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    med1 mediator complex subunit Med1 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2542516, updated on 18-Sep-2024

    Summary

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    Official Symbol
    med1
    Official Full Name
    mediator complex subunit Med1
    Primary source
    PomBase:SPAC2F7.04
    Locus tag
    SPOM_SPAC2F7.04
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
    Also known as
    pmc2
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    Genomic context

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    See med1 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    3
    Sequence:
    Chromosome: I; NC_003424.3 (537910..540012)

    Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene DYRK family cell polarity protein kinase Pom1 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene translation initiation factor Tif5 Neighboring gene DNA polymerase X family Neighboring gene ncRNA Neighboring gene Clr6 histone deacetylase-associated PHD protein-2 Cph2

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003424.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Elimination of a specific histone H3K14 acetyltransferase complex bypasses the RNAi pathway to regulate pericentric heterochromatin functions. Reddy BD, et al. Genes Dev, 2011 Feb 1. PMID 21289066, Free PMC Article
    2. TOR complex 2 contributes to regulation of gene expression via inhibiting Gcn5 recruitment to subtelomeric and DNA replication stress genes. Cohen A, et al. PLoS Genet, 2022 Feb. PMID 35157728, Free PMC Article
    3. Two conserved modules of Schizosaccharomyces pombe Mediator regulate distinct cellular pathways. Linder T, et al. Nucleic Acids Res, 2008 May. PMID 18310102, Free PMC Article
    4. Purification and characterization of RNA polymerase II holoenzyme from Schizosaccharomyces pombe. Spåhr H, et al. J Biol Chem, 2000 Jan 14. PMID 10625684
    5. Posttranslational Arginylation Enzyme Arginyltransferase1 Shows Genetic Interactions With Specific Cellular Pathways in vivo. Wiley DJ, et al. Front Physiol, 2020. PMID 32435206, Free PMC Article

    See all (17) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables transcription coactivator activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in positive regulation of transcription initiation by RNA polymerase II EXP
    Inferred from Experiment
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of mediator complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in nucleus HDA PubMed 

    General protein information

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    Preferred Names
    mediator complex subunit Med1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003424.3 Reference assembly

      Range
      537910..540012
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001018375.3 → NP_592975.1  mediator complex subunit Med1 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_592975.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      Q09696
      Conserved Domains (1) summary
      pfam10744
      Location:40 → 357
      Med1; Mediator of RNA polymerase II transcription subunit 1
    Nucleotide Protein
    Heading Accession and Version

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