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    SNORD109B small nucleolar RNA, C/D box 109B [ Homo sapiens (human) ]

    Gene ID: 338429, updated on 10-Dec-2024

    Summary

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    Official Symbol
    SNORD109Bprovided by HGNC
    Official Full Name
    small nucleolar RNA, C/D box 109Bprovided by HGNC
    Primary source
    HGNC:HGNC:32774
    See related
    Ensembl:ENSG00000239169 AllianceGenome:HGNC:32774
    Gene type
    snoRNA
    RefSeq status
    REVIEWED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    HBII-438B
    Summary
    This gene encodes a C/D box-type small nucleolar RNA that is expressed predominantly in the brain. Expression of this RNA is not detectable in the brains of patients with Prader-Willi syndrome. [provided by RefSeq, Jun 2010]
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    Genomic context

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    See SNORD109B in Genome Data Viewer
    Location:
    15q11.2
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 15 NC_000015.10 (25278343..25278409)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 15 NC_060939.1 (23015008..23015074)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 15 NC_000015.9 (25523490..25523556)

    Chromosome 15 - NC_000015.10Genomic Context describing neighboring genes Neighboring gene small nucleolar RNA host gene 14 Neighboring gene small nucleolar RNA, C/D box 115-47 Neighboring gene small nucleolar RNA, C/D box 115-48 Neighboring gene Sharpr-MPRA regulatory region 5757 Neighboring gene ubiquitin protein ligase E3A Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancers GRCh37_chr15:25683287-25684232 and GRCh37_chr15:25684233-25685178 Neighboring gene NANOG-H3K27ac hESC enhancer GRCh37_chr15:25726194-25726733 Neighboring gene Sharpr-MPRA regulatory region 718 Neighboring gene long intergenic non-protein coding RNA 2250 Neighboring gene CDK7 strongly-dependent group 2 enhancer GRCh37_chr15:25789643-25790842 Neighboring gene uncharacterized LOC107984789

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The IC-SNURF-SNRPN transcript serves as a host for multiple small nucleolar RNA species and as an antisense RNA for UBE3A. Runte M, et al. Hum Mol Genet, 2001 Nov 1. PMID 11726556
    2. Eukaryotic snoRNAs: a paradigm for gene expression flexibility. Dieci G, et al. Genomics, 2009 Aug. PMID 19446021
    3. Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing. Fei T, et al. Proc Natl Acad Sci U S A, 2017 Jun 27. PMID 28611215, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Phenotypes

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    Review eQTL and phenotype association data in this region using PheGenI

    Copy number response

    Description
    Copy number response
    Haploinsufficency

    No evidence available (Last evaluated 2012-04-28)

    ClinGen Genome Curation Page
    Triplosensitivity

    No evidence available (Last evaluated 2012-04-28)

    ClinGen Genome Curation Page

    Variation

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    See variants in ClinVar

    See studies and variants in dbVar

    See Variation Viewer (GRCh37.p13)

    See Variation Viewer (GRCh38)

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Other Names

    • HBII-438B C/D box snoRNA

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    RNA

    1. NR_001289.1 RNA Sequence

      Status: REVIEWED

      Source sequence(s)
      AC100774
      Related
      ENST00000458961.1

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000015.10 Reference GRCh38.p14 Primary Assembly

      Range
      25278343..25278409
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060939.1 Alternate T2T-CHM13v2.0

      Range
      23015008..23015074
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein
    Heading Accession and Version

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