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    rpn11 19S proteasome regulatory subunit, ubiquitin-specific protease subunit Rpn11 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2543040, updated on 14-Nov-2024

    Summary

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    Official Symbol
    rpn11
    Official Full Name
    19S proteasome regulatory subunit, ubiquitin-specific protease subunit Rpn11
    Primary source
    PomBase:SPAC31G5.13
    Locus tag
    SPOM_SPAC31G5.13
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
    Also known as
    bfr2; mts5; pad1; sks1
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    Genomic context

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    See rpn11 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    1
    Sequence:
    Chromosome: I; NC_003424.3 (3010646..3012307)

    Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene RNA polymerase III-inhibiting protein Maf1 Neighboring gene ncRNA Neighboring gene FAM32A family protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene glycine decarboxylase T subunit gcv1 Neighboring gene phosphatidylserine decarboxylase Psd3

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003424.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Dss1 associating with the proteasome functions in selective nuclear mRNA export in yeast. Mannen T, et al. Biochem Biophys Res Commun, 2008 Jan 25. PMID 18023413
    2. Multidrug resistance phenotype conferred by overexpressing bfr2+/pad1+/sks1+ or pap1+ genes and mediated by bfr1+ gene product, a structural and functional homologue of P-glycoprotein in Schizosaccharomyces pombe. Arioka M, et al. Biosci Biotechnol Biochem, 1998 Feb. PMID 9532803
    3. Localization of the 26S proteasome during mitosis and meiosis in fission yeast. Wilkinson CR, et al. EMBO J, 1998 Nov 16. PMID 9822592, Free PMC Article
    4. The Pad1+ gene encodes a subunit of the 26 S proteasome in fission yeast. Penney M, et al. J Biol Chem, 1998 Sep 11. PMID 9727008
    5. Analysis of a gene encoding Rpn10 of the fission yeast proteasome reveals that the polyubiquitin-binding site of this subunit is essential when Rpn12/Mts3 activity is compromised. Wilkinson CR, et al. J Biol Chem, 2000 May 19. PMID 10809753

    See all (38) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables metal-dependent deubiquitinase activity HDA PubMed 
    enables metal-dependent deubiquitinase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables proteasome binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in proteasome-mediated ubiquitin-dependent protein catabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in proteasome-mediated ubiquitin-dependent protein catabolic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in nuclear periphery HDA PubMed 
    NOT is_active_in nuclear periphery IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in nuclear periphery IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in nucleus HDA PubMed 
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of proteasome complex HDA PubMed 
    part_of proteasome complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of proteasome regulatory particle, lid subcomplex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of proteasome regulatory particle, lid subcomplex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    NOT is_active_in proteasome storage granule IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in proteasome storage granule IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    19S proteasome regulatory subunit, ubiquitin-specific protease subunit Rpn11

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003424.3 Reference assembly

      Range
      3010646..3012307
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001019440.3 → NP_594014.1  19S proteasome regulatory subunit, ubiquitin-specific protease subunit Rpn11 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_594014.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      P41878, Q10278
      Conserved Domains (1) summary
      cd08069
      Location:20 → 285
      MPN_RPN11_CSN5; Mov34/MPN/PAD-1 family: proteasomal regulatory protein Rpn11 and signalosome complex subunit CSN5
    Nucleotide Protein
    Heading Accession and Version

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