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    Rad51ap2 RAD51 associated protein 2 [ Mus musculus (house mouse) ]

    Gene ID: 209550, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Rad51ap2provided by MGI
    Official Full Name
    RAD51 associated protein 2provided by MGI
    Primary source
    MGI:MGI:3644580
    See related
    Ensembl:ENSMUSG00000086022 AllianceGenome:MGI:3644580
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    EG209550
    Summary
    Predicted to be part of protein-containing complex. Orthologous to human RAD51AP2 (RAD51 associated protein 2). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Low expression observed in reference dataset See more
    Orthologs
    human all
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    Genomic context

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    See Rad51ap2 in Genome Data Viewer
    Location:
    12 A1.1; 12 5.58 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 12 NC_000078.7 (11506024..11513154)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 12 NC_000078.6 (11456023..11463153)

    Chromosome 12 - NC_000078.7Genomic Context describing neighboring genes Neighboring gene visinin-like 1 Neighboring gene STARR-seq mESC enhancer starr_31541 Neighboring gene RIKEN cDNA 4930511A02 gene Neighboring gene STARR-seq mESC enhancer starr_31542 Neighboring gene STARR-seq mESC enhancer starr_31543 Neighboring gene heat shock protein 1 (chaperonin) pseudogene 9 Neighboring gene predicted gene 6867

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. RAD51AP2 is required for efficient meiotic recombination between X and Y chromosomes. Ma H, et al. Sci Adv, 2022 Jan 14. PMID 35020426, Free PMC Article
    2. Genetic determinants of micronucleus formation in vivo. Adams DJ, et al. Nature, 2024 Mar. PMID 38355793, Free PMC Article
    3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    part_of protein-containing complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of protein-containing complex ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    RAD51-associated protein 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001111118.2 → NP_001104588.1  RAD51-associated protein 2

      See identical proteins and their annotated locations for NP_001104588.1

      Status: VALIDATED

      Source sequence(s)
      AC139207, CT009765
      Consensus CDS
      CCDS49029.1
      UniProtKB/TrEMBL
      G3UW63
      Related
      ENSMUSP00000128854.2, ENSMUST00000124065.2
      Conserved Domains (1) summary
      pfam15696
      Location:937 → 975
      RAD51_interact; RAD51 interacting motif

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000078.7 Reference GRCm39 C57BL/6J

      Range
      11506024..11513154
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_030246640.1 → XP_030102500.1  RAD51-associated protein 2 isoform X2

      Conserved Domains (2) summary
      pfam16304
      Location:8 → 72
      DUF4946; Domain of unknown function (DUF4946)
      pfam15696
      Location:129 → 167
      RAD51_interact; RAD51 interacting motif

    2. XM_030246639.2 → XP_030102499.1  RAD51-associated protein 2 isoform X1

      Conserved Domains (1) summary
      pfam15696
      Location:143 → 181
      RAD51_interact; RAD51 interacting motif
    Nucleotide Protein Strain
    Heading Accession and Version

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