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    Dthd1 death domain containing 1 [ Mus musculus (house mouse) ]

    Gene ID: 100322896, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Dthd1provided by MGI
    Official Full Name
    death domain containing 1provided by MGI
    Primary source
    MGI:MGI:4937018
    See related
    Ensembl:ENSMUSG00000090326 AllianceGenome:MGI:4937018
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Gm17384
    Summary
    Orthologous to human DTHD1 (death domain containing 1). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Low expression observed in reference dataset See more
    Orthologs
    human all
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    Genomic context

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    See Dthd1 in Genome Data Viewer
    Location:
    5 C3.1; 5 32.04 cM
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 5 NC_000071.7 (62968999..63045661)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 5 NC_000071.6 (62811656..62888318)

    Chromosome 5 - NC_000071.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 24079 Neighboring gene ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2 Neighboring gene STARR-seq mESC enhancer starr_13171 Neighboring gene CapStarr-seq enhancer MGSCv37_chr5:63169898-63170155 Neighboring gene STARR-seq mESC enhancer starr_13172 Neighboring gene STARR-seq mESC enhancer starr_13173 Neighboring gene STARR-positive B cell enhancer ABC_E11287 Neighboring gene STARR-seq mESC enhancer starr_13174 Neighboring gene CapStarr-seq enhancer MGSCv37_chr5:63249548-63249756 Neighboring gene STARR-seq mESC enhancer starr_13175 Neighboring gene STARR-seq mESC enhancer starr_13176 Neighboring gene STARR-seq mESC enhancer starr_13177 Neighboring gene predicted gene, 30837 Neighboring gene NACHT and WD repeat domain containing 2, opposite strand Neighboring gene NACHT and WD repeat domain containing 2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. A comparison of whole-genome shotgun-derived mouse chromosome 16 and the human genome. Mural RJ, et al. Science, 2002 May 31. PMID 12040188
    2. Genetic determinants of micronucleus formation in vivo. Adams DJ, et al. Nature, 2024 Mar. PMID 38355793, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (3) 

    General gene information

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    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    death domain-containing protein 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001170705.2 → NP_001164176.2  death domain-containing protein 1

      Status: VALIDATED

      Source sequence(s)
      AC117748, AC122231
      Consensus CDS
      CCDS51507.2
      UniProtKB/TrEMBL
      A0A571BG01, E9PZX1
      Related
      ENSMUSP00000158635.2, ENSMUST00000238474.2
      Conserved Domains (1) summary
      cl14633
      Location:802 → 888
      DD; Death Domain Superfamily of protein-protein interaction domains

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000071.7 Reference GRCm39 C57BL/6J

      Range
      62968999..63045661
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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