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    VEZT vezatin, adherens junctions transmembrane protein [ Homo sapiens (human) ]

    Gene ID: 55591, updated on 10-Dec-2024

    Summary

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    Official Symbol
    VEZTprovided by HGNC
    Official Full Name
    vezatin, adherens junctions transmembrane proteinprovided by HGNC
    Primary source
    HGNC:HGNC:18258
    See related
    Ensembl:ENSG00000028203 MIM:619749; AllianceGenome:HGNC:18258
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    VEZATIN
    Summary
    This gene encodes a transmembrane protein which has been localized to adherens junctions and shown to bind to myosin VIIA. Examination of expression of this gene in gastric cancer tissues have shown that expression is decreased which appears to be related to hypermethylation of the promoter. Expression of this gene may also be inhibited by binding of a specific microRNA to a target sequence in the 3' UTR of the transcripts. A pseudogene of this gene is located on the X chromosome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2011]
    Expression
    Ubiquitous expression in thyroid (RPKM 16.2), placenta (RPKM 10.3) and 25 other tissues See more
    Orthologs
    mouse all
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    Genomic context

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    See VEZT in Genome Data Viewer
    Location:
    12q22
    Exon count:
    19
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 12 NC_000012.12 (95217807..95302799)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 12 NC_060936.1 (95198602..95283569)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 12 NC_000012.11 (95611583..95696575)

    Chromosome 12 - NC_000012.12Genomic Context describing neighboring genes Neighboring gene peroxiredoxin 6 pseudogene Neighboring gene FYVE, RhoGEF and PH domain containing 6 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr12:95508516-95509249 Neighboring gene MPRA-validated peak1898 silencer Neighboring gene ribosomal protein L14 pseudogene 4 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 4737 Neighboring gene H3K27ac hESC enhancer GRCh37_chr12:95591907-95592408 Neighboring gene H3K27ac hESC enhancer GRCh37_chr12:95592409-95592908 Neighboring gene Sharpr-MPRA regulatory region 9597 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 6807 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr12:95610907-95611501 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr12:95611502-95612097 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 6809 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr12:95629839-95630536 Neighboring gene RNA, U6 small nuclear 808, pseudogene Neighboring gene CBX3 pseudogene 5 Neighboring gene microRNA 3685 Neighboring gene microRNA 331

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Bibliography

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    Related articles in PubMed

    1. VEZT as a novel independent prognostic factor in gastric cancer. Li YS, et al. Cancer Biomark, 2015. PMID 25792470
    2. Replication and meta-analysis of previous genome-wide association studies confirm vezatin as the locus with the strongest evidence for association with endometriosis. Pagliardini L, et al. Hum Reprod, 2015 Apr. PMID 25678572
    3. Up-regulation of VEZT by small activating RNA inhibits the proliferation, invasion and migration of gastric cancer cells. Xie D, et al. Biochem Biophys Res Commun, 2017 Jan 22. PMID 27856244
    4. VEZT, a novel putative tumor suppressor, suppresses the growth and tumorigenicity of gastric cancer. Miao R, et al. PLoS One, 2013. PMID 24069310, Free PMC Article
    5. Down-regulation of VEZT gene expression in human gastric cancer involves promoter methylation and miR-43c. Guo X, et al. Biochem Biophys Res Commun, 2011 Jan 14. PMID 21156161

    See all (53) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Vezatin regulates seizures by controlling AMPAR-mediated synaptic activity.
      Title: Vezatin regulates seizures by controlling AMPAR-mediated synaptic activity.
    2. We found a genetic association between rs11031006 (FSHB) SNP and endometriosis. WNT4 and VEZT genes constitute the most consistently associated genes with endometriosis. In the present study, an association of rs7521902 (WNT4) and rs10859871 (VEZT) was confirmed in women with endometriosis at the genotypic but not the allelic level.
      Title: The role of gene polymorphisms in endometriosis.
    3. This study identified the most effective small activating RNA via real-time PCR and Western blot. The selected small activating RNA inhibited the growth, invasion and migration of gastric cancer cells by specially reactivating VEZT.
      Title: Up-regulation of VEZT by small activating RNA inhibits the proliferation, invasion and migration of gastric cancer cells.
    4. VEZT expression levels can be considered as a biomarker for gastric cancer progression, lymphatic metastasis and as a novel independent prognostic factor.
      Title: VEZT as a novel independent prognostic factor in gastric cancer.
    5. vezatin and nearby SNP rs10859871 may have a role in endometriosis [meta-analysis]
      Title: Replication and meta-analysis of previous genome-wide association studies confirm vezatin as the locus with the strongest evidence for association with endometriosis.
    6. VEZT, a novel putative tumor suppressor, suppresses the growth and tumorigenicity of gastric cancer.
      Title: VEZT, a novel putative tumor suppressor, suppresses the growth and tumorigenicity of gastric cancer.
    7. function of mouse vezatin in mouse blastocyst morphogenesis
      Title: Vezatin, a protein associated to adherens junctions, is required for mouse blastocyst morphogenesis.
    8. miR-43c directly targets adherens junctions' transmembrane protein (VEZT) and suppresses VEZT protein expression.
      Title: Down-regulation of VEZT gene expression in human gastric cancer involves promoter methylation and miR-43c.
    Submit: New GeneRIF Correction

    Phenotypes

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    Find tests for this gene in the NIH Genetic Testing Registry (GTR)

    Review eQTL and phenotype association data in this region using PheGenI

    EBI GWAS Catalog

    Description
    Genome-wide association meta-analysis identifies new endometriosis risk loci.
    EBI GWAS Catalog
    Genome-wide association study link novel loci to endometriosis.
    EBI GWAS Catalog

    Variation

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    See variants in ClinVar

    See studies and variants in dbVar

    See Variation Viewer (GRCh37.p13)

    See Variation Viewer (GRCh38)

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Clone Names

    • DKFZp761C241

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    enables myosin binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in cell-cell adhesion IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    located_in acrosomal vesicle IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in adherens junction IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in cytosol IDA
    Inferred from Direct Assay
    more info
    		  
    located_in nucleoplasm IDA
    Inferred from Direct Assay
    more info
    		  
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of stereocilia ankle link complex ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    located_in stereocilium membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    vezatin

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    Genomic

    1. NG_028987.2 RefSeqGene

      Range
      5062..90054
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001352088.2 → NP_001339017.1  vezatin isoform a

      Status: REVIEWED

      Description
      Transcript Variant: This variant (4) encodes the longest isoform (a).
      Source sequence(s)
      AC084879, AC127165
      UniProtKB/TrEMBL
      F8W8C2
      Conserved Domains (1) summary
      pfam12632
      Location:169 → 461
      Vezatin; Mysoin-binding motif of peroxisomes

    2. NM_001352089.2 → NP_001339018.1  vezatin isoform c

      Status: REVIEWED

      Source sequence(s)
      AC084879, AC127165
      UniProtKB/TrEMBL
      F8W8C2
      Conserved Domains (1) summary
      pfam12632
      Location:150 → 442
      Vezatin; Mysoin-binding motif of peroxisomes

    3. NM_001352090.2 → NP_001339019.1  vezatin isoform d

      Status: REVIEWED

      Source sequence(s)
      AC084879, AC127165
      UniProtKB/TrEMBL
      F8W8C2
      Conserved Domains (1) summary
      pfam12632
      Location:120 → 408
      Vezatin; Mysoin-binding motif of peroxisomes

    4. NM_001352091.2 → NP_001339020.1  vezatin isoform e

      Status: REVIEWED

      Source sequence(s)
      AC084879, AC127165
      UniProtKB/TrEMBL
      F8W8C2
      Conserved Domains (1) summary
      pfam12632
      Location:119 → 407
      Vezatin; Mysoin-binding motif of peroxisomes

    5. NM_001352092.2 → NP_001339021.1  vezatin isoform f

      Status: REVIEWED

      Description
      Transcript Variant: This variant (8), as well as variant 9, encodes isoform f.
      Source sequence(s)
      AC084879, AC127165
      UniProtKB/TrEMBL
      F8W8C2
      Conserved Domains (1) summary
      pfam12632
      Location:102 → 394
      Vezatin; Mysoin-binding motif of peroxisomes

    6. NM_001352093.2 → NP_001339022.1  vezatin isoform f

      Status: REVIEWED

      Description
      Transcript Variant: This variant (9), as well as variant 8, encodes isoform f.
      Source sequence(s)
      AC084879, AC127165
      UniProtKB/TrEMBL
      F8W8C2
      Related
      ENSP00000380894.4, ENST00000397792.8
      Conserved Domains (1) summary
      pfam12632
      Location:102 → 394
      Vezatin; Mysoin-binding motif of peroxisomes

    7. NM_001352094.2 → NP_001339023.1  vezatin isoform g

      Status: REVIEWED

      Description
      Transcript Variant: This variant (10), as well as variants 11 and 12, encodes isoform g.
      Source sequence(s)
      AC084879, AC127165
      UniProtKB/TrEMBL
      F8W8C2
      Conserved Domains (1) summary
      pfam12632
      Location:102 → 390
      Vezatin; Mysoin-binding motif of peroxisomes

    8. NM_001352095.2 → NP_001339024.1  vezatin isoform g

      Status: REVIEWED

      Description
      Transcript Variant: This variant (11), as well as variants 10 and 12, encodes isoform g.
      Source sequence(s)
      AC084879, AC127165
      UniProtKB/TrEMBL
      F8W8C2
      Conserved Domains (1) summary
      pfam12632
      Location:102 → 390
      Vezatin; Mysoin-binding motif of peroxisomes

    9. NM_001352096.2 → NP_001339025.1  vezatin isoform g

      Status: REVIEWED

      Description
      Transcript Variant: This variant (12), as well as variants 10 and 11, encodes isoform g.
      Source sequence(s)
      AC084879, AC127165
      UniProtKB/TrEMBL
      F8W8C2
      Conserved Domains (1) summary
      pfam12632
      Location:102 → 390
      Vezatin; Mysoin-binding motif of peroxisomes

    10. NM_001352097.2 → NP_001339026.1  vezatin isoform h

      Status: REVIEWED

      Source sequence(s)
      AC084879, AC127165
      UniProtKB/TrEMBL
      F8W8C2
      Conserved Domains (1) summary
      pfam12632
      Location:72 → 364
      Vezatin; Mysoin-binding motif of peroxisomes

    11. NM_001352098.2 → NP_001339027.1  vezatin isoform i

      Status: REVIEWED

      Source sequence(s)
      AC084879, AC127165
      UniProtKB/TrEMBL
      F8W8C2
      Conserved Domains (1) summary
      pfam12632
      Location:150 → 359
      Vezatin; Mysoin-binding motif of peroxisomes

    12. NM_001352099.2 → NP_001339028.1  vezatin isoform j

      Status: REVIEWED

      Source sequence(s)
      AC084879, AC127165
      UniProtKB/TrEMBL
      F8W8C2
      Conserved Domains (1) summary
      pfam12632
      Location:12 → 304
      Vezatin; Mysoin-binding motif of peroxisomes

    13. NM_001352100.2 → NP_001339029.1  vezatin isoform k

      Status: REVIEWED

      Source sequence(s)
      AC084879, AC127165
      Conserved Domains (1) summary
      pfam12632
      Location:169 → 457
      Vezatin; Mysoin-binding motif of peroxisomes

    14. NM_001352101.2 → NP_001339030.1  vezatin isoform l

      Status: REVIEWED

      Description
      Transcript Variant: This variant (17), as well as variant 18, encodes isoform l.
      Source sequence(s)
      AC084879, AC127165
      UniProtKB/TrEMBL
      F8W8C2
      Conserved Domains (1) summary
      pfam12632
      Location:2 → 294
      Vezatin; Mysoin-binding motif of peroxisomes

    15. NM_001352102.2 → NP_001339031.1  vezatin isoform l

      Status: REVIEWED

      Description
      Transcript Variant: This variant (18), as well as variant 17, encodes isoform l.
      Source sequence(s)
      AC084879, AC127165
      UniProtKB/TrEMBL
      F8W8C2
      Conserved Domains (1) summary
      pfam12632
      Location:2 → 294
      Vezatin; Mysoin-binding motif of peroxisomes

    16. NM_001352103.2 → NP_001339032.1  vezatin isoform m

      Status: REVIEWED

      Description
      Transcript Variant: This variant (19), as well as variants 20, 21, 22, and 23, encodes isoform m.
      Source sequence(s)
      AC084879, AC127165
      UniProtKB/TrEMBL
      F8W8C2
      Conserved Domains (1) summary
      pfam12632
      Location:2 → 290
      Vezatin; Mysoin-binding motif of peroxisomes

    17. NM_001352104.2 → NP_001339033.1  vezatin isoform m

      Status: REVIEWED

      Description
      Transcript Variant: This variant (20), as well as variants 19, 21, 22, and 23, encodes isoform m.
      Source sequence(s)
      AC084879, AC127165
      UniProtKB/TrEMBL
      F8W8C2
      Conserved Domains (1) summary
      pfam12632
      Location:2 → 290
      Vezatin; Mysoin-binding motif of peroxisomes

    18. NM_001352105.2 → NP_001339034.1  vezatin isoform m

      Status: REVIEWED

      Description
      Transcript Variant: This variant (21), as well as variants 19, 20, 22, and 23, encodes isoform m.
      Source sequence(s)
      AC084879, AC127165
      UniProtKB/TrEMBL
      F8W8C2
      Conserved Domains (1) summary
      pfam12632
      Location:2 → 290
      Vezatin; Mysoin-binding motif of peroxisomes

    19. NM_001352106.2 → NP_001339035.1  vezatin isoform m

      Status: REVIEWED

      Description
      Transcript Variant: This variant (22), as well as variants 19, 20, 21, and 23, encodes isoform m.
      Source sequence(s)
      AC084879, AC127165
      UniProtKB/TrEMBL
      F8W8C2
      Conserved Domains (1) summary
      pfam12632
      Location:2 → 290
      Vezatin; Mysoin-binding motif of peroxisomes

    20. NM_001352107.2 → NP_001339036.1  vezatin isoform m

      Status: REVIEWED

      Description
      Transcript Variant: This variant (23), as well as variants 19, 20, 21, and 22, encodes isoform m.
      Source sequence(s)
      AC084879, AC127165
      UniProtKB/TrEMBL
      F8W8C2
      Conserved Domains (1) summary
      pfam12632
      Location:2 → 290
      Vezatin; Mysoin-binding motif of peroxisomes

    21. NM_001352108.2 → NP_001339037.1  vezatin isoform n

      Status: REVIEWED

      Source sequence(s)
      AC084879, AC127165
      Conserved Domains (1) summary
      pfam12632
      Location:150 → 442
      Vezatin; Mysoin-binding motif of peroxisomes

    22. NM_001352109.2 → NP_001339038.1  vezatin isoform o

      Status: REVIEWED

      Source sequence(s)
      AC084879, AC127165
      Conserved Domains (1) summary
      pfam12632
      Location:150 → 442
      Vezatin; Mysoin-binding motif of peroxisomes

    23. NM_001352110.2 → NP_001339039.1  vezatin isoform v

      Status: REVIEWED

      Source sequence(s)
      AC084879, AC127165
      Conserved Domains (1) summary
      pfam12632
      Location:150 → 438
      Vezatin; Mysoin-binding motif of peroxisomes

    24. NM_001352111.2 → NP_001339040.1  vezatin isoform p

      Status: REVIEWED

      Source sequence(s)
      AC084879, AC127165
      Conserved Domains (1) summary
      pfam12632
      Location:150 → 438
      Vezatin; Mysoin-binding motif of peroxisomes

    25. NM_001352112.2 → NP_001339041.1  vezatin isoform q

      Status: REVIEWED

      Source sequence(s)
      AC084879, AC127165
      Conserved Domains (1) summary
      pfam12632
      Location:119 → 407
      Vezatin; Mysoin-binding motif of peroxisomes

    26. NM_001352113.2 → NP_001339042.1  vezatin isoform r

      Status: REVIEWED

      Source sequence(s)
      AC084879, AC127165
      Conserved Domains (1) summary
      pfam12632
      Location:102 → 390
      Vezatin; Mysoin-binding motif of peroxisomes

    27. NM_001352114.2 → NP_001339043.1  vezatin isoform s

      Status: REVIEWED

      Source sequence(s)
      AC084879, AC127165
      Conserved Domains (1) summary
      pfam12632
      Location:2 → 207
      Vezatin; Mysoin-binding motif of peroxisomes

    28. NM_001352115.2 → NP_001339044.1  vezatin isoform t

      Status: REVIEWED

      Description
      Transcript Variant: This variant (31), as well as variants 32 and 33, encodes isoform t.
      Source sequence(s)
      AC084879, AC127165
      Conserved Domains (1) summary
      pfam12632
      Location:2 → 294
      Vezatin; Mysoin-binding motif of peroxisomes

    29. NM_001352116.2 → NP_001339045.1  vezatin isoform t

      Status: REVIEWED

      Description
      Transcript Variant: This variant (32), as well as variants 31 and 33, encodes isoform t.
      Source sequence(s)
      AC084879, AC127165
      Conserved Domains (1) summary
      pfam12632
      Location:2 → 294
      Vezatin; Mysoin-binding motif of peroxisomes

    30. NM_001352117.2 → NP_001339046.1  vezatin isoform t

      Status: REVIEWED

      Description
      Transcript Variant: This variant (33), as well as variants 31 and 32, encodes isoform t.
      Source sequence(s)
      AC084879, AC127165
      Conserved Domains (1) summary
      pfam12632
      Location:2 → 294
      Vezatin; Mysoin-binding motif of peroxisomes

    31. NM_001352118.2 → NP_001339047.1  vezatin isoform w

      Status: REVIEWED

      Source sequence(s)
      AC084879, AC127165
      Conserved Domains (1) summary
      pfam12632
      Location:2 → 290
      Vezatin; Mysoin-binding motif of peroxisomes

    32. NM_001352119.2 → NP_001339048.1  vezatin isoform u

      Status: REVIEWED

      Source sequence(s)
      AC084879, AC127165
      Conserved Domains (1) summary
      pfam12632
      Location:2 → 290
      Vezatin; Mysoin-binding motif of peroxisomes

    33. NM_017599.4 → NP_060069.3  vezatin isoform b

      See identical proteins and their annotated locations for NP_060069.3

      Status: REVIEWED

      Description
      Transcript Variant: This variant (1) encodes isoform b.
      Source sequence(s)
      AC084879, AF225417, AK225303, AL133113, BI835735, BQ023048, DB136255
      Consensus CDS
      CCDS44954.1
      UniProtKB/Swiss-Prot
      Q6P1Q3, Q9H2F4, Q9H2U5, Q9HBM0, Q9NT70, Q9NVW0, Q9UF91
      UniProtKB/TrEMBL
      F8W8C2
      Related
      ENSP00000410083.1, ENST00000436874.6
      Conserved Domains (1) summary
      pfam12632
      Location:150 → 438
      Vezatin; Mysoin-binding motif of peroxisomes

    RNA

    1. NR_038241.2 RNA Sequence

      Status: REVIEWED

      Description
      Transcript Variant: This variant (2) lacks an alternate internal exon compared to variant 1. This variant is represented as non-coding because the use of the 5'-most supported translational start codon, as used in variant 1, renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
      Source sequence(s)
      AC084879, AC127165, AK225303, BQ023048

    2. NR_038242.2 RNA Sequence

      Status: REVIEWED

      Description
      Transcript Variant: This variant (3) uses alternate splice sites in two internal exons compared to variant 1. This variant is represented as non-coding because the use of the 5'-most supported translational start codon, as used in variant 1, renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
      Source sequence(s)
      AC084879, AC127165, BC014443, BQ023048

    3. NR_147917.2 RNA Sequence

      Status: REVIEWED

      Source sequence(s)
      AC084879, AC127165

    4. NR_147918.2 RNA Sequence

      Status: REVIEWED

      Source sequence(s)
      AC084879, AC127165

    5. NR_147919.2 RNA Sequence

      Status: REVIEWED

      Source sequence(s)
      AC084879, AC127165

    6. NR_147920.2 RNA Sequence

      Status: REVIEWED

      Source sequence(s)
      AC084879, AC127165

    7. NR_147921.2 RNA Sequence

      Status: REVIEWED

      Source sequence(s)
      AC084879, AC127165

    8. NR_147922.2 RNA Sequence

      Status: REVIEWED

      Source sequence(s)
      AC084879, AC127165

    9. NR_147923.2 RNA Sequence

      Status: REVIEWED

      Source sequence(s)
      AC084879, AC127165

    10. NR_147924.2 RNA Sequence

      Status: REVIEWED

      Source sequence(s)
      AC084879, AC127165

    11. NR_147925.2 RNA Sequence

      Status: REVIEWED

      Source sequence(s)
      AC084879, AC127165

    12. NR_147926.2 RNA Sequence

      Status: REVIEWED

      Source sequence(s)
      AC084879, AC127165

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000012.12 Reference GRCh38.p14 Primary Assembly

      Range
      95217807..95302799
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_047429108.1 → XP_047285064.1  vezatin isoform X11

      UniProtKB/TrEMBL
      F8W8C2

    2. XM_047429109.1 → XP_047285065.1  vezatin isoform X11

      UniProtKB/TrEMBL
      F8W8C2

    3. XM_006719483.5 → XP_006719546.1  vezatin isoform X11

      See identical proteins and their annotated locations for XP_006719546.1

      UniProtKB/TrEMBL
      F8W8C2
      Conserved Domains (1) summary
      pfam12632
      Location:2 → 294
      Vezatin; Mysoin-binding motif of peroxisomes

    4. XM_047429116.1 → XP_047285072.1  vezatin isoform X17

    5. XM_047429115.1 → XP_047285071.1  vezatin isoform X16

      UniProtKB/TrEMBL
      F8W8C2

    6. XM_024449043.2 → XP_024304811.1  vezatin isoform X11

      UniProtKB/TrEMBL
      F8W8C2
      Conserved Domains (1) summary
      pfam12632
      Location:2 → 294
      Vezatin; Mysoin-binding motif of peroxisomes

    7. XM_047429111.1 → XP_047285067.1  vezatin isoform X12

      UniProtKB/TrEMBL
      F8W8C2

    8. XM_047429110.1 → XP_047285066.1  vezatin isoform X11

      UniProtKB/TrEMBL
      F8W8C2

    9. XM_011538549.2 → XP_011536851.1  vezatin isoform X8

      Conserved Domains (1) summary
      pfam12632
      Location:169 → 461
      Vezatin; Mysoin-binding motif of peroxisomes

    10. XM_011538550.4 → XP_011536852.1  vezatin isoform X9

      See identical proteins and their annotated locations for XP_011536852.1

      Conserved Domains (1) summary
      pfam12632
      Location:169 → 461
      Vezatin; Mysoin-binding motif of peroxisomes

    11. XM_024449042.2 → XP_024304810.1  vezatin isoform X10

      Conserved Domains (1) summary
      pfam12632
      Location:169 → 457
      Vezatin; Mysoin-binding motif of peroxisomes

    12. XM_011538544.2 → XP_011536846.1  vezatin isoform X1

      UniProtKB/TrEMBL
      F8W8C2
      Conserved Domains (1) summary
      pfam12632
      Location:169 → 457
      Vezatin; Mysoin-binding motif of peroxisomes

    13. XM_047429112.1 → XP_047285068.1  vezatin isoform X13

    14. XM_011538545.3 → XP_011536847.1  vezatin isoform X2

      UniProtKB/TrEMBL
      F8W8C2
      Conserved Domains (1) summary
      pfam12632
      Location:139 → 431
      Vezatin; Mysoin-binding motif of peroxisomes

    15. XM_017019586.2 → XP_016875075.1  vezatin isoform X3

      UniProtKB/TrEMBL
      F8W8C2

    16. XM_011538548.4 → XP_011536850.1  vezatin isoform X6

      UniProtKB/TrEMBL
      F8W8C2
      Conserved Domains (1) summary
      pfam12632
      Location:57 → 349
      Vezatin; Mysoin-binding motif of peroxisomes

    17. XM_017019592.3 → XP_016875081.1  vezatin isoform X7

      UniProtKB/TrEMBL
      F8W8C2

    18. XM_047429107.1 → XP_047285063.1  vezatin isoform X11

      UniProtKB/TrEMBL
      F8W8C2

    19. XM_006719478.3 → XP_006719541.1  vezatin isoform X4

      UniProtKB/TrEMBL
      F8W8C2
      Conserved Domains (1) summary
      pfam12632
      Location:120 → 412
      Vezatin; Mysoin-binding motif of peroxisomes

    20. XM_047429113.1 → XP_047285069.1  vezatin isoform X14

    21. XM_047429114.1 → XP_047285070.1  vezatin isoform X15

    22. XM_047429106.1 → XP_047285062.1  vezatin isoform X5

      UniProtKB/TrEMBL
      F8W8C2

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060936.1 Alternate T2T-CHM13v2.0

      Range
      95198602..95283569
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_054372483.1 → XP_054228458.1  vezatin isoform X11

      UniProtKB/TrEMBL
      F8W8C2

    2. XM_054372484.1 → XP_054228459.1  vezatin isoform X11

      UniProtKB/TrEMBL
      F8W8C2

    3. XM_054372481.1 → XP_054228456.1  vezatin isoform X11

      UniProtKB/TrEMBL
      F8W8C2

    4. XM_054372492.1 → XP_054228467.1  vezatin isoform X17

    5. XM_054372491.1 → XP_054228466.1  vezatin isoform X16

      UniProtKB/TrEMBL
      F8W8C2

    6. XM_054372489.1 → XP_054228464.1  vezatin isoform X11

      UniProtKB/TrEMBL
      F8W8C2

    7. XM_054372486.1 → XP_054228461.1  vezatin isoform X12

      UniProtKB/TrEMBL
      F8W8C2

    8. XM_054372485.1 → XP_054228460.1  vezatin isoform X11

      UniProtKB/TrEMBL
      F8W8C2

    9. XM_054372478.1 → XP_054228453.1  vezatin isoform X8

    10. XM_054372479.1 → XP_054228454.1  vezatin isoform X9

    11. XM_054372480.1 → XP_054228455.1  vezatin isoform X10

    12. XM_054372471.1 → XP_054228446.1  vezatin isoform X1

      UniProtKB/TrEMBL
      F8W8C2

    13. XM_054372487.1 → XP_054228462.1  vezatin isoform X13

    14. XM_054372472.1 → XP_054228447.1  vezatin isoform X2

      UniProtKB/TrEMBL
      F8W8C2

    15. XM_054372473.1 → XP_054228448.1  vezatin isoform X3

      UniProtKB/TrEMBL
      F8W8C2

    16. XM_054372476.1 → XP_054228451.1  vezatin isoform X6

      UniProtKB/TrEMBL
      F8W8C2

    17. XM_054372477.1 → XP_054228452.1  vezatin isoform X7

      UniProtKB/TrEMBL
      F8W8C2

    18. XM_054372482.1 → XP_054228457.1  vezatin isoform X11

      UniProtKB/TrEMBL
      F8W8C2

    19. XM_054372474.1 → XP_054228449.1  vezatin isoform X4

      UniProtKB/TrEMBL
      F8W8C2

    20. XM_054372488.1 → XP_054228463.1  vezatin isoform X14

    21. XM_054372490.1 → XP_054228465.1  vezatin isoform X15

    22. XM_054372475.1 → XP_054228450.1  vezatin isoform X5

      UniProtKB/TrEMBL
      F8W8C2
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9HBM0.3 GenPept UniProtKB/Swiss-Prot:Q9HBM0

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