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    NRG3 neuregulin 3 [ Homo sapiens (human) ]

    Gene ID: 10718, updated on 4-Jan-2025

    Summary

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    Official Symbol
    NRG3provided by HGNC
    Official Full Name
    neuregulin 3provided by HGNC
    Primary source
    HGNC:HGNC:7999
    See related
    Ensembl:ENSG00000185737 MIM:605533; AllianceGenome:HGNC:7999
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    HRG3; pro-NRG3
    Summary
    This gene is a member of the neuregulin gene family. This gene family encodes ligands for the transmembrane tyrosine kinase receptors ERBB3 and ERBB4 - members of the epidermal growth factor receptor family. Ligand binding activates intracellular signaling cascades and the induction of cellular responses including proliferation, migration, differentiation, and survival or apoptosis. This gene encodes neuregulin 3 (NRG3). NRG3 has been shown to activate the tyrosine phosphorylation of its cognate receptor, ERBB4, and is thought to influence neuroblast proliferation, migration and differentiation by signalling through ERBB4. NRG3 also promotes mammary differentiation during embryogenesis. Linkage studies have implicated this gene as a susceptibility locus for schizophrenia and schizoaffective disorder. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants have been described but their biological validity has not been verified.[provided by RefSeq, Sep 2009]
    Expression
    Biased expression in brain (RPKM 3.4), gall bladder (RPKM 0.5) and 1 other tissue See more
    Orthologs
    mouse all
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    Genomic context

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    See NRG3 in Genome Data Viewer
    Location:
    10q23.1
    Exon count:
    21
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 10 NC_000010.11 (81875194..82987179)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 10 NC_060934.1 (82749017..83860555)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 10 NC_000010.10 (83634950..84746935)

    Chromosome 10 - NC_000010.11Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105378390 Neighboring gene uncharacterized LOC124902549 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:83635899-83636661 Neighboring gene NANOG hESC enhancer GRCh37_chr10:83641632-83642192 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr10:83703221-83703801 Neighboring gene MPRA-validated peak1034 silencer Neighboring gene uncharacterized LOC124902472 Neighboring gene CDK7 strongly-dependent group 2 enhancer GRCh37_chr10:84047967-84049166 Neighboring gene NRG3 antisense RNA 1 Neighboring gene RNA, U6 small nuclear 441, pseudogene Neighboring gene NANOG hESC enhancer GRCh37_chr10:84156597-84157098 Neighboring gene NANOG hESC enhancer GRCh37_chr10:84435047-84435611 Neighboring gene Sharpr-MPRA regulatory region 14045 Neighboring gene ReSE screen-validated silencer GRCh37_chr10:84502591-84502759 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr10:84518678-84519389 Neighboring gene ReSE screen-validated silencer GRCh37_chr10:84570168-84570356 Neighboring gene BRD4-independent group 4 enhancer GRCh37_chr10:84715398-84716597 Neighboring gene NANOG hESC enhancer GRCh37_chr10:84720206-84720727 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr10:84721457-84722098 Neighboring gene NANOG-H3K27ac hESC enhancer GRCh37_chr10:84838063-84838624 Neighboring gene RNA, U6 small nuclear 478, pseudogene Neighboring gene uncharacterized LOC107984187

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Tissue-specific circular RNA induction during human fetal development
    • Description: 35 human fetal samples from 6 tissues (3 - 7 replicates per tissue) collected between 10 and 20 weeks gestational time were sequenced using Illumina TruSeq Stranded Total RNA
    • BioProject: PRJNA270632
    • Publication: PMID 26076956
    • Analysis date: Mon Apr 2 22:54:59 2018

    Bibliography

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    Related articles in PubMed

    1. Temporal, Diagnostic, and Tissue-Specific Regulation of NRG3 Isoform Expression in Human Brain Development and Affective Disorders. Paterson C, et al. Am J Psychiatry, 2017 Mar 1. PMID 27771971, Free PMC Article
    2. Exome sequencing identified NRG3 as a novel susceptible gene of Hirschsprung's disease in a Chinese population. Yang J, et al. Mol Neurobiol, 2013 Jun. PMID 23315268
    3. No genetic evidence for Neuregulin 3 conferring risk of schizophrenia in the Chinese population. Zhang R, et al. Psychiatry Res, 2013 Feb 28. PMID 22981155
    4. Characterization of a neural-specific splicing form of the human neuregulin 3 gene involved in oligodendrocyte survival. Carteron C, et al. J Cell Sci, 2006 Mar 1. PMID 16478787
    5. Neuregulin 3 is associated with attention deficits in schizophrenia and bipolar disorder. Meier S, et al. Int J Neuropsychopharmacol, 2013 Apr. PMID 22831755

    See all (52) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Transcytosis and trans-synaptic retention by postsynaptic ErbB4 underlie axonal accumulation of NRG3.
      Title: Transcytosis and trans-synaptic retention by postsynaptic ErbB4 underlie axonal accumulation of NRG3.
    2. Association of NRG3 and ERBB4 gene polymorphism with nicotine dependence in Turkish population.
      Title: Association of NRG3 and ERBB4 gene polymorphism with nicotine dependence in Turkish population.
    3. Neuregulin 3 rs10748842 polymorphism contributes to the effect of body mass index on cognitive impairment in patients with schizophrenia.
      Title: Neuregulin 3 rs10748842 polymorphism contributes to the effect of body mass index on cognitive impairment in patients with schizophrenia.
    4. NRG3 contributes to cognitive deficits in chronic patients with schizophrenia.
      Title: NRG3 contributes to cognitive deficits in chronic patients with schizophrenia.
    5. The BRE rs7572644 and NRG3 rs1649942 genetic variants were validated in an independent cohort of EOC Portuguese patients.
      Title: Pharmacogenomics in epithelial ovarian cancer first-line treatment outcome: validation of GWAS-associated NRG3 rs1649942 and BRE rs7572644 variants in an independent cohort.
    6. No genetic correlation was found between Hirschsprung disease and the three SNPs at NRG3 (rs10748842, rs10883866 and rs6584400)
      Title: Effects of RET, NRG1 and NRG3 Polymorphisms in a Chinese Population with Hirschsprung Disease.
    7. Data show that Williams-Beuren syndrome transcription factor (WSTF) release was mediated by neuregulin-3 (NRG3) following KRASG12V expression in intestinal epithelial cells.
      Title: KRASG12 mutant induces the release of the WSTF/NRG3 complex, and contributes to an oncogenic paracrine signaling pathway.
    8. These observations encourage investigation of the neurobiology of NRG3 isoforms and highlight inhibition of NRG3 signaling as a potential target for psychiatric treatment development.
      Title: Temporal, Diagnostic, and Tissue-Specific Regulation of NRG3 Isoform Expression in Human Brain Development and Affective Disorders.
    9. common variants of GABRG2, RELN and NRG3 and the GABRG2-RELN-PTCH1 interaction networks might confer altered susceptibility to Hirschsprung disease.
      Title: Contribution of Common Variants in GABRG2, RELN and NRG3 and Interaction Networks to the Risk of Hirschsprung Disease.
    10. these data suggest that Nrg3/ErbB4 signaling may be an important factor in nicotine dependence.
      Title: Evidence from mouse and man for a role of neuregulin 3 in nicotine dependence.
    Submit: New GeneRIF Correction See all GeneRIFs (31)

    Phenotypes

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    Find tests for this gene in the NIH Genetic Testing Registry (GTR)

    Review eQTL and phenotype association data in this region using PheGenI

    Copy number response

    Description
    Copy number response
    Haploinsufficency

    No evidence available (Last evaluated 2011-12-21)

    ClinGen Genome Curation Page
    Triplosensitivity

    No evidence available (Last evaluated 2011-12-21)

    ClinGen Genome Curation PagePubMed

    EBI GWAS Catalog

    Description
    Genome-wide association study of retinopathy in individuals without diabetes.
    EBI GWAS Catalog
    Genome-wide contribution of genotype by environment interaction to variation of diabetes-related traits.
    EBI GWAS Catalog
    Hypertrophy-associated polymorphisms ascertained in a founder cohort applied to heart failure risk and mortality.
    EBI GWAS Catalog
    Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.
    EBI GWAS Catalog
    Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population.
    EBI GWAS Catalog
    Whole genome association study identifies polymorphisms associated with QT prolongation during iloperidone treatment of schizophrenia.
    EBI GWAS Catalog

    Variation

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    See variants in ClinVar

    See studies and variants in dbVar

    See Variation Viewer (GRCh37.p13)

    See Variation Viewer (GRCh38)

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    enables chemorepellent activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables growth factor activity NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    enables receptor ligand activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables receptor tyrosine kinase binding NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    enables transmembrane receptor protein tyrosine kinase activator activity NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in ERBB4 signaling pathway IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in ERBB4 signaling pathway IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in ERBB4-ERBB4 signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in animal organ development IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in chemorepulsion involved in interneuron migration from the subpallium to the cortex IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in intracellular signal transduction IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in mammary placode formation IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in modulation of chemical synaptic transmission IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in modulation of chemical synaptic transmission IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in negative regulation of neuron migration IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in pattern specification process IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in regulation of cell growth NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    involved_in synapse assembly IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in extracellular region NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    is_active_in extracellular space IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in extracellular space IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in glutamatergic synapse IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in glutamatergic synapse IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    located_in plasma membrane NAS
    Non-traceable Author Statement
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    pro-neuregulin-3, membrane-bound isoform
    Names
    neuregulin-3-like polypeptide

    NCBI Reference Sequences (RefSeq)

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    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    Genomic

    1. NG_013373.1 RefSeqGene

      Range
      4881..1116865
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001010848.4 → NP_001010848.2  pro-neuregulin-3, membrane-bound isoform isoform 1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (1) encodes isoform 1.
      Source sequence(s)
      AL096706, AL589782, BC136811, DQ001411
      Consensus CDS
      CCDS31233.1
      UniProtKB/TrEMBL
      B4DKH1
      Related
      ENSP00000361214.2, ENST00000372141.7
      Conserved Domains (2) summary
      PHA02887
      Location:278 → 331
      PHA02887; EGF-like protein; Provisional
      pfam02158
      Location:353 → 486
      Neuregulin; Neuregulin family

    2. NM_001165972.1 → NP_001159444.1  pro-neuregulin-3, membrane-bound isoform isoform 2

      Status: REVIEWED

      Description
      Transcript Variant: This variant (2) uses an alternate in-frame splice site in the 3' coding region, compared to variant 1, resulting in a protein (isoform 2) that is one amino acid shorter, compared to isoform 1.
      Source sequence(s)
      AA704915, AK122886, AL589782, BC136811, DB326565
      UniProtKB/TrEMBL
      B4DKH1, B9EGV5
      Conserved Domains (1) summary
      PHA02887
      Location:278 → 331
      PHA02887; EGF-like protein; Provisional

    3. NM_001165973.2 → NP_001159445.1  pro-neuregulin-3, membrane-bound isoform isoform 3

      Status: REVIEWED

      Description
      Transcript Variant: This variant (3) has multiple differences in the presence and absence of exons in the 5' and 3' ends, compared to variant 1. These differences produce a unique 5' UTR and cause translation initiation at a unique start codon, compared to variant 1. The encoded protein (isoform 3; also known as hFBNRG3) has a shorter and distinct N-terminus and 24 additional aa in its C-terminus, compared to isoform 1. Isoform 3 is exclusively expressed in fetal brain and may undergo N-terminal proteolytic processing following its insertion into the plasma membrane.
      Source sequence(s)
      AA704915, AK122886, AL589782, DB326565, DQ001411, DQ857894
      Consensus CDS
      CCDS53547.1
      UniProtKB/TrEMBL
      D9ZHQ5
      Related
      ENSP00000361215.2, ENST00000372142.6
      Conserved Domains (2) summary
      PHA02887
      Location:38 → 110
      PHA02887; EGF-like protein; Provisional
      pfam02158
      Location:132 → 265
      Neuregulin; Neuregulin family

    4. NM_001370081.1 → NP_001357010.1  pro-neuregulin-3, membrane-bound isoform isoform 4

      Status: REVIEWED

      Source sequence(s)
      AL096706, AL136085, AL354749, AL391478, AL513204, AL589782
      UniProtKB/TrEMBL
      B4DKH1
      Conserved Domains (2) summary
      PHA02887
      Location:278 → 331
      PHA02887; EGF-like protein; Provisional
      pfam02158
      Location:352 → 486
      Neuregulin; Neuregulin family

    5. NM_001370082.1 → NP_001357011.1  pro-neuregulin-3, membrane-bound isoform isoform 5

      Status: REVIEWED

      Source sequence(s)
      AC010157, AL096706, AL136085, AL354749, AL391478, AL513204, AL589782
      UniProtKB/TrEMBL
      D9ZHQ7
      Related
      ENSP00000451376.1, ENST00000556918.5
      Conserved Domains (2) summary
      PHA02887
      Location:82 → 142
      PHA02887; EGF-like protein; Provisional
      pfam02158
      Location:164 → 297
      Neuregulin; Neuregulin family

    6. NM_001370083.1 → NP_001357012.1  pro-neuregulin-3, membrane-bound isoform isoform 6

      Status: REVIEWED

      Source sequence(s)
      AL096706, AL391478

    7. NM_001370084.1 → NP_001357013.1  pro-neuregulin-3, membrane-bound isoform isoform 7

      Status: REVIEWED

      Description
      Transcript Variant: This variant (7) encodes the longest isoform (7).
      Source sequence(s)
      AL096706, AL136085, AL354749, AL391478, AL513204, AL589782
      Consensus CDS
      CCDS91287.1
      UniProtKB/Swiss-Prot
      A4D7U1, P56975, Q0PEH2, Q5VYH3
      UniProtKB/TrEMBL
      B4DKH1, D9ZHP6
      Related
      ENSP00000384796.1, ENST00000404547.5
      Conserved Domains (2) summary
      PHA02887
      Location:278 → 331
      PHA02887; EGF-like protein; Provisional
      pfam02158
      Location:353 → 486
      Neuregulin; Neuregulin family

    RNA

    1. NR_163251.1 RNA Sequence

      Status: REVIEWED

      Source sequence(s)
      AC010157, AL096706, AL136085, AL354749, AL391478, AL513204, AL589782

    2. NR_163252.1 RNA Sequence

      Status: REVIEWED

      Source sequence(s)
      AL096706, AL136085, AL354749, AL391478, AL513204, AL589782

    3. NR_163253.1 RNA Sequence

      Status: REVIEWED

      Source sequence(s)
      AL096706, AL096863, AL136085, AL354749, AL391478, AL513204, AL589782
      Related
      ENST00000602794.5

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000010.11 Reference GRCh38.p14 Primary Assembly

      Range
      81875194..82987179
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017015573.3 → XP_016871062.1  pro-neuregulin-3, membrane-bound isoform isoform X1

      UniProtKB/TrEMBL
      B4DKH1

    2. XM_017015577.3 → XP_016871066.1  pro-neuregulin-3, membrane-bound isoform isoform X5

      UniProtKB/TrEMBL
      B4DKH1

    3. XM_017015574.3 → XP_016871063.1  pro-neuregulin-3, membrane-bound isoform isoform X2

      UniProtKB/TrEMBL
      B4DKH1

    4. XM_017015578.3 → XP_016871067.1  pro-neuregulin-3, membrane-bound isoform isoform X6

      UniProtKB/TrEMBL
      B4DKH1

    5. XM_017015575.3 → XP_016871064.1  pro-neuregulin-3, membrane-bound isoform isoform X3

      UniProtKB/TrEMBL
      B4DKH1

    6. XM_017015579.3 → XP_016871068.1  pro-neuregulin-3, membrane-bound isoform isoform X7

      UniProtKB/TrEMBL
      B4DKH1

    7. XM_017015576.3 → XP_016871065.1  pro-neuregulin-3, membrane-bound isoform isoform X4

      UniProtKB/TrEMBL
      B4DKH1

    8. XM_017015580.3 → XP_016871069.1  pro-neuregulin-3, membrane-bound isoform isoform X8

      UniProtKB/TrEMBL
      B4DKH1

    9. XM_011539172.4 → XP_011537474.1  pro-neuregulin-3, membrane-bound isoform isoform X9

      UniProtKB/TrEMBL
      B4DKH1
      Conserved Domains (2) summary
      PHA02887
      Location:278 → 331
      PHA02887; EGF-like protein; Provisional
      pfam02158
      Location:353 → 487
      Neuregulin; Neuregulin family

    10. XM_011539175.4 → XP_011537477.1  pro-neuregulin-3, membrane-bound isoform isoform X12

      UniProtKB/TrEMBL
      B4DKH1
      Conserved Domains (2) summary
      PHA02887
      Location:278 → 331
      PHA02887; EGF-like protein; Provisional
      pfam02158
      Location:353 → 487
      Neuregulin; Neuregulin family

    11. XM_011539173.4 → XP_011537475.1  pro-neuregulin-3, membrane-bound isoform isoform X10

      UniProtKB/TrEMBL
      B4DKH1
      Conserved Domains (1) summary
      PHA02887
      Location:278 → 331
      PHA02887; EGF-like protein; Provisional

    12. XM_047424512.1 → XP_047280468.1  pro-neuregulin-3, membrane-bound isoform isoform X11

      UniProtKB/TrEMBL
      B4DKH1

    13. XM_017015584.3 → XP_016871073.1  pro-neuregulin-3, membrane-bound isoform isoform X14

    14. XM_017015582.2 → XP_016871071.1  pro-neuregulin-3, membrane-bound isoform isoform X13

      UniProtKB/TrEMBL
      D9ZHP9
      Conserved Domains (2) summary
      PHA02887
      Location:11 → 71
      PHA02887; EGF-like protein; Provisional
      pfam02158
      Location:93 → 227
      Neuregulin; Neuregulin family

    15. XM_024447781.2 → XP_024303549.1  pro-neuregulin-3, membrane-bound isoform isoform X17

      UniProtKB/TrEMBL
      D9ZHQ8
      Related
      ENSP00000441201.1, ENST00000545131.5
      Conserved Domains (1) summary
      pfam02158
      Location:3 → 136
      Neuregulin; Neuregulin family

    16. XM_011539178.3 → XP_011537480.1  pro-neuregulin-3, membrane-bound isoform isoform X15

      UniProtKB/TrEMBL
      D9ZHQ8

    17. XM_047424513.1 → XP_047280469.1  pro-neuregulin-3, membrane-bound isoform isoform X16

      UniProtKB/TrEMBL
      D9ZHQ8

    RNA

    1. XR_001747009.3 RNA Sequence

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060934.1 Alternate T2T-CHM13v2.0

      Range
      82749017..83860555
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_054364607.1 → XP_054220582.1  pro-neuregulin-3, membrane-bound isoform isoform X1

      UniProtKB/TrEMBL
      B4DKH1

    2. XM_054364611.1 → XP_054220586.1  pro-neuregulin-3, membrane-bound isoform isoform X5

      UniProtKB/TrEMBL
      B4DKH1

    3. XM_054364608.1 → XP_054220583.1  pro-neuregulin-3, membrane-bound isoform isoform X2

      UniProtKB/TrEMBL
      B4DKH1

    4. XM_054364612.1 → XP_054220587.1  pro-neuregulin-3, membrane-bound isoform isoform X6

      UniProtKB/TrEMBL
      B4DKH1

    5. XM_054364609.1 → XP_054220584.1  pro-neuregulin-3, membrane-bound isoform isoform X3

      UniProtKB/TrEMBL
      B4DKH1

    6. XM_054364613.1 → XP_054220588.1  pro-neuregulin-3, membrane-bound isoform isoform X7

      UniProtKB/TrEMBL
      B4DKH1

    7. XM_054364610.1 → XP_054220585.1  pro-neuregulin-3, membrane-bound isoform isoform X4

      UniProtKB/TrEMBL
      B4DKH1

    8. XM_054364614.1 → XP_054220589.1  pro-neuregulin-3, membrane-bound isoform isoform X8

      UniProtKB/TrEMBL
      B4DKH1

    9. XM_054364615.1 → XP_054220590.1  pro-neuregulin-3, membrane-bound isoform isoform X9

      UniProtKB/TrEMBL
      B4DKH1

    10. XM_054364618.1 → XP_054220593.1  pro-neuregulin-3, membrane-bound isoform isoform X12

      UniProtKB/TrEMBL
      B4DKH1

    11. XM_054364616.1 → XP_054220591.1  pro-neuregulin-3, membrane-bound isoform isoform X10

      UniProtKB/TrEMBL
      B4DKH1

    12. XM_054364617.1 → XP_054220592.1  pro-neuregulin-3, membrane-bound isoform isoform X11

      UniProtKB/TrEMBL
      B4DKH1

    13. XM_054364620.1 → XP_054220595.1  pro-neuregulin-3, membrane-bound isoform isoform X14

    14. XM_054364619.1 → XP_054220594.1  pro-neuregulin-3, membrane-bound isoform isoform X13

      UniProtKB/TrEMBL
      D9ZHP9

    15. XM_054364623.1 → XP_054220598.1  pro-neuregulin-3, membrane-bound isoform isoform X17

      UniProtKB/TrEMBL
      D9ZHQ8

    16. XM_054364621.1 → XP_054220596.1  pro-neuregulin-3, membrane-bound isoform isoform X15

      UniProtKB/TrEMBL
      D9ZHQ8

    17. XM_054364622.1 → XP_054220597.1  pro-neuregulin-3, membrane-bound isoform isoform X16

      UniProtKB/TrEMBL
      D9ZHQ8

    RNA

    1. XR_008488156.1 RNA Sequence

    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P56975.1 GenPept UniProtKB/Swiss-Prot:P56975

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