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    Ct45a cancer/testis antigen 45 [ Mus musculus (house mouse) ]

    Gene ID: 270599, updated on 13-Jan-2025

    Summary

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    Official Symbol
    Ct45aprovided by MGI
    Official Full Name
    cancer/testis antigen 45provided by MGI
    Primary source
    MGI:MGI:2685494
    See related
    Ensembl:ENSMUSG00000064016 AllianceGenome:MGI:2685494
    Gene type
    protein coding
    RefSeq status
    PREDICTED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Gm648
    Summary
    Predicted to enable identical protein binding activity. Orthologous to several human genes including CT45A1 (cancer/testis antigen family 45 member A1); CT45A10 (cancer/testis antigen family 45 member A10); and CT45A2 (cancer/testis antigen family 45 member A2). [provided by Alliance of Genome Resources, Jan 2025]
    Expression
    Restricted expression toward placenta adult (RPKM 16.5) See more
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    Genomic context

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    See Ct45a in Genome Data Viewer
    Location:
    X A5; X 30.06 cM
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) X NC_000086.8 (55589233..55614583, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) X NC_000086.7 (56543873..56569162, complement)

    Chromosome X - NC_000086.8Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer ABC_E8761 Neighboring gene 40S ribosomal protein S23 pseudogene Neighboring gene integrator complex subunit 6 like Neighboring gene CapStarr-seq enhancer MGSCv37_chrX:53851179-53851288 Neighboring gene microRNA 5116 Neighboring gene membrane magnesium transporter 1 Neighboring gene predicted gene, 36239

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. USP7 represses lineage differentiation genes in mouse embryonic stem cells by both catalytic and noncatalytic activities. Liu C, et al. Sci Adv, 2023 May 19. PMID 37196079, Free PMC Article
    2. Mouse screen reveals multiple new genes underlying mouse and human hearing loss. Ingham NJ, et al. PLoS Biol, 2019 Apr. PMID 30973865, Free PMC Article
    3. Genetic determinants of micronucleus formation in vivo. Adams DJ, et al. Nature, 2024 Mar. PMID 38355793, Free PMC Article
    4. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article
    5. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073

    See all (12) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 
    • Targeted (2) 

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables identical protein binding ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein LOC270599

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001033372.2 → NP_001028544.1  uncharacterized protein LOC270599

      Status: PREDICTED

      Source sequence(s)
      AK146653
      Consensus CDS
      CCDS53075.1
      UniProtKB/TrEMBL
      Q3UJ22
      Related
      ENSMUSP00000079908.5, ENSMUST00000081133.5
      Conserved Domains (1) summary
      pfam15300
      Location:139 → 198
      INT_SG_DDX_CT_C; INTS6/SAGE1/DDX26B/CT45 C-terminus

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000086.8 Reference GRCm39 C57BL/6J

      Range
      55589233..55614583 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_011247598.2 → XP_011245900.2  uncharacterized protein LOC270599 isoform X1

      Conserved Domains (1) summary
      pfam15300
      Location:169 → 230
      INT_SG_DDX_CT_C; INTS6/SAGE1/DDX26B/CT45 C-terminus

    2. XM_006528047.4 → XP_006528110.1  uncharacterized protein LOC270599 isoform X2

      UniProtKB/TrEMBL
      Q3UJ22
      Conserved Domains (1) summary
      pfam15300
      Location:139 → 198
      INT_SG_DDX_CT_C; INTS6/SAGE1/DDX26B/CT45 C-terminus

    3. XM_006528046.1 → XP_006528109.1  uncharacterized protein LOC270599 isoform X2

      UniProtKB/TrEMBL
      Q3UJ22
      Conserved Domains (1) summary
      pfam15300
      Location:139 → 198
      INT_SG_DDX_CT_C; INTS6/SAGE1/DDX26B/CT45 C-terminus

    4. XM_011247599.3 → XP_011245901.1  uncharacterized protein LOC270599 isoform X2

      UniProtKB/TrEMBL
      Q3UJ22
      Conserved Domains (1) summary
      pfam15300
      Location:139 → 198
      INT_SG_DDX_CT_C; INTS6/SAGE1/DDX26B/CT45 C-terminus
    Nucleotide Protein Strain
    Heading Accession and Version

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