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    MIR548M microRNA 548m [ Homo sapiens (human) ]

    Gene ID: 100313772, updated on 10-Dec-2024

    Summary

    Official Symbol
    MIR548Mprovided by HGNC
    Official Full Name
    microRNA 548mprovided by HGNC
    Primary source
    HGNC:HGNC:35331
    See related
    Ensembl:ENSG00000221187 miRBase:MI0006400; AllianceGenome:HGNC:35331
    Gene type
    ncRNA
    RefSeq status
    PROVISIONAL
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    MIRN548M
    Summary
    microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]
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    Genomic context

    See MIR548M in Genome Data Viewer
    Location:
    Xq21.33
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) X NC_000023.11 (95063141..95063226, complement)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) X NC_060947.1 (93508429..93508514, complement)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) X NC_000023.10 (94318140..94318225, complement)

    Chromosome X - NC_000023.11Genomic Context describing neighboring genes Neighboring gene cyclin B1 interacting protein 1 pseudogene 3 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chrX:94100291-94100831 Neighboring gene uncharacterized LOC107985710 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chrX:94117653-94118233 Neighboring gene H3K27ac hESC enhancer GRCh37_chrX:94142296-94142796 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chrX:94162743-94163280 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chrX:94163281-94163816 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chrX:94347448-94348142 Neighboring gene CDK7 strongly-dependent group 2 enhancer GRCh37_chrX:94544817-94546016 Neighboring gene uncharacterized LOC124905288 Neighboring gene calmodulin 1 pseudogene 1

    Genomic regions, transcripts, and products

    Bibliography

    General gene information

    Other Names

    • hsa-mir-548m

    Gene Ontology Provided by GOA

    Process Evidence Code Pubs
    involved_in miRNA-mediated post-transcriptional gene silencing IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    part_of RISC complex IEA
    Inferred from Electronic Annotation
    more info
     

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    RNA

    1. NR_031667.1 RNA Sequence

      Status: PROVISIONAL

      Source sequence(s)
      AL390966
      Related
      ENST00000408260.1

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000023.11 Reference GRCh38.p14 Primary Assembly

      Range
      95063141..95063226 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060947.1 Alternate T2T-CHM13v2.0

      Range
      93508429..93508514 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)