

    8. XM_047438723.1 → XP_047294679.1  adhesion G protein-coupled receptor E2 isoform X8

      UniProtKB/TrEMBL
      Q53GP0

    9. XM_047438730.1 → XP_047294686.1  adhesion G protein-coupled receptor E2 isoform X16

      UniProtKB/TrEMBL
      A0JNV7

    10. XM_047438724.1 → XP_047294680.1  adhesion G protein-coupled receptor E2 isoform X9

      UniProtKB/TrEMBL
      Q53GP0

    11. XM_047438721.1 → XP_047294677.1  adhesion G protein-coupled receptor E2 isoform X4

      UniProtKB/TrEMBL
      Q53GP0
      Related
      ENSP00000472280.2, ENST00000596991.6

    12. XM_017026726.2 → XP_016882215.1  adhesion G protein-coupled receptor E2 isoform X5

      UniProtKB/TrEMBL
      A0JNV7

    13. XM_011527951.4 → XP_011526253.1  adhesion G protein-coupled receptor E2 isoform X6

      UniProtKB/TrEMBL
      A0JNV7
      Conserved Domains (4) summary
      smart00303
      Location:430 → 480
      GPS; G-protein-coupled receptor proteolytic site domain
      cd00054
      Location:119 → 154
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
      pfam07645
      Location:163 → 197
      EGF_CA; Calcium-binding EGF domain
      cl21561
      Location:484 → 725
      7tm_4; Olfactory receptor

    14. XM_011527949.3 → XP_011526251.1  adhesion G protein-coupled receptor E2 isoform X2

      UniProtKB/TrEMBL
      Q53GP0
      Related
      ENSP00000471297.1, ENST00000601345.5
      Conserved Domains (4) summary
      smart00303
      Location:468 → 518
      GPS; G-protein-coupled receptor proteolytic site domain
      cd00054
      Location:119 → 154
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
      pfam07645
      Location:163 → 210
      EGF_CA; Calcium-binding EGF domain
      cl21561
      Location:522 → 763
      7tm_4; Olfactory receptor

    15. XM_011527948.3 → XP_011526250.1  adhesion G protein-coupled receptor E2 isoform X1

      UniProtKB/TrEMBL
      A0JNV7
      Conserved Domains (4) summary
      smart00303
      Location:479 → 529
      GPS; G-protein-coupled receptor proteolytic site domain
      cd00054
      Location:119 → 154
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
      pfam07645
      Location:163 → 210
      EGF_CA; Calcium-binding EGF domain
      cl21561
      Location:533 → 774
      7tm_4; Olfactory receptor

    16. XM_011527953.3 → XP_011526255.1  adhesion G protein-coupled receptor E2 isoform X10

      UniProtKB/TrEMBL
      A0JNV7
      Related
      ENSP00000469277.1, ENST00000595839.5
      Conserved Domains (3) summary
      smart00303
      Location:386 → 436
      GPS; G-protein-coupled receptor proteolytic site domain
      pfam07645
      Location:119 → 153
      EGF_CA; Calcium-binding EGF domain
      cl21561
      Location:440 → 681
      7tm_4; Olfactory receptor

    17. XM_017026727.2 → XP_016882216.1  adhesion G protein-coupled receptor E2 isoform X15

      UniProtKB/TrEMBL
      Q53GP0

    18. XM_047438727.1 → XP_047294683.1  adhesion G protein-coupled receptor E2 isoform X12

      UniProtKB/TrEMBL
      A0JNV7

    19. XM_011527952.4 → XP_011526254.1  adhesion G protein-coupled receptor E2 isoform X7

      UniProtKB/TrEMBL
      A0JNV7
      Conserved Domains (3) summary
      cd00054
      Location:119 → 154
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
      pfam07645
      Location:163 → 210
      EGF_CA; Calcium-binding EGF domain
      cl21561
      Location:475 → 716
      7tm_4; Olfactory receptor

    20. XM_011527954.4 → XP_011526256.1  adhesion G protein-coupled receptor E2 isoform X20

      UniProtKB/TrEMBL
      A0JNV7
      Conserved Domains (4) summary
      smart00303
      Location:366 → 416
      GPS; G-protein-coupled receptor proteolytic site domain
      cd00054
      Location:6 → 41
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
      pfam07645
      Location:50 → 97
      EGF_CA; Calcium-binding EGF domain
      cl21561
      Location:420 → 661
      7tm_4; Olfactory receptor

    21. XM_011527955.3 → XP_011526257.1  adhesion G protein-coupled receptor E2 isoform X21

      Conserved Domains (3) summary
      smart00303
      Location:280 → 330
      GPS; G-protein-coupled receptor proteolytic site domain
      pfam07645
      Location:13 → 47
      EGF_CA; Calcium-binding EGF domain
      cl21561
      Location:334 → 575
      7tm_4; Olfactory receptor

    22. XM_047438736.1 → XP_047294692.1  adhesion G protein-coupled receptor E2 isoform X24

      UniProtKB/TrEMBL
      B4DWB8, E9PEL8
      Related
      ENSP00000376689.3, ENST00000392962.3

    23. XM_047438735.1 → XP_047294691.1  adhesion G protein-coupled receptor E2 isoform X23

    24. XM_047438734.1 → XP_047294690.1  adhesion G protein-coupled receptor E2 isoform X22

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060943.1 Alternate T2T-CHM13v2.0

      Range
      14850478..14906112 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_054320779.1 → XP_054176754.1  adhesion G protein-coupled receptor E2 isoform X26

      UniProtKB/TrEMBL
      A0JNV7

    2. XM_054320793.1 → XP_054176768.1  adhesion G protein-coupled receptor E2 isoform X17

      UniProtKB/TrEMBL
      Q53GP0

    3. XM_054320783.1 → XP_054176758.1  adhesion G protein-coupled receptor E2 isoform X28

      UniProtKB/TrEMBL
      A0JNV7

    4. XM_054320787.1 → XP_054176762.1  adhesion G protein-coupled receptor E2 isoform X29

      UniProtKB/TrEMBL
      A0JNV7

    5. XM_054320778.1 → XP_054176753.1  adhesion G protein-coupled receptor E2 isoform X25

      UniProtKB/TrEMBL
      A0JNV7

    6. XM_054320780.1 → XP_054176755.1  adhesion G protein-coupled receptor E2 isoform X27

      UniProtKB/TrEMBL
      A0JNV7

    7. XM_054320789.1 → XP_054176764.1  adhesion G protein-coupled receptor E2 isoform X13

      UniProtKB/TrEMBL
      Q53GP0

    8. XM_054320790.1 → XP_054176765.1  adhesion G protein-coupled receptor E2 isoform X14

      UniProtKB/TrEMBL
      Q53GP0

    9. XM_054320795.1 → XP_054176770.1  adhesion G protein-coupled receptor E2 isoform X19

      UniProtKB/TrEMBL
      A0JNV7

    10. XM_054320794.1 → XP_054176769.1  adhesion G protein-coupled receptor E2 isoform X18

      UniProtKB/TrEMBL
      Q53GP0

    11. XM_054320784.1 → XP_054176759.1  adhesion G protein-coupled receptor E2 isoform X8

      UniProtKB/TrEMBL
      Q53GP0

    12. XM_054320792.1 → XP_054176767.1  adhesion G protein-coupled receptor E2 isoform X16

      UniProtKB/TrEMBL
      A0JNV7

    13. XM_054320785.1 → XP_054176760.1  adhesion G protein-coupled receptor E2 isoform X9

      UniProtKB/TrEMBL
      A0JNV7

    14. XM_054320786.1 → XP_054176761.1  adhesion G protein-coupled receptor E2 isoform X10

      UniProtKB/TrEMBL
      A0JNV7

    15. XM_054320781.1 → XP_054176756.1  adhesion G protein-coupled receptor E2 isoform X5

      UniProtKB/TrEMBL
      A0JNV7

    16. XM_054320777.1 → XP_054176752.1  adhesion G protein-coupled receptor E2 isoform X2

      UniProtKB/TrEMBL
      Q53GP0

    17. XM_054320797.1 → XP_054176772.1  adhesion G protein-coupled receptor E2 isoform X21

    18. XM_054320782.1 → XP_054176757.1  adhesion G protein-coupled receptor E2 isoform X7

      UniProtKB/TrEMBL
      A0JNV7

    19. XM_054320791.1 → XP_054176766.1  adhesion G protein-coupled receptor E2 isoform X15

      UniProtKB/TrEMBL
      Q53GP0

    20. XM_054320788.1 → XP_054176763.1  adhesion G protein-coupled receptor E2 isoform X12

      UniProtKB/TrEMBL
      A0JNV7

    21. XM_054320796.1 → XP_054176771.1  adhesion G protein-coupled receptor E2 isoform X20

      UniProtKB/TrEMBL
      A0JNV7

    22. XM_054320799.1 → XP_054176774.1  adhesion G protein-coupled receptor E2 isoform X24

    23. XM_054320798.1 → XP_054176773.1  adhesion G protein-coupled receptor E2 isoform X22

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_152918.1: Suppressed sequence

      Description
      NM_152918.1: This RefSeq was permanently suppressed because currently there is insufficient support for the transcript and the protein.

    2. NM_152919.1: Suppressed sequence

      Description
      NM_152919.1: This RefSeq was permanently suppressed because currently there is insufficient support for the transcript and the protein.

    3. NM_152920.1: Suppressed sequence

      Description
      NM_152920.1: This RefSeq was permanently suppressed because currently there is insufficient support for the transcript and the protein.

    4. NM_152921.1: Suppressed sequence

      Description
      NM_152921.1: This RefSeq was permanently suppressed because currently there is insufficient support for the transcript and the protein.
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9UHX3.2 GenPept UniProtKB/Swiss-Prot:Q9UHX3

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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