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    elp3 elongator complex histone acetyltransferase subunit Elp3 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2541614, updated on 18-Sep-2024

    Summary

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    Official Symbol
    elp3
    Official Full Name
    elongator complex histone acetyltransferase subunit Elp3
    Primary source
    PomBase:SPAC29A4.20
    Locus tag
    SPOM_SPAC29A4.20
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
    Also known as
    kat9
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    Genomic context

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    See elp3 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    2
    Sequence:
    Chromosome: I; NC_003424.3 (5104252..5106339, complement)

    Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene protein mug95 Neighboring gene RSC-type complex ATPase Snf21 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Ca(2+)/Mn(2+)-transporting P-type ATPase P5 type Cta5

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003424.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The Elongator subunit Elp3 is a non-canonical tRNA acetyltransferase. Lin TY, et al. Nat Commun, 2019 Feb 7. PMID 30733442, Free PMC Article
    2. Expression profiling of S. pombe acetyltransferase mutants identifies redundant pathways of gene regulation. Nugent RL, et al. BMC Genomics, 2010 Jan 22. PMID 20096118, Free PMC Article
    3. Modification of tRNA(Lys) UUU by elongator is essential for efficient translation of stress mRNAs. Fernández-Vázquez J, et al. PLoS Genet, 2013. PMID 23874237, Free PMC Article
    4. Elp3 and Dph3 of Schizosaccharomyces pombe mediate cellular stress responses through tRNA(Lys)(UUU) modifications. Villahermosa D, et al. Sci Rep, 2017 Aug 3. PMID 28775286, Free PMC Article
    5. Translational control of cell division by Elongator. Bauer F, et al. Cell Rep, 2012 May 31. PMID 22768388, Free PMC Article

    See all (21) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables 4 iron, 4 sulfur cluster binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables tRNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables tRNA uridine(34) acetyltransferase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in regulation of cytoplasmic translational fidelity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in tRNA wobble base 5-methoxycarbonylmethyl-2-thiouridinylation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in tRNA wobble base 5-methoxycarbonylmethyl-2-thiouridinylation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in cytoplasm HDA PubMed 
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in cytosol HDA PubMed 
    part_of elongator holoenzyme complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    elongator complex histone acetyltransferase subunit Elp3

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003424.3 Reference assembly

      Range
      5104252..5106339 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001020291.3 → NP_594862.1  elongator complex histone acetyltransferase subunit Elp3 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_594862.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      O14023
      Conserved Domains (1) summary
      COG1243
      Location:14 → 544
      ELP3; Histone acetyltransferase, component of the RNA polymerase elongator complex [Transcription, Chromatin structure and dynamics]
    Nucleotide Protein
    Heading Accession and Version

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