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    Actrt3 actin related protein T3 [ Mus musculus (house mouse) ]

    Gene ID: 76652, updated on 27-Nov-2024

    Summary

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    Official Symbol
    Actrt3provided by MGI
    Official Full Name
    actin related protein T3provided by MGI
    Primary source
    MGI:MGI:1923902
    See related
    Ensembl:ENSMUSG00000037737 AllianceGenome:MGI:1923902
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Arpm1; ARP-T3; 1700119I24Rik
    Summary
    Located in male germ cell nucleus. Is expressed in several structures, including brain; genitourinary system; submandibular gland; and trachea. Orthologous to human ACTRT3 (actin related protein T3). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Restricted expression toward testis adult (RPKM 19.8) See more
    Orthologs
    human all
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    Genomic context

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    See Actrt3 in Genome Data Viewer
    Location:
    3 A3; 3 14.27 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 3 NC_000069.7 (30651221..30654021, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 3 NC_000069.6 (30597073..30599870, complement)

    Chromosome 3 - NC_000069.7Genomic Context describing neighboring genes Neighboring gene MDS1 and EVI1 complex locus Neighboring gene MDS1 and EVI1 complex locus, opposite strand Neighboring gene STARR-seq mESC enhancer starr_07290 Neighboring gene predicted gene 10258 Neighboring gene STARR-seq mESC enhancer starr_07292 Neighboring gene STARR-seq mESC enhancer starr_07293 Neighboring gene STARR-seq mESC enhancer starr_07294 Neighboring gene STARR-positive B cell enhancer ABC_E2661 Neighboring gene CapStarr-seq enhancer MGSCv37_chr3:30500978-30501161 Neighboring gene nuclear encoded tRNA valine 8 (anticodon AAC) Neighboring gene myoneurin

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Nuclear localization of profilin III-ArpM1 complex in mouse spermiogenesis. Hara Y, et al. FEBS Lett, 2008 Sep 3. PMID 18692047
    2. Molecular evolution of the actin family. Goodson HV, et al. J Cell Sci, 2002 Jul 1. PMID 12077353
    3. The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data. Koscielny G, et al. Nucleic Acids Res, 2014 Jan. PMID 24194600, Free PMC Article
    4. Genetic determinants of micronucleus formation in vivo. Adams DJ, et al. Nature, 2024 Mar. PMID 38355793, Free PMC Article
    5. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073

    See all (13) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (3) 
    • Targeted (2) 

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC130225

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in actin cytoskeleton IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in male germ cell nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    actin-related protein T3
    Names
    actin related protein M1
    actin-related protein M1 homolog

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_029690.3 → NP_083966.1  actin-related protein T3

      See identical proteins and their annotated locations for NP_083966.1

      Status: VALIDATED

      Source sequence(s)
      AC119995
      Consensus CDS
      CCDS17283.1
      UniProtKB/Swiss-Prot
      Q3KNH6, Q8BXF8, Q9D9A6
      Related
      ENSMUSP00000048360.7, ENSMUST00000047630.7
      Conserved Domains (2) summary
      smart00268
      Location:5 → 369
      ACTIN; Actin
      cl17037
      Location:9 → 369
      NBD_sugar-kinase_HSP70_actin; Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000069.7 Reference GRCm39 C57BL/6J

      Range
      30651221..30654021 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8BXF8.1 GenPept UniProtKB/Swiss-Prot:Q8BXF8

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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