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    CG2202 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 32014, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG2202provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0030240
    Locus tag
    Dmel_CG2202
    See related
    AllianceGenome:FB:FBgn0030240
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG2202
    Summary
    Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of DNA-templated transcription. Predicted to be located in nucleus. Is expressed in organism. Orthologous to human ZNF646 (zinc finger protein 646). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG2202 in Genome Data Viewer
    Location:
    9F5-9F5; 1-33 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (10848757..10852327)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (10742790..10746360)

    Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene small bristles Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene 6-phosphogluconolactonase Neighboring gene fascetto Neighboring gene sister of feo

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Feo, the Drosophila homolog of PRC1, is required for central-spindle formation and cytokinesis. Vernì F, et al. Curr Biol, 2004 Sep 7. PMID 15341744
    2. ZAD-Domain Is Essential for Nuclear Localization of Insulator Proteins in Drosophila melanogaster. Zolotarev NA, et al. Acta Naturae, 2016 Jul-Sep. PMID 27795848, Free PMC Article
    3. Innovation of heterochromatin functions drives rapid evolution of essential ZAD-ZNF genes in Drosophila. Kasinathan B, et al. Elife, 2020 Nov 10. PMID 33169670, Free PMC Article
    4. A large-scale resource for tissue-specific CRISPR mutagenesis in Drosophila. Port F, et al. Elife, 2020 Feb 13. PMID 32053108, Free PMC Article
    5. Drosophila miR-277 controls branched-chain amino acid catabolism and affects lifespan. Esslinger SM, et al. RNA Biol, 2013 Jun. PMID 23669073, Free PMC Article

    See all (30) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables transcription cis-regulatory region binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in regulation of DNA-templated transcription IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in regulation of DNA-templated transcription ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nucleus ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG2202-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_004354.4 Reference assembly

      Range
      10848757..10852327
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_132429.4 → NP_572657.2  uncharacterized protein Dmel_CG2202 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_572657.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VZ63
      Related
      FBpp0073236
      Conserved Domains (6) summary
      COG5048
      Location:443 → 730
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:656 → 676
      ZF_C2H2; C2H2 Zn finger [structural motif]
      sd00019
      Location:192 → 213
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:684 → 704
      zf-C2H2; Zinc finger, C2H2 type
      pfam07776
      Location:45 → 121
      zf-AD; Zinc-finger associated domain (zf-AD)
      pfam13465
      Location:696 → 721
      zf-H2C2_2; Zinc-finger double domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q95RW9 Q95RW9
    Q9VZ63 Q9VZ63

    Gene LinkOut

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