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    CG14100 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 40132, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG14100provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0036889
    Locus tag
    Dmel_CG14100
    See related
    AllianceGenome:FB:FBgn0036889
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG14100
    Summary
    Predicted to enable rRNA (guanosine-2'-O-)-methyltransferase activity. Predicted to be involved in RNA processing. Orthologous to human MRM3 (mitochondrial rRNA methyltransferase 3). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG14100 in Genome Data Viewer
    Location:
    76B8-76B8; 3-45 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (19589072..19590524, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (19582172..19583624, complement)

    Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene Shaker cognate l Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene absent, small, or homeotic discs 1 Neighboring gene TBP-associated factor 6

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genome-wide analysis of Staufen-associated mRNAs identifies secondary structures that confer target specificity. Laver JD, et al. Nucleic Acids Res, 2013 Nov. PMID 23945942, Free PMC Article
    2. Functional screening of mammalian mechanosensitive genes using Drosophila RNAi library- Smarcd3/Bap60 is a mechanosensitive pro-inflammatory gene. Kumar S, et al. Sci Rep, 2016 Nov 7. PMID 27819340, Free PMC Article
    3. Molecular genetic analysis of Chd3 and polytene chromosome region 76B-D in Drosophila melanogaster. Cooper MT, et al. Genetics, 2010 Jul. PMID 20439780, Free PMC Article
    4. A microtubule interactome: complexes with roles in cell cycle and mitosis. Hughes JR, et al. PLoS Biol, 2008 Apr 22. PMID 18433294, Free PMC Article
    5. Hedgehog Signaling Strength Is Orchestrated by the mir-310 Cluster of MicroRNAs in Response to Diet. Çiçek IÖ, et al. Genetics, 2016 Mar. PMID 26801178, Free PMC Article

    See all (27) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables RNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables RNA methyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables rRNA (guanosine-2'-O-)-methyltransferase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Process Evidence Code Pubs
    involved_in RNA processing IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in rRNA processing ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Component Evidence Code Pubs
    is_active_in mitochondrial matrix ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG14100-PA
    NP_649130.2

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.4 Reference assembly

      Range
      19589072..19590524 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_140873.4 → NP_649130.2  uncharacterized protein Dmel_CG14100 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_649130.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q8SZ70, Q9VW14
      UniProtKB/TrEMBL
      H0RNK5
      Related
      FBpp0074739
      Conserved Domains (3) summary
      COG0566
      Location:131 → 399
      SpoU; tRNA G18 (ribose-2'-O)-methylase SpoU [Translation, ribosomal structure and biogenesis]
      pfam00588
      Location:235 → 393
      SpoU_methylase; SpoU rRNA Methylase family
      pfam08032
      Location:141 → 214
      SpoU_sub_bind; RNA 2'-O ribose methyltransferase substrate binding
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VW14.1 Q9VW14

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