Replication interactions
Interaction |
Pubs |
Knockdown of ubiquitin protein ligase E3 component n-recognin 5 (UBR5) by siRNA inhibits HIV-1 replication in HeLa P4/R5 cells |
PubMed
|
Protein interactions
Protein |
Gene |
Interaction |
Pubs |
Vpr
|
vpr
|
The interaction of HIV-1 Vpr with the EDVP E3 ligase complex (EDD, DDB1, and VPRBP) promotes Vpr-mediated downregulation of TERT protein |
PubMed
|
|
vpr
|
The interaction of Vpr with DDB1 facilitates the formation of complexes containing Cul4A-Roc1 E3 ubiquitin ligase. The association of Vpr with DDB1-containing E3 ligase mediates the degradation of UNG2 and SMUG1 |
PubMed
|
Go to the HIV-1, Human Interaction Database