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    Swt1 SWT1 RNA endoribonuclease homolog (S. cerevisiae) [ Mus musculus (house mouse) ]

    Gene ID: 66875, updated on 27-Nov-2024

    Summary

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    Official Symbol
    Swt1provided by MGI
    Official Full Name
    SWT1 RNA endoribonuclease homolog (S. cerevisiae)provided by MGI
    Primary source
    MGI:MGI:1914125
    See related
    Ensembl:ENSMUSG00000052748 AllianceGenome:MGI:1914125
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    C1orf26; 1200016B10Rik
    Summary
    Predicted to be active in nucleus. Is expressed in pancreas epithelium. Orthologous to human SWT1 (SWT1 RNA endoribonuclease homolog). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Ubiquitous expression in placenta adult (RPKM 11.5), CNS E11.5 (RPKM 4.5) and 24 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Swt1 in Genome Data Viewer
    Location:
    1 G1; 1 64.08 cM
    Exon count:
    20
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 1 NC_000067.7 (151243449..151304248, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 1 NC_000067.6 (151367698..151428497, complement)

    Chromosome 1 - NC_000067.7Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer ABC_E4356 Neighboring gene STARR-seq mESC enhancer starr_02612 Neighboring gene predicted gene, 46162 Neighboring gene CapStarr-seq enhancer MGSCv37_chr1:153134717-153134870 Neighboring gene STARR-seq mESC enhancer starr_02614 Neighboring gene STARR-seq mESC enhancer starr_02615 Neighboring gene predicted gene 10138 Neighboring gene STARR-positive B cell enhancer ABC_E3312 Neighboring gene STARR-positive B cell enhancer mm9_chr1:153191350-153191651 Neighboring gene STARR-positive B cell enhancer ABC_E3313 Neighboring gene influenza virus NS1A binding protein Neighboring gene STARR-positive B cell enhancer ABC_E994 Neighboring gene STARR-positive B cell enhancer ABC_E5817 Neighboring gene STARR-seq mESC enhancer starr_02618 Neighboring gene tRNA methyltransferase 1 like Neighboring gene STARR-seq mESC enhancer starr_02619 Neighboring gene microRNA 7682 Neighboring gene ring finger protein 2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Identification of transcripts with enriched expression in the developing and adult pancreas. Hoffman BG, et al. Genome Biol, 2008. PMID 18554416, Free PMC Article
    2. Database resources of the National Center for Biotechnology Information. Wheeler DL, et al. Nucleic Acids Res, 2001 Jan 1. PMID 11125038, Free PMC Article
    3. BayGenomics: a resource of insertional mutations in mouse embryonic stem cells. Stryke D, et al. Nucleic Acids Res, 2003 Jan 1. PMID 12520002, Free PMC Article
    4. Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Hansen GM, et al. Genome Res, 2008 Oct. PMID 18799693, Free PMC Article
    5. Genetic determinants of micronucleus formation in vivo. Adams DJ, et al. Nature, 2024 Mar. PMID 38355793, Free PMC Article

    See all (17) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    transcriptional protein SWT1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_025819.4 → NP_080095.3  transcriptional protein SWT1

      See identical proteins and their annotated locations for NP_080095.3

      Status: VALIDATED

      Source sequence(s)
      AC165946, AK004803, BY062718, CV563132
      Consensus CDS
      CCDS15360.1
      UniProtKB/Swiss-Prot
      E9QP79, Q6PAN2, Q7TMQ6, Q9DBQ9
      Related
      ENSMUSP00000067516.6, ENSMUST00000064771.12
      Conserved Domains (1) summary
      cd09880
      Location:396 → 540
      PIN_Smg5-Smg6-like; PIN domain

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000067.7 Reference GRCm39 C57BL/6J

      Range
      151243449..151304248 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_011248058.2 → XP_011246360.1  transcriptional protein SWT1 isoform X1

      Conserved Domains (1) summary
      cd18727
      Location:150 → 289
      PIN_Swt1-like; VapC-like PIN domain of Saccharomyces cerevisiae Swt1p, human SWT1 and related proteins

    2. XM_030242199.2 → XP_030098059.1  transcriptional protein SWT1 isoform X2

      Conserved Domains (1) summary
      cd18727
      Location:2 → 139
      PIN_Swt1-like; VapC-like PIN domain of Saccharomyces cerevisiae Swt1p, human SWT1 and related proteins

    3. XM_011248059.3 → XP_011246361.1  transcriptional protein SWT1 isoform X2

      Conserved Domains (1) summary
      cd18727
      Location:2 → 139
      PIN_Swt1-like; VapC-like PIN domain of Saccharomyces cerevisiae Swt1p, human SWT1 and related proteins

    RNA

    1. XR_004934079.1 RNA Sequence

    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9DBQ9.3 GenPept UniProtKB/Swiss-Prot:Q9DBQ9

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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