NEW
Try the new Transcript table
These reference sequences exist independently of genome builds. Explain
These reference sequences are curated independently of the genome
annotation cycle, so their versions may not match the RefSeq versions in the current
genome build. Identify version mismatches by comparing the version of the RefSeq in
this section to the one reported in Genomic regions,
transcripts, and products above.
mRNA and Protein(s)
-
NM_001198911.2 → NP_001185840.1 rho guanine nucleotide exchange factor 2 isoform 2
Status: VALIDATED
- Description
- Transcript Variant: This variant (2) has multiple differences at its 5' end, including a different translation initiation site, compared to variant 1. Variant 2 encodes a shorter protein (isoform 2) with a different N-terminus, compared to isoform 1.
- Source sequence(s)
-
AC145168
- Consensus CDS
-
CCDS57220.1
- UniProtKB/TrEMBL
- H3BJ45, H3BJU7
- Related
- ENSMUSP00000134840.2, ENSMUST00000177498.8
- Conserved Domains (4) summary
-
- cd00029
Location:25 → 70
- C1; Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second ...
- cd00160
Location:220 → 414
- RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
- cd13393
Location:454 → 569
- PH_ARHGEF2; Rho guanine nucleotide exchange factor 2 Pleckstrin homology (PH) domain
- pfam00169
Location:457 → 555
- PH; PH domain
-
NM_001198912.2 → NP_001185841.1 rho guanine nucleotide exchange factor 2 isoform 3
See identical proteins and their annotated locations for NP_001185841.1
Status: VALIDATED
- Description
- Transcript Variant: This variant (3) has a different 5' UTR and uses a downstream in-frame translation initiation site, compared to variant 1. Variant 3 encodes a shorter protein (isoform 3), compared to isoform 1.
- Source sequence(s)
-
AC145168
- Consensus CDS
-
CCDS57222.1
- UniProtKB/TrEMBL
-
H3BJU7
- Related
- ENSMUSP00000103134.4, ENSMUST00000107510.10
- Conserved Domains (4) summary
-
- cd00029
Location:13 → 58
- C1; Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second ...
- cd00160
Location:210 → 404
- RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
- TIGR02680
Location:773 → 845
- TIGR02680; TIGR02680 family protein
- cd13393
Location:444 → 559
- PH_ARHGEF2; Rho guanine nucleotide exchange factor 2 Pleckstrin homology (PH) domain
-
NM_001198913.2 → NP_001185842.1 rho guanine nucleotide exchange factor 2 isoform 4
Status: VALIDATED
- Description
- Transcript Variant: This variant (4) has multiple differences at its 5' end and uses a downstream in-frame translation initiation site, compared to variant 1. Variant 4 encodes a shorter protein (isoform 4), compared to isoform 1.
- Source sequence(s)
-
AC145168
- Consensus CDS
-
CCDS57221.1
- UniProtKB/TrEMBL
-
H3BJU7
- Related
- ENSMUSP00000127843.3, ENSMUST00000170653.9
- Conserved Domains (4) summary
-
- cd00029
Location:13 → 58
- C1; Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second ...
- cd00160
Location:208 → 402
- RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
- TIGR02680
Location:771 → 843
- TIGR02680; TIGR02680 family protein
- cd13393
Location:442 → 557
- PH_ARHGEF2; Rho guanine nucleotide exchange factor 2 Pleckstrin homology (PH) domain
-
NM_001377126.1 → NP_001364055.1 rho guanine nucleotide exchange factor 2 isoform 5
Status: VALIDATED
- Source sequence(s)
-
AC145168
- UniProtKB/TrEMBL
-
H3BJU7
- Conserved Domains (3) summary
-
- cd00160
Location:229 → 423
- RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
- cd13393
Location:463 → 578
- PH_ARHGEF2; Rho guanine nucleotide exchange factor 2 Pleckstrin homology (PH) domain
- cd20877
Location:27 → 87
- C1_ARHGEF2; protein kinase C conserved region 1 (C1 domain) found in Rho guanine nucleotide exchange factor 2 (ARHGEF2) and similar proteins
-
NM_001428493.1 → NP_001415422.1 rho guanine nucleotide exchange factor 2 isoform 6
Status: VALIDATED
- Source sequence(s)
-
AC145168
- UniProtKB/TrEMBL
- H3BJ40, H3BJU7
-
NM_001428494.1 → NP_001415423.1 rho guanine nucleotide exchange factor 2 isoform 7
Status: VALIDATED
- Source sequence(s)
-
AC145168
- UniProtKB/TrEMBL
-
H3BKH9
-
NM_001428495.1 → NP_001415424.1 rho guanine nucleotide exchange factor 2 isoform 8
Status: VALIDATED
- Source sequence(s)
-
AC145168
- UniProtKB/TrEMBL
-
H3BJU7
-
NM_001428496.1 → NP_001415425.1 rho guanine nucleotide exchange factor 2 isoform 3
Status: VALIDATED
- Source sequence(s)
-
AC145168
- UniProtKB/TrEMBL
-
H3BJU7
-
NM_001428497.1 → NP_001415426.1 rho guanine nucleotide exchange factor 2 isoform 4
Status: VALIDATED
- Source sequence(s)
-
AC145168
- UniProtKB/TrEMBL
-
H3BJU7
-
NM_008487.4 → NP_032513.3 rho guanine nucleotide exchange factor 2 isoform 1
See identical proteins and their annotated locations for NP_032513.3
Status: VALIDATED
- Description
- Transcript Variant: This variant (1) encodes the longest isoform (1).
- Source sequence(s)
-
AC145168
- Consensus CDS
-
CCDS17481.1
- UniProtKB/Swiss-Prot
- E9QNW9, O09115, Q3TBI4, Q3TJ16, Q60875, Q8CHE1, Q923E0, Q9ESG7
- UniProtKB/TrEMBL
-
H3BKH9
- Related
- ENSMUSP00000029694.8, ENSMUST00000029694.14
- Conserved Domains (4) summary
-
- cd00029
Location:40 → 85
- C1; Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second ...
- cd00160
Location:237 → 431
- RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
- cd13393
Location:471 → 586
- PH_ARHGEF2; Rho guanine nucleotide exchange factor 2 Pleckstrin homology (PH) domain
- pfam00169
Location:474 → 572
- PH; PH domain
RNA
-
NR_190380.1 RNA Sequence
Status: VALIDATED
- Source sequence(s)
-
AC145168
The following sections contain reference sequences that belong to a
specific genome build. Explain
This section includes genomic Reference
Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as
RefSeqs for chromosomes and scaffolds (contigs) from both reference and alternate
assemblies. Model RNAs and proteins are also reported here.
Reference GRCm39 C57BL/6J
Genomic
-
NC_000069.7 Reference GRCm39 C57BL/6J
- Range
-
88500427..88556839
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
XM_011240027.4 → XP_011238329.1 rho guanine nucleotide exchange factor 2 isoform X4
- UniProtKB/TrEMBL
-
H3BJX8
- Conserved Domains (4) summary
-
- cd00029
Location:240 → 285
- C1; Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second ...
- cd00160
Location:437 → 631
- RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
- TIGR02680
Location:1000 → 1072
- TIGR02680; TIGR02680 family protein
- cd13393
Location:671 → 786
- PH_ARHGEF2; Rho guanine nucleotide exchange factor 2 Pleckstrin homology (PH) domain
-
XM_006501058.4 → XP_006501121.1 rho guanine nucleotide exchange factor 2 isoform X1
- UniProtKB/TrEMBL
-
H3BJX8
- Related
- ENSMUSP00000135168.3, ENSMUST00000175903.9
- Conserved Domains (4) summary
-
- cd00029
Location:240 → 285
- C1; Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second ...
- cd00160
Location:437 → 631
- RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
- TIGR02680
Location:1000 → 1072
- TIGR02680; TIGR02680 family protein
- cd13393
Location:671 → 786
- PH_ARHGEF2; Rho guanine nucleotide exchange factor 2 Pleckstrin homology (PH) domain
-
XM_006501059.4 → XP_006501122.1 rho guanine nucleotide exchange factor 2 isoform X2
- UniProtKB/TrEMBL
-
H3BJX8
- Conserved Domains (4) summary
-
- cd00029
Location:240 → 285
- C1; Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second ...
- cd00160
Location:435 → 629
- RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
- TIGR02680
Location:998 → 1070
- TIGR02680; TIGR02680 family protein
- cd13393
Location:669 → 784
- PH_ARHGEF2; Rho guanine nucleotide exchange factor 2 Pleckstrin homology (PH) domain
-
XM_006501060.4 → XP_006501123.1 rho guanine nucleotide exchange factor 2 isoform X3
- UniProtKB/TrEMBL
-
H3BJX8
- Conserved Domains (4) summary
-
- cd00029
Location:173 → 218
- C1; Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second ...
- cd00160
Location:370 → 564
- RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
- TIGR02680
Location:933 → 1005
- TIGR02680; TIGR02680 family protein
- cd13393
Location:604 → 719
- PH_ARHGEF2; Rho guanine nucleotide exchange factor 2 Pleckstrin homology (PH) domain
-
XM_006501066.2 → XP_006501129.1 rho guanine nucleotide exchange factor 2 isoform X8
- Related
- ENSMUSP00000134834.2, ENSMUST00000176500.8
- Conserved Domains (4) summary
-
- cd00029
Location:25 → 70
- C1; Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second ...
- cd00160
Location:222 → 416
- RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
- TIGR02680
Location:785 → 857
- TIGR02680; TIGR02680 family protein
- cd13393
Location:456 → 571
- PH_ARHGEF2; Rho guanine nucleotide exchange factor 2 Pleckstrin homology (PH) domain
-
XM_030252438.2 → XP_030108298.1 rho guanine nucleotide exchange factor 2 isoform X6
- Conserved Domains (4) summary
-
- cd00029
Location:40 → 85
- C1; Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second ...
- cd00160
Location:235 → 429
- RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
- TIGR02680
Location:798 → 870
- TIGR02680; TIGR02680 family protein
- cd13393
Location:469 → 584
- PH_ARHGEF2; Rho guanine nucleotide exchange factor 2 Pleckstrin homology (PH) domain
-
XM_006501067.5 → XP_006501130.1 rho guanine nucleotide exchange factor 2 isoform X9
- Conserved Domains (4) summary
-
- cd00029
Location:13 → 58
- C1; Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second ...
- cd00160
Location:210 → 404
- RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
- TIGR02680
Location:773 → 845
- TIGR02680; TIGR02680 family protein
- cd13393
Location:444 → 559
- PH_ARHGEF2; Rho guanine nucleotide exchange factor 2 Pleckstrin homology (PH) domain
-
XM_030252439.2 → XP_030108299.1 rho guanine nucleotide exchange factor 2 isoform X10
- Conserved Domains (4) summary
-
- cd00029
Location:13 → 58
- C1; Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second ...
- cd00160
Location:208 → 402
- RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
- TIGR02680
Location:771 → 843
- TIGR02680; TIGR02680 family protein
- cd13393
Location:442 → 557
- PH_ARHGEF2; Rho guanine nucleotide exchange factor 2 Pleckstrin homology (PH) domain
-
XM_036162907.1 → XP_036018800.1 rho guanine nucleotide exchange factor 2 isoform X5
- UniProtKB/TrEMBL
-
H3BJU7
- Conserved Domains (3) summary
-
- cd00160
Location:239 → 433
- RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
- cd13393
Location:473 → 588
- PH_ARHGEF2; Rho guanine nucleotide exchange factor 2 Pleckstrin homology (PH) domain
- cd20877
Location:37 → 97
- C1_ARHGEF2; protein kinase C conserved region 1 (C1 domain) found in Rho guanine nucleotide exchange factor 2 (ARHGEF2) and similar proteins
-
XM_036162908.1 → XP_036018801.1 rho guanine nucleotide exchange factor 2 isoform X11
- Conserved Domains (2) summary
-
- cd00160
Location:58 → 252
- RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
- cd13393
Location:292 → 407
- PH_ARHGEF2; Rho guanine nucleotide exchange factor 2 Pleckstrin homology (PH) domain
-
XM_006501065.4 → XP_006501128.1 rho guanine nucleotide exchange factor 2 isoform X7
- Conserved Domains (4) summary
-
- cd00029
Location:32 → 77
- C1; Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second ...
- cd00160
Location:227 → 421
- RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
- TIGR02680
Location:790 → 862
- TIGR02680; TIGR02680 family protein
- cd13393
Location:461 → 576
- PH_ARHGEF2; Rho guanine nucleotide exchange factor 2 Pleckstrin homology (PH) domain
-
XM_036162909.1 → XP_036018802.1 rho guanine nucleotide exchange factor 2 isoform X11
- UniProtKB/TrEMBL
-
H3BJU7
- Conserved Domains (2) summary
-
- cd00160
Location:58 → 252
- RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
- cd13393
Location:292 → 407
- PH_ARHGEF2; Rho guanine nucleotide exchange factor 2 Pleckstrin homology (PH) domain