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    Zkscan16 zinc finger with KRAB and SCAN domains 16 [ Mus musculus (house mouse) ]

    Gene ID: 100041581, updated on 9-Dec-2024

    Summary

    Official Symbol
    Zkscan16provided by MGI
    Official Full Name
    zinc finger with KRAB and SCAN domains 16provided by MGI
    Primary source
    MGI:MGI:3510405
    See related
    Ensembl:ENSMUSG00000038630 AllianceGenome:MGI:3510405
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Zfp483; XM_143800
    Summary
    Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Is expressed in central nervous system and genitourinary system. Orthologous to human ZNF483 (zinc finger protein 483). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in cortex adult (RPKM 7.1), frontal lobe adult (RPKM 6.6) and 7 other tissues See more
    Orthologs
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    Genomic context

    See Zkscan16 in Genome Data Viewer
    Location:
    4 B3; 4 32.36 cM
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (58943568..58962624)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (58943568..58962624)

    Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene olfactory receptor family 2 subfamily K member 2 Neighboring gene Ecm29 proteasome adaptor and scaffold Neighboring gene STARR-positive B cell enhancer ABC_E6181 Neighboring gene prostaglandin reductase 1 Neighboring gene STARR-positive B cell enhancer ABC_E9587 Neighboring gene DnaJ heat shock protein family (Hsp40) member C25

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    General gene information

    Gene Ontology Provided by MGI

    Component Evidence Code Pubs
    is_active_in nucleus  

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001099323.3NP_001092793.1  zinc finger protein 483

      See identical proteins and their annotated locations for NP_001092793.1

      Status: VALIDATED

      Source sequence(s)
      AK032125, AL805972
      Consensus CDS
      CCDS38771.1
      UniProtKB/TrEMBL
      A2ALW2
      Related
      ENSMUSP00000103178.2, ENSMUST00000107554.2
      Conserved Domains (5) summary
      smart00349
      Location:170223
      KRAB; krueppel associated box
      COG5048
      Location:537725
      COG5048; FOG: Zn-finger [General function prediction only]
      PRK07219
      Location:383489
      PRK07219; DNA topoisomerase I; Validated
      sd00017
      Location:513533
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam02023
      Location:45132
      SCAN; SCAN domain
    2. NM_001355408.1NP_001342337.1  zinc finger protein 483

      Status: VALIDATED

      Source sequence(s)
      AK032125, AL805972
      Consensus CDS
      CCDS38771.1
      UniProtKB/TrEMBL
      A2ALW2
      Conserved Domains (5) summary
      smart00349
      Location:170223
      KRAB; krueppel associated box
      COG5048
      Location:537725
      COG5048; FOG: Zn-finger [General function prediction only]
      PRK07219
      Location:383489
      PRK07219; DNA topoisomerase I; Validated
      sd00017
      Location:513533
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam02023
      Location:45132
      SCAN; SCAN domain

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000070.7 Reference GRCm39 C57BL/6J

      Range
      58943568..58962624
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006537508.2XP_006537571.1  zinc finger protein 483 isoform X1

      See identical proteins and their annotated locations for XP_006537571.1

      UniProtKB/TrEMBL
      A2ALW2
      Conserved Domains (5) summary
      smart00349
      Location:170223
      KRAB; krueppel associated box
      COG5048
      Location:537725
      COG5048; FOG: Zn-finger [General function prediction only]
      PRK07219
      Location:383489
      PRK07219; DNA topoisomerase I; Validated
      sd00017
      Location:513533
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam02023
      Location:45132
      SCAN; SCAN domain
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