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These reference sequences exist independently of genome builds. Explain
These reference sequences are curated independently of the genome
annotation cycle, so their versions may not match the RefSeq versions in the current
genome build. Identify version mismatches by comparing the version of the RefSeq in
this section to the one reported in Genomic regions,
transcripts, and products above.
mRNA and Protein(s)
-
NM_001270519.2 → NP_001257448.1 serine/threonine-protein kinase LATS1 isoform 2
See identical proteins and their annotated locations for NP_001257448.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (2) lacks the last four exons and has a 3' end that extends into an intron compared to variant 1. The resulting isoform (2) has a shorter and distinct C-terminus compared to isoform 1.
- Source sequence(s)
-
AF104413, AL358852, AL583963, BC002767
- Consensus CDS
-
CCDS59040.1
- UniProtKB/Swiss-Prot
-
O95835
- Related
- ENSP00000444678.1, ENST00000392273.7
- Conserved Domains (3) summary
-
- cd14397
Location:103 → 143
- UBA_LATS1; UBA domain found in vertebrate serine/threonine-protein kinase LATS1
- cl26247
Location:473 → 558
- DNA_pol3_delta2; DNA polymerase III, delta subunit
- cl28087
Location:467 → 673
- FtsK; DNA segregation ATPase FtsK/SpoIIIE and related proteins [Cell cycle control, cell division, chromosome partitioning]
-
NM_001350339.2 → NP_001337268.1 serine/threonine-protein kinase LATS1 isoform 3
Status: REVIEWED
- Description
- Transcript Variant: This variant (4) encodes isoform 3.
- Source sequence(s)
-
AL358852, AL583963, BX276089
- Conserved Domains (3) summary
-
- cl21453
Location:598 → 1012
- PKc_like; Protein Kinases, catalytic domain
- cl21463
Location:11 → 38
- UBA_like_SF; UBA domain-like superfamily
- cl28087
Location:343 → 491
- FtsK; DNA segregation ATPase FtsK/SpoIIIE and related proteins [Cell cycle control, cell division, chromosome partitioning]
-
NM_001350340.2 → NP_001337269.1 serine/threonine-protein kinase LATS1 isoform 4
Status: REVIEWED
- Description
- Transcript Variant: This variant (5) encodes isoform 4.
- Source sequence(s)
-
AL358852, AL583963, BX276089
- Conserved Domains (3) summary
-
- cd05625
Location:598 → 979
- STKc_LATS1; Catalytic domain of the Serine/Threonine Kinase, Large Tumor Suppressor 1
- cl21463
Location:11 → 38
- UBA_like_SF; UBA domain-like superfamily
- cl28087
Location:343 → 491
- FtsK; DNA segregation ATPase FtsK/SpoIIIE and related proteins [Cell cycle control, cell division, chromosome partitioning]
-
NM_001350392.2 → NP_001337321.1 serine/threonine-protein kinase LATS1 isoform 5
Status: REVIEWED
- Description
- Transcript Variant: This variant (6) encodes isoform 5.
- Source sequence(s)
-
AL358852, AL583963, BX276089
- UniProtKB/TrEMBL
-
Q59FN4
- Conserved Domains (2) summary
-
- cd05625
Location:423 → 804
- STKc_LATS1; Catalytic domain of the Serine/Threonine Kinase, Large Tumor Suppressor 1
- cl26464
Location:9 → 312
- Atrophin-1; Atrophin-1 family
-
NM_004690.4 → NP_004681.1 serine/threonine-protein kinase LATS1 isoform 1
See identical proteins and their annotated locations for NP_004681.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (1) encodes the longest isoform (1).
- Source sequence(s)
-
AF104413, AL358852, AW021064, BX276089
- Consensus CDS
-
CCDS34551.1
- UniProtKB/Swiss-Prot
- O95835, Q6PKD0
- Related
- ENSP00000437550.1, ENST00000543571.6
- Conserved Domains (3) summary
-
- smart00220
Location:705 → 1010
- S_TKc; Serine/Threonine protein kinases, catalytic domain
- cd14397
Location:103 → 143
- UBA_LATS1; UBA domain found in vertebrate serine/threonine-protein kinase LATS1
- cd05625
Location:703 → 1084
- STKc_LATS1; Catalytic domain of the Serine/Threonine Kinase, Large Tumor Suppressor 1
RNA
-
NR_073033.2 RNA Sequence
Status: REVIEWED
- Description
- Transcript Variant: This variant (3) uses an alternate 5' exon and contains an alternate internal exon compared to variant 1. This variant is represented as non-coding due to the presence of an upstream ORF that is predicted to interfere with translation of the longest ORF.
- Source sequence(s)
-
AK310422, AW021064, BX276089
The following sections contain reference sequences that belong to a
specific genome build. Explain
This section includes genomic Reference
Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as
RefSeqs for chromosomes and scaffolds (contigs) from both reference and alternate
assemblies. Model RNAs and proteins are also reported here.
Reference GRCh38.p14 Primary Assembly
Genomic
-
NC_000006.12 Reference GRCh38.p14 Primary Assembly
- Range
-
149658153..149718101 complement
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
XM_017011474.2 → XP_016866963.1 serine/threonine-protein kinase LATS1 isoform X1
- Conserved Domains (3) summary
-
- cd14397
Location:103 → 143
- UBA_LATS1; UBA domain found in vertebrate serine/threonine-protein kinase LATS1
- cl21453
Location:703 → 1117
- PKc_like; Protein Kinases, catalytic domain
- cl28087
Location:448 → 596
- FtsK; DNA segregation ATPase FtsK/SpoIIIE and related proteins [Cell cycle control, cell division, chromosome partitioning]
-
XM_024446583.2 → XP_024302351.1 serine/threonine-protein kinase LATS1 isoform X1
- Conserved Domains (3) summary
-
- cd14397
Location:103 → 143
- UBA_LATS1; UBA domain found in vertebrate serine/threonine-protein kinase LATS1
- cl21453
Location:703 → 1117
- PKc_like; Protein Kinases, catalytic domain
- cl28087
Location:448 → 596
- FtsK; DNA segregation ATPase FtsK/SpoIIIE and related proteins [Cell cycle control, cell division, chromosome partitioning]
-
XM_047419518.1 → XP_047275474.1 serine/threonine-protein kinase LATS1 isoform X2
- UniProtKB/Swiss-Prot
- O95835, Q6PKD0
- Related
- ENSP00000253339.5, ENST00000253339.9
-
XM_047419517.1 → XP_047275473.1 serine/threonine-protein kinase LATS1 isoform X1
-
XM_047419521.1 → XP_047275477.1 serine/threonine-protein kinase LATS1 isoform X8
-
XM_017011479.2 → XP_016866968.1 serine/threonine-protein kinase LATS1 isoform X6
- UniProtKB/TrEMBL
-
Q59FN4
-
XM_011536252.3 → XP_011534554.1 serine/threonine-protein kinase LATS1 isoform X4
- UniProtKB/TrEMBL
-
Q59FN4
- Conserved Domains (3) summary
-
- smart00220
Location:705 → 961
- S_TKc; Serine/Threonine protein kinases, catalytic domain
- cd14397
Location:103 → 143
- UBA_LATS1; UBA domain found in vertebrate serine/threonine-protein kinase LATS1
- cl21453
Location:703 → 961
- PKc_like; Protein Kinases, catalytic domain
-
XM_017011477.2 → XP_016866966.1 serine/threonine-protein kinase LATS1 isoform X3
-
XM_047419519.1 → XP_047275475.1 serine/threonine-protein kinase LATS1 isoform X5
- UniProtKB/TrEMBL
-
Q59FN4
-
XM_006715603.4 → XP_006715666.1 serine/threonine-protein kinase LATS1 isoform X7
- UniProtKB/TrEMBL
-
Q59FN4
- Conserved Domains (3) summary
-
- smart00220
Location:705 → 862
- S_TKc; Serine/Threonine protein kinases, catalytic domain
- cd14397
Location:103 → 143
- UBA_LATS1; UBA domain found in vertebrate serine/threonine-protein kinase LATS1
- cl21453
Location:703 → 863
- PKc_like; Protein Kinases, catalytic domain
-
XM_047419522.1 → XP_047275478.1 serine/threonine-protein kinase LATS1 isoform X9
- UniProtKB/TrEMBL
-
Q59FN4
RNA
-
XR_007059386.1 RNA Sequence
Alternate T2T-CHM13v2.0
Genomic
-
NC_060930.1 Alternate T2T-CHM13v2.0
- Range
-
150857942..150917878 complement
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
XM_054356744.1 → XP_054212719.1 serine/threonine-protein kinase LATS1 isoform X1
-
XM_054356745.1 → XP_054212720.1 serine/threonine-protein kinase LATS1 isoform X1
-
XM_054356747.1 → XP_054212722.1 serine/threonine-protein kinase LATS1 isoform X2
- UniProtKB/Swiss-Prot
- O95835, Q6PKD0
-
XM_054356746.1 → XP_054212721.1 serine/threonine-protein kinase LATS1 isoform X1
-
XM_054356753.1 → XP_054212728.1 serine/threonine-protein kinase LATS1 isoform X8
-
XM_054356751.1 → XP_054212726.1 serine/threonine-protein kinase LATS1 isoform X6
- UniProtKB/TrEMBL
-
Q59FN4
-
XM_054356749.1 → XP_054212724.1 serine/threonine-protein kinase LATS1 isoform X4
- UniProtKB/TrEMBL
-
Q59FN4
-
XM_054356748.1 → XP_054212723.1 serine/threonine-protein kinase LATS1 isoform X3
-
XM_054356750.1 → XP_054212725.1 serine/threonine-protein kinase LATS1 isoform X5
- UniProtKB/TrEMBL
-
Q59FN4
-
XM_054356752.1 → XP_054212727.1 serine/threonine-protein kinase LATS1 isoform X7
- UniProtKB/TrEMBL
-
Q59FN4
-
XM_054356754.1 → XP_054212729.1 serine/threonine-protein kinase LATS1 isoform X9
- UniProtKB/TrEMBL
-
Q59FN4
RNA
-
XR_008487506.1 RNA Sequence