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    HNRNPUL1 heterogeneous nuclear ribonucleoprotein U like 1 [ Homo sapiens (human) ]

    Gene ID: 11100, updated on 10-Dec-2024

    Summary

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    Official Symbol
    HNRNPUL1provided by HGNC
    Official Full Name
    heterogeneous nuclear ribonucleoprotein U like 1provided by HGNC
    Primary source
    HGNC:HGNC:17011
    See related
    Ensembl:ENSG00000105323 MIM:605800; AllianceGenome:HGNC:17011
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    E1BAP5; E1B-AP5; HNRPUL1
    Summary
    This gene encodes a nuclear RNA-binding protein of the heterogeneous nuclear ribonucleoprotein (hnRNP) family. This protein binds specifically to adenovirus early-1B-55kDa oncoprotein. It may play an important role in nucleocytoplasmic RNA transport, and its function is modulated by early-1B-55kDa in adenovirus-infected cells. [provided by RefSeq, Mar 2016]
    Expression
    Ubiquitous expression in testis (RPKM 41.5), ovary (RPKM 40.7) and 25 other tissues See more
    Orthologs
    mouse all
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    Genomic context

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    See HNRNPUL1 in Genome Data Viewer
    Location:
    19q13.2
    Exon count:
    20
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 19 NC_000019.10 (41262557..41307787)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 19 NC_060943.1 (44083416..44128645)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 19 NC_000019.9 (41768462..41813692)

    Chromosome 19 - NC_000019.10Genomic Context describing neighboring genes Neighboring gene H3K27ac hESC enhancer GRCh37_chr19:41698650-41699150 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr19:41700461-41700973 Neighboring gene cytochrome P450 family 2 subfamily S member 1 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr19:41712923-41713700 Neighboring gene ReSE screen-validated silencer GRCh37_chr19:41718918-41719078 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr19:41724269-41725093 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr19:41727344-41728281 Neighboring gene H3K27ac hESC enhancer GRCh37_chr19:41730156-41731091 Neighboring gene AXL receptor tyrosine kinase Neighboring gene tRNA-Lys (anticodon TTT) 10-1 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 14670 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 14671 Neighboring gene H3K27ac hESC enhancer GRCh37_chr19:41768709-41769248 Neighboring gene NANOG-H3K27ac hESC enhancer GRCh37_chr19:41769249-41769788 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr19:41769789-41770327 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 10653 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 10654 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 10655 Neighboring gene MPRA-validated peak3484 silencer Neighboring gene RNA, 7SL, cytoplasmic 34, pseudogene Neighboring gene Sharpr-MPRA regulatory region 15507 Neighboring gene BRD4-independent group 4 enhancer GRCh37_chr19:41806393-41807592 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 14672 Neighboring gene uncharacterized LOC105372401 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 14673 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 14674 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr19:41825837-41826574 Neighboring gene Sharpr-MPRA regulatory regions 2264 and 10656 Neighboring gene ReSE screen-validated silencer GRCh37_chr19:41828472-41828958 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr19:41829057-41829826 Neighboring gene coiled-coil domain containing 97 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr19:41830597-41831366 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr19:41831367-41832136 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 14675 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 10658 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr19:41833547-41834068 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 14676 Neighboring gene transforming growth factor beta 1 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 14677 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 10660 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 10661 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 10662 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 10663 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 10664

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. HNRNPUL1 inhibits cisplatin sensitivity of esophageal squamous cell carcinoma through regulating the formation of circMAN1A2. Li J, et al. Exp Cell Res, 2021 Dec 1. PMID 34688610
    2. E1B 55-kilodalton-associated protein: a cellular protein with RNA-binding activity implicated in nucleocytoplasmic transport of adenovirus and cellular mRNAs. Gabler S, et al. J Virol, 1998 Oct. PMID 9733834, Free PMC Article
    3. The Novel Role of hnRNP UL1 in Human Cell Nucleoli. Cichocka M, et al. Int J Biol Sci, 2022. PMID 35982897, Free PMC Article
    4. RNA-binding protein hnRNP UL1 binds κB sites to attenuate NF-κB-mediated inflammation. Ma Z, et al. J Autoimmun, 2022 May. PMID 35429914
    5. Protein arginine methylation during lytic adenovirus infection. Kzhyshkowska J, et al. Biochem J, 2004 Oct 15. PMID 15242333, Free PMC Article

    See all (242) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. The Novel Role of hnRNP UL1 in Human Cell Nucleoli.
      Title: The Novel Role of hnRNP UL1 in Human Cell Nucleoli.
    2. RNA-binding protein hnRNP UL1 binds kappaB sites to attenuate NF-kappaB-mediated inflammation.
      Title: RNA-binding protein hnRNP UL1 binds κB sites to attenuate NF-κB-mediated inflammation.
    3. HNRNPUL1 inhibits cisplatin sensitivity of esophageal squamous cell carcinoma through regulating the formation of circMAN1A2.
      Title: HNRNPUL1 inhibits cisplatin sensitivity of esophageal squamous cell carcinoma through regulating the formation of circMAN1A2.
    4. Genome-Wide Association Study for Alcohol-Related Cirrhosis Identifies Risk Loci in MARC1 and HNRNPUL1.
      Title: Genome-Wide Association Study for Alcohol-Related Cirrhosis Identifies Risk Loci in MARC1 and HNRNPUL1.
    5. we define the arginines within the RGG/RG motifs as the site of methylation by PRMT1 both in vitro and in vivo. The arginines within the human hnRNPUL1 RGG/RG motifs were substituted with lysines to generate hnRNPUL1(RK).
      Title: Arginine methylation of hnRNPUL1 regulates interaction with NBS1 and recruitment to sites of DNA damage.
    6. U7 snRNP represses histone gene transcription under cell cycle-arrested conditions. hnRNP UL1 is responsible for U7 snRNP-dependent transcriptional repression of replication-dependent histone genes.
      Title: U7 small nuclear ribonucleoprotein represses histone gene transcription in cell cycle-arrested cells.
    7. Despite the limitations, hnRPUL1 and PARP1 were downregulated in renal cell carcinoma and connected with the prognosis.
      Title: Heterogeneous nuclear ribonucleoprotein U-like 1 and Poly (ADP-ribose) polymerase 1 are downregulated in renal cell carcinoma and connected with the prognosis.
    8. hnRPUL1 as a new component related to PARP1 in DNA damage response and repair
      Title: The role of hnRPUL1 involved in DNA damage response is related to PARP1.
    9. hnRNPUL1 and -2 function downstream of MRN and CtBP-interacting protein (CtIP) to promote recruitment of the BLM helicase to DNA breaks.
      Title: Regulation of DNA-end resection by hnRNPU-like proteins promotes DNA double-strand break signaling and repair.
    10. E1B-AP5 is a novel surface molecule that is involved in the undifferentiated state of human embryonic stem cells
      Title: Identification and characterization of adenovirus early region 1B-associated protein 5 as a surface marker on undifferentiated human embryonic stem cells.
    Submit: New GeneRIF Correction See all GeneRIFs (17)

    Phenotypes

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    Find tests for this gene in the NIH Genetic Testing Registry (GTR)

    Review eQTL and phenotype association data in this region using PheGenI

    Variation

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    See variants in ClinVar

    See studies and variants in dbVar

    See Variation Viewer (GRCh37.p13)

    See Variation Viewer (GRCh38)

    HIV-1 interactions

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    Protein interactions

    Protein Gene Interaction Pubs
    integrase gag-pol Analysis of HIV-1 proviral integration sites in antiretroviral treatment patients indicates that HNRNPUL1 gene favors HIV-1 integration for expansion and persistence of infected cells, suggesting HIV-1 IN interacts with HNRNPUL1 PubMed

    Go to the HIV-1, Human Interaction Database

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Clone Names

    • FLJ12944

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    enables RNA binding HDA PubMed 
    enables RNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables enzyme binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in RNA processing TAS
    Traceable Author Statement
    more info
    		 PubMed 
    involved_in alternative mRNA splicing, via spliceosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in response to virus TAS
    Traceable Author Statement
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleoplasm IDA
    Inferred from Direct Assay
    more info
    		  
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of ribonucleoprotein complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in synapse IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    heterogeneous nuclear ribonucleoprotein U-like protein 1
    Names
    E1B 55kDa associated protein 5
    E1B-55 kDa-associated protein 5
    adenovirus early region 1B-associated protein 5

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001301016.3 → NP_001287945.1  heterogeneous nuclear ribonucleoprotein U-like protein 1 isoform e

      See identical proteins and their annotated locations for NP_001287945.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (5) differs in the 5' UTR and initiates translation at an alternate start codon, compared to variant 1. It encodes isoform e, which has a shorter and distinct N-terminus, compared to isoform a.
      Source sequence(s)
      AC011462, AC011510
      Consensus CDS
      CCDS82351.1
      UniProtKB/TrEMBL
      A8K3W4, B7Z4B8
      Related
      ENSP00000263367.3, ENST00000263367.7
      Conserved Domains (3) summary
      pfam13671
      Location:334 → 479
      AAA_33; AAA domain
      cd12884
      Location:122 → 299
      SPRY_hnRNP; SPRY domain in heterogeneous nuclear ribonucleoprotein U-like (hnRNP) protein 1
      cl17190
      Location:334 → 472
      NK; Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates ...

    2. NM_001321208.2 → NP_001308137.1  heterogeneous nuclear ribonucleoprotein U-like protein 1 isoform d

      Status: REVIEWED

      Source sequence(s)
      AC011462, AC011510
      Consensus CDS
      CCDS12577.1
      UniProtKB/TrEMBL
      A8K3W4
      Conserved Domains (3) summary
      pfam13671
      Location:323 → 468
      AAA_33; AAA domain
      cd12884
      Location:111 → 288
      SPRY_hnRNP; SPRY domain in heterogeneous nuclear ribonucleoprotein U-like (hnRNP) protein 1
      cl17190
      Location:323 → 461
      NK; Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates ...

    3. NM_001321211.2 → NP_001308140.1  heterogeneous nuclear ribonucleoprotein U-like protein 1 isoform d

      Status: REVIEWED

      Source sequence(s)
      AC011462, AC011510
      Consensus CDS
      CCDS12577.1
      UniProtKB/TrEMBL
      A8K3W4
      Related
      ENSP00000472629.1, ENST00000593587.5
      Conserved Domains (3) summary
      pfam13671
      Location:323 → 468
      AAA_33; AAA domain
      cd12884
      Location:111 → 288
      SPRY_hnRNP; SPRY domain in heterogeneous nuclear ribonucleoprotein U-like (hnRNP) protein 1
      cl17190
      Location:323 → 461
      NK; Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates ...

    4. NM_007040.6 → NP_008971.2  heterogeneous nuclear ribonucleoprotein U-like protein 1 isoform a

      See identical proteins and their annotated locations for NP_008971.2

      Status: REVIEWED

      Description
      Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (a).
      Source sequence(s)
      AC011462, AC011510
      Consensus CDS
      CCDS12576.1
      UniProtKB/Swiss-Prot
      B3KMW7, O76022, Q6ZSZ0, Q7L8P4, Q8N6Z4, Q96G37, Q9BUJ2, Q9HAL3, Q9UG75
      UniProtKB/TrEMBL
      A8K6U7
      Related
      ENSP00000375863.2, ENST00000392006.8
      Conserved Domains (4) summary
      smart00513
      Location:3 → 37
      SAP; Putative DNA-binding (bihelical) motif predicted to be involved in chromosomal organisation
      pfam13671
      Location:423 → 568
      AAA_33; AAA domain
      cd12884
      Location:211 → 388
      SPRY_hnRNP; SPRY domain in heterogeneous nuclear ribonucleoprotein U-like (hnRNP) protein 1
      cl17190
      Location:423 → 561
      NK; Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates ...

    5. NM_144732.5 → NP_653333.1  heterogeneous nuclear ribonucleoprotein U-like protein 1 isoform d

      See identical proteins and their annotated locations for NP_653333.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (4) differs in the 5' UTR and coding region compared to variant 1, resulting in an isoform (d) that maintains the reading frame but is shorter at the N-terminus compared to isoform a.
      Source sequence(s)
      AC011462, AC011510
      Consensus CDS
      CCDS12577.1
      UniProtKB/TrEMBL
      A8K3W4
      Related
      ENSP00000473132.1, ENST00000595018.5
      Conserved Domains (3) summary
      pfam13671
      Location:323 → 468
      AAA_33; AAA domain
      cd12884
      Location:111 → 288
      SPRY_hnRNP; SPRY domain in heterogeneous nuclear ribonucleoprotein U-like (hnRNP) protein 1
      cl17190
      Location:323 → 461
      NK; Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates ...

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000019.10 Reference GRCh38.p14 Primary Assembly

      Range
      41262557..41307787
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005258464.5 → XP_005258521.1  heterogeneous nuclear ribonucleoprotein U-like protein 1 isoform X4

      See identical proteins and their annotated locations for XP_005258521.1

      UniProtKB/TrEMBL
      A0A0A0MRA5, A8K3W4
      Related
      ENSP00000340857.3, ENST00000352456.7
      Conserved Domains (3) summary
      pfam13671
      Location:323 → 468
      AAA_33; AAA domain
      cd12884
      Location:111 → 288
      SPRY_hnRNP; SPRY domain in heterogeneous nuclear ribonucleoprotein U-like (hnRNP) protein 1
      cl17190
      Location:323 → 461
      NK; Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates ...

    2. XM_047438115.1 → XP_047294071.1  heterogeneous nuclear ribonucleoprotein U-like protein 1 isoform X7

      UniProtKB/TrEMBL
      M0R3F1
      Related
      ENSP00000473178.1, ENST00000599614.5

    3. XM_011526395.4 → XP_011524697.1  heterogeneous nuclear ribonucleoprotein U-like protein 1 isoform X4

      See identical proteins and their annotated locations for XP_011524697.1

      UniProtKB/TrEMBL
      A0A0A0MRA5, A8K3W4
      Conserved Domains (3) summary
      pfam13671
      Location:323 → 468
      AAA_33; AAA domain
      cd12884
      Location:111 → 288
      SPRY_hnRNP; SPRY domain in heterogeneous nuclear ribonucleoprotein U-like (hnRNP) protein 1
      cl17190
      Location:323 → 461
      NK; Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates ...

    4. XM_011526393.4 → XP_011524695.1  heterogeneous nuclear ribonucleoprotein U-like protein 1 isoform X4

      See identical proteins and their annotated locations for XP_011524695.1

      UniProtKB/TrEMBL
      A0A0A0MRA5, A8K3W4
      Conserved Domains (3) summary
      pfam13671
      Location:323 → 468
      AAA_33; AAA domain
      cd12884
      Location:111 → 288
      SPRY_hnRNP; SPRY domain in heterogeneous nuclear ribonucleoprotein U-like (hnRNP) protein 1
      cl17190
      Location:323 → 461
      NK; Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates ...

    5. XM_005258459.5 → XP_005258516.1  heterogeneous nuclear ribonucleoprotein U-like protein 1 isoform X1

      UniProtKB/TrEMBL
      A8K6U7
      Related
      ENSP00000367460.3, ENST00000378215.8
      Conserved Domains (4) summary
      smart00513
      Location:3 → 37
      SAP; Putative DNA-binding (bihelical) motif predicted to be involved in chromosomal organisation
      pfam13671
      Location:423 → 568
      AAA_33; AAA domain
      cd12884
      Location:211 → 388
      SPRY_hnRNP; SPRY domain in heterogeneous nuclear ribonucleoprotein U-like (hnRNP) protein 1
      cl17190
      Location:423 → 561
      NK; Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates ...

    6. XM_011526392.4 → XP_011524694.1  heterogeneous nuclear ribonucleoprotein U-like protein 1 isoform X2

      UniProtKB/TrEMBL
      A8K6U7
      Conserved Domains (4) summary
      smart00513
      Location:3 → 37
      SAP; Putative DNA-binding (bihelical) motif predicted to be involved in chromosomal organisation
      pfam13671
      Location:423 → 568
      AAA_33; AAA domain
      cd12884
      Location:211 → 388
      SPRY_hnRNP; SPRY domain in heterogeneous nuclear ribonucleoprotein U-like (hnRNP) protein 1
      cl17190
      Location:423 → 561
      NK; Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates ...

    7. XM_005258463.5 → XP_005258520.1  heterogeneous nuclear ribonucleoprotein U-like protein 1 isoform X4

      See identical proteins and their annotated locations for XP_005258520.1

      UniProtKB/TrEMBL
      A0A0A0MRA5, A8K3W4
      Conserved Domains (3) summary
      pfam13671
      Location:323 → 468
      AAA_33; AAA domain
      cd12884
      Location:111 → 288
      SPRY_hnRNP; SPRY domain in heterogeneous nuclear ribonucleoprotein U-like (hnRNP) protein 1
      cl17190
      Location:323 → 461
      NK; Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates ...

    8. XM_011526394.4 → XP_011524696.1  heterogeneous nuclear ribonucleoprotein U-like protein 1 isoform X4

      See identical proteins and their annotated locations for XP_011524696.1

      UniProtKB/TrEMBL
      A0A0A0MRA5, A8K3W4
      Conserved Domains (3) summary
      pfam13671
      Location:323 → 468
      AAA_33; AAA domain
      cd12884
      Location:111 → 288
      SPRY_hnRNP; SPRY domain in heterogeneous nuclear ribonucleoprotein U-like (hnRNP) protein 1
      cl17190
      Location:323 → 461
      NK; Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates ...

    9. XM_005258461.6 → XP_005258518.1  heterogeneous nuclear ribonucleoprotein U-like protein 1 isoform X3

      UniProtKB/TrEMBL
      A8K3W4
      Conserved Domains (3) summary
      pfam13671
      Location:334 → 479
      AAA_33; AAA domain
      cd12884
      Location:122 → 299
      SPRY_hnRNP; SPRY domain in heterogeneous nuclear ribonucleoprotein U-like (hnRNP) protein 1
      cl17190
      Location:334 → 472
      NK; Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates ...

    10. XM_047438114.1 → XP_047294070.1  heterogeneous nuclear ribonucleoprotein U-like protein 1 isoform X6

      UniProtKB/TrEMBL
      M0R3F1

    11. XM_005258465.6 → XP_005258522.1  heterogeneous nuclear ribonucleoprotein U-like protein 1 isoform X4

      See identical proteins and their annotated locations for XP_005258522.1

      UniProtKB/TrEMBL
      A0A0A0MRA5, A8K3W4
      Conserved Domains (3) summary
      pfam13671
      Location:323 → 468
      AAA_33; AAA domain
      cd12884
      Location:111 → 288
      SPRY_hnRNP; SPRY domain in heterogeneous nuclear ribonucleoprotein U-like (hnRNP) protein 1
      cl17190
      Location:323 → 461
      NK; Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates ...

    12. XM_047438113.1 → XP_047294069.1  heterogeneous nuclear ribonucleoprotein U-like protein 1 isoform X5

      UniProtKB/TrEMBL
      A8K3W4

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060943.1 Alternate T2T-CHM13v2.0

      Range
      44083416..44128645
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_054319662.1 → XP_054175637.1  heterogeneous nuclear ribonucleoprotein U-like protein 1 isoform X4

      UniProtKB/TrEMBL
      A0A0A0MRA5, A8K3W4

    2. XM_054319670.1 → XP_054175645.1  heterogeneous nuclear ribonucleoprotein U-like protein 1 isoform X7

      UniProtKB/TrEMBL
      M0R3F1

    3. XM_054319666.1 → XP_054175641.1  heterogeneous nuclear ribonucleoprotein U-like protein 1 isoform X4

      UniProtKB/TrEMBL
      A0A0A0MRA5, A8K3W4

    4. XM_054319665.1 → XP_054175640.1  heterogeneous nuclear ribonucleoprotein U-like protein 1 isoform X4

      UniProtKB/TrEMBL
      A0A0A0MRA5, A8K3W4

    5. XM_054319659.1 → XP_054175634.1  heterogeneous nuclear ribonucleoprotein U-like protein 1 isoform X1

      UniProtKB/TrEMBL
      A8K6U7

    6. XM_054319660.1 → XP_054175635.1  heterogeneous nuclear ribonucleoprotein U-like protein 1 isoform X2

      UniProtKB/TrEMBL
      A8K6U7

    7. XM_054319664.1 → XP_054175639.1  heterogeneous nuclear ribonucleoprotein U-like protein 1 isoform X4

      UniProtKB/TrEMBL
      A0A0A0MRA5, A8K3W4

    8. XM_054319667.1 → XP_054175642.1  heterogeneous nuclear ribonucleoprotein U-like protein 1 isoform X4

      UniProtKB/TrEMBL
      A0A0A0MRA5, A8K3W4

    9. XM_054319663.1 → XP_054175638.1  heterogeneous nuclear ribonucleoprotein U-like protein 1 isoform X4

      UniProtKB/TrEMBL
      A0A0A0MRA5, A8K3W4

    10. XM_054319668.1 → XP_054175643.1  heterogeneous nuclear ribonucleoprotein U-like protein 1 isoform X5

      UniProtKB/TrEMBL
      A8K3W4

    11. XM_054319661.1 → XP_054175636.1  heterogeneous nuclear ribonucleoprotein U-like protein 1 isoform X3

      UniProtKB/TrEMBL
      A8K3W4

    12. XM_054319669.1 → XP_054175644.1  heterogeneous nuclear ribonucleoprotein U-like protein 1 isoform X6

      UniProtKB/TrEMBL
      M0R3F1

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_144733.1: Suppressed sequence

      Description
      NM_144733.1: This RefSeq was permanently suppressed because currently there is insufficient support for the transcript and the protein.

    2. NM_144734.1: Suppressed sequence

      Description
      NM_144734.1: This RefSeq was permanently suppressed because currently there is insufficient support for the transcript and the protein.
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9BUJ2.2 GenPept UniProtKB/Swiss-Prot:Q9BUJ2

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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