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    TAS2R19 taste 2 receptor member 19 [ Homo sapiens (human) ]

    Gene ID: 259294, updated on 27-Nov-2024

    Summary

    Official Symbol
    TAS2R19provided by HGNC
    Official Full Name
    taste 2 receptor member 19provided by HGNC
    Primary source
    HGNC:HGNC:19108
    See related
    Ensembl:ENSG00000212124 MIM:613961; AllianceGenome:HGNC:19108
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    T2R19; T2R23; T2R48; MSTP058; TAS2R23; TAS2R48
    Summary
    Predicted to enable G protein-coupled receptor activity and bitter taste receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and detection of chemical stimulus involved in sensory perception of bitter taste. Located in membrane. [provided by Alliance of Genome Resources, Nov 2024]
    Orthologs
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    Genomic context

    See TAS2R19 in Genome Data Viewer
    Location:
    12p13.2
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 12 NC_000012.12 (11021619..11022620, complement)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 12 NC_060936.1 (10894639..10895640, complement)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 12 NC_000012.11 (11174218..11175219, complement)

    Chromosome 12 - NC_000012.12Genomic Context describing neighboring genes Neighboring gene PRH1-PRR4 readthrough Neighboring gene proline rich protein HaeIII subfamily 1 Neighboring gene PRH1-TAS2R14 readthrough Neighboring gene taste 2 receptor member 50 Neighboring gene taste 2 receptor member 20 Neighboring gene taste 2 receptor member 31 Neighboring gene taste 2 receptor member 63 pseudogene

    Genomic regions, transcripts, and products

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General protein information

    Preferred Names
    taste receptor type 2 member 19
    Names
    taste receptor, type 2, member 19
    taste receptor, type 2, member 23
    taste receptor, type 2, member 48

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_176888.2NP_795369.1  taste receptor type 2 member 19

      See identical proteins and their annotated locations for NP_795369.1

      Status: VALIDATED

      Source sequence(s)
      BC101804
      Consensus CDS
      CCDS8640.1
      UniProtKB/Swiss-Prot
      P59542, Q3MIJ4, Q645X8
      UniProtKB/TrEMBL
      A0A0J9YWT6
      Related
      ENSP00000375091.2, ENST00000390673.2
      Conserved Domains (1) summary
      cd15027
      Location:3294
      7tm_TAS2R43-like; mammalian taste receptor 2, subtype 43, and related proteins, member of the seven-transmembrane G protein-coupled receptor superfamily

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000012.12 Reference GRCh38.p14 Primary Assembly

      Range
      11021619..11022620 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Reference GRCh38.p14 ALT_REF_LOCI_1

    Genomic

    1. NW_003571050.1 Reference GRCh38.p14 ALT_REF_LOCI_1

      Range
      220325..221326 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Reference GRCh38.p14 ALT_REF_LOCI_2

    Genomic

    1. NT_187658.1 Reference GRCh38.p14 ALT_REF_LOCI_2

      Range
      220313..221314 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060936.1 Alternate T2T-CHM13v2.0

      Range
      10894639..10895640 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)