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    UBBP4 ubiquitin B pseudogene 4 [ Homo sapiens (human) ]

    Gene ID: 23666, updated on 22-Oct-2024

    Summary

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    Official Symbol
    UBBP4provided by HGNC
    Official Full Name
    ubiquitin B pseudogene 4provided by HGNC
    Primary source
    HGNC:HGNC:12467
    See related
    Ensembl:ENSG00000290919 AllianceGenome:HGNC:12467
    Gene type
    pseudo
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
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    Genomic context

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    See UBBP4 in Genome Data Viewer
    Location:
    17p11.2
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 17 NC_000017.11 (22090750..22205151)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 17 NC_060941.1 (22756789..22866794)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 17 NC_000017.10 (20771840..21731757)

    Chromosome 17 - NC_000017.11Genomic Context describing neighboring genes Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr17:21561832-21562394 Neighboring gene abhydrolase domain containing 15 pseudogene Neighboring gene MPRA-validated peak2767 silencer Neighboring gene ReSE screen-validated silencer GRCh37_chr17:21532008-21532206 Neighboring gene NCOR1 pseudogene 2 Neighboring gene ferritin light chain pseudogene 13 Neighboring gene long intergenic non-protein coding RNA 2002

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Bibliography

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    Related articles in PubMed

    1. UBB pseudogene 4 encodes functional ubiquitin variants. Dubois ML, et al. Nat Commun, 2020 Mar 11. PMID 32161257, Free PMC Article
    2. Human ubiquitin genes: one member of the UbB gene subfamily is a tetrameric non-processed pseudogene. Cowland JB, et al. FEBS Lett, 1988 Apr 11. PMID 2834222
    3. Localization of the human UbB polyubiquitin gene to chromosome band 17p11.1-17p12. Webb GC, et al. Am J Hum Genet, 1990 Feb. PMID 2154095, Free PMC Article
    4. PTP4A2 promotes lysophagy by dephosphorylation of VCP/p97 at Tyr805. Bai Y, et al. Autophagy, 2023 May. PMID 36300783, Free PMC Article
    5. Proteomic analysis of the cullin 4B interactome using proximity-dependent biotinylation in living cells. Zhang H, et al. Proteomics, 2017 Apr. PMID 28225217

    See all (14) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Phenotypes

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    Review eQTL and phenotype association data in this region using PheGenI

    Variation

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    See studies and variants in dbVar

    See Variation Viewer (GRCh37.p13)

    See Variation Viewer (GRCh38)

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    RNA

    1. NR_144546.2 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC138761
      Related
      ENST00000584755.3

    2. NR_176224.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      ABBA01006765, AC138761
      Related
      ENST00000648259.1

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000017.11 Reference GRCh38.p14 Primary Assembly

      Range
      22090750..22205151
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060941.1 Alternate T2T-CHM13v2.0

      Range
      22756789..22866794
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein
    Heading Accession and Version

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