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    RNU1-3 RNA, U1 small nuclear 3 [ Homo sapiens (human) ]

    Gene ID: 26869, updated on 10-Dec-2024

    Summary

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    Official Symbol
    RNU1-3provided by HGNC
    Official Full Name
    RNA, U1 small nuclear 3provided by HGNC
    Primary source
    HGNC:HGNC:10130
    See related
    Ensembl:ENSG00000207513 AllianceGenome:HGNC:10130
    Gene type
    snRNA
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    HSD4; RNU1G3
    Summary
    Predicted to enable pre-mRNA 5'-splice site binding activity. Predicted to be involved in mRNA 5'-splice site recognition. Predicted to be part of U1 snRNP. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See RNU1-3 in Genome Data Viewer
    Location:
    1p36.13
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 1 NC_000001.11 (16666785..16666948, complement)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 1 NC_060925.1 (16382374..16382537, complement)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (16993280..16993443, complement)

    Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:16945048-16945716 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:16945717-16946384 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:16946385-16947053 Neighboring gene CROCC pseudogene 2 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:16950326-16950836 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 334 Neighboring gene CROCC pseudogene 2 Neighboring gene H3K27ac hESC enhancer GRCh37_chr1:16963058-16963558 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:16964533-16965424 Neighboring gene OCT4-H3K4me1 hESC enhancer GRCh37_chr1:16970879-16971669 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:16971670-16972459 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:16973171-16973790 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:16974411-16975030 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:16975031-16975648 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:16976311-16976811 Neighboring gene macrophage stimulating 1 pseudogene 2 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:16983417-16984225 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:16992232-16993198 Neighboring gene FAM231A/C-like protein LOC102723383 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 270 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 335 Neighboring gene tRNA-Gly (CCC) 4-1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Human U1 small nuclear RNA genes: extensive conservation of flanking sequences suggests cycles of gene amplification and transposition. Bernstein LB, et al. Mol Cell Biol, 1985 Sep. PMID 3837185, Free PMC Article
    2. Human U1 loci: genes for human U1 RNA have dramatically similar genomic environments. Manser T, et al. Cell, 1982 May. PMID 6179629
    3. RNA-binding activity of TRIM25 is mediated by its PRY/SPRY domain and is required for ubiquitination. Choudhury NR, et al. BMC Biol, 2017 Nov 8. PMID 29117863, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Phenotypes

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    Review eQTL and phenotype association data in this region using PheGenI

    Variation

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    See variants in ClinVar

    See studies and variants in dbVar

    See Variation Viewer (GRCh37.p13)

    See Variation Viewer (GRCh38)

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Other Names

    • RNA, U1G3 small nuclear

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    RNA

    1. NR_004408.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AL137798
      Related
      ENST00000384782.1

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000001.11 Reference GRCh38.p14 Primary Assembly

      Range
      16666785..16666948 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Reference GRCh38.p14 PATCHES

    Genomic

    1. NW_025791756.1 Reference GRCh38.p14 PATCHES

      Range
      869713..869876
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060925.1 Alternate T2T-CHM13v2.0

      Range
      16382374..16382537 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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