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    Ccdc157 coiled-coil domain containing 157 [ Mus musculus (house mouse) ]

    Gene ID: 216516, updated on 9-Dec-2024

    Summary

    Official Symbol
    Ccdc157provided by MGI
    Official Full Name
    coiled-coil domain containing 157provided by MGI
    Primary source
    MGI:MGI:3041210
    See related
    Ensembl:ENSMUSG00000051427 AllianceGenome:MGI:3041210
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    mKIAA1656; 4930562D19Rik
    Summary
    Used to study oligoasthenoteratozoospermia. Orthologous to human CCDC157 (coiled-coil domain containing 157). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Ubiquitous expression in testis adult (RPKM 13.6), ovary adult (RPKM 8.8) and 25 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See Ccdc157 in Genome Data Viewer
    Location:
    11 A1; 11 2.9 cM
    Exon count:
    14
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (4091123..4110999, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (4141123..4160293, complement)

    Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene transformer 2 beta homolog pseudogene Neighboring gene ring finger protein 215 Neighboring gene microRNA 3060 Neighboring gene splicing factor 3a, subunit 1 Neighboring gene STARR-positive B cell enhancer ABC_E727 Neighboring gene TBC1 domain family, member 10a Neighboring gene STARR-positive B cell enhancer ABC_E2978 Neighboring gene cytosolic arginine sensor for mTORC1 subunit 1 Neighboring gene predicted gene 11956

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    General gene information

    Markers

    Clone Names

    • KIAA1656

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
     
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
     
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
     

    General protein information

    Preferred Names
    coiled-coil domain-containing protein 157

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001164620.1NP_001158092.1  coiled-coil domain-containing protein 157 isoform 1

      See identical proteins and their annotated locations for NP_001158092.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) encodes the longer isoform (1)
      Source sequence(s)
      AK133165, AL807825
      Consensus CDS
      CCDS48743.1
      UniProtKB/Swiss-Prot
      Q0P531, Q3V0G5, Q5DTW1, Q5SPX1, Q8C5Y5
      Related
      ENSMUSP00000091074.5, ENSMUST00000093381.11
      Conserved Domains (2) summary
      COG1196
      Location:281541
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      cl28929
      Location:520681
      VirB10_like; VirB10 and similar proteins form part of core complex in Type IV secretion system (T4SS)
    2. NM_177616.3NP_808284.2  coiled-coil domain-containing protein 157 isoform 2

      See identical proteins and their annotated locations for NP_808284.2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) has an alternate exon in the 5' coding region and uses a downstream start codon, compared to variant 1. Isoform 2 has a shorter N-terminus, compared to isoform 1.
      Source sequence(s)
      AK133165, AK220409, AL807825
      Consensus CDS
      CCDS24379.1
      UniProtKB/Swiss-Prot
      Q5SPX1
      Related
      ENSMUSP00000099148.3, ENSMUST00000101626.9
      Conserved Domains (2) summary
      COG1196
      Location:179439
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      cl28929
      Location:418579
      VirB10_like; VirB10 and similar proteins form part of core complex in Type IV secretion system (T4SS)

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000077.7 Reference GRCm39 C57BL/6J

      Range
      4091123..4110999 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_036156515.1XP_036012408.1  coiled-coil domain-containing protein 157 isoform X6

      Conserved Domains (2) summary
      COG1196
      Location:179439
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      cl28929
      Location:418579
      VirB10_like; VirB10 and similar proteins form part of core complex in Type IV secretion system (T4SS)
    2. XM_036156516.1XP_036012409.1  coiled-coil domain-containing protein 157 isoform X7

      Related
      ENSMUST00000137060.2
      Conserved Domains (2) summary
      COG1196
      Location:7219
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      cl28929
      Location:140301
      VirB10_like; VirB10 and similar proteins form part of core complex in Type IV secretion system (T4SS)
    3. XM_011243677.4XP_011241979.1  coiled-coil domain-containing protein 157 isoform X5

      See identical proteins and their annotated locations for XP_011241979.1

      Conserved Domains (2) summary
      PRK13729
      Location:418521
      PRK13729; conjugal transfer pilus assembly protein TraB; Provisional
      COG1196
      Location:178456
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    4. XM_036156514.1XP_036012407.1  coiled-coil domain-containing protein 157 isoform X4

      UniProtKB/Swiss-Prot
      Q0P531, Q3V0G5, Q5DTW1, Q5SPX1, Q8C5Y5
      Conserved Domains (2) summary
      COG1196
      Location:281541
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      cl28929
      Location:520681
      VirB10_like; VirB10 and similar proteins form part of core complex in Type IV secretion system (T4SS)
    5. XM_011243675.4XP_011241977.1  coiled-coil domain-containing protein 157 isoform X2

      Conserved Domains (2) summary
      COG1196
      Location:280558
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      cl28929
      Location:520623
      VirB10_like; VirB10 and similar proteins form part of core complex in Type IV secretion system (T4SS)
    6. XM_011243673.4XP_011241975.1  coiled-coil domain-containing protein 157 isoform X1

      See identical proteins and their annotated locations for XP_011241975.1

      Conserved Domains (2) summary
      PRK13729
      Location:531634
      PRK13729; conjugal transfer pilus assembly protein TraB; Provisional
      COG1196
      Location:291569
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    7. XM_006514618.5XP_006514681.1  coiled-coil domain-containing protein 157 isoform X3

      Conserved Domains (2) summary
      PRK13729
      Location:531692
      PRK13729; conjugal transfer pilus assembly protein TraB; Provisional
      COG1196
      Location:292552
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    8. XM_030245781.2XP_030101641.1  coiled-coil domain-containing protein 157 isoform X5

      Conserved Domains (2) summary
      PRK13729
      Location:418521
      PRK13729; conjugal transfer pilus assembly protein TraB; Provisional
      COG1196
      Location:178456
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    9. XM_036156513.1XP_036012406.1  coiled-coil domain-containing protein 157 isoform X2

      Conserved Domains (2) summary
      COG1196
      Location:280558
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      cl28929
      Location:520623
      VirB10_like; VirB10 and similar proteins form part of core complex in Type IV secretion system (T4SS)
    10. XM_011243674.4XP_011241976.1  coiled-coil domain-containing protein 157 isoform X1

      See identical proteins and their annotated locations for XP_011241976.1

      Conserved Domains (2) summary
      PRK13729
      Location:531634
      PRK13729; conjugal transfer pilus assembly protein TraB; Provisional
      COG1196
      Location:291569
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]